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microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...
Aliases for MIR5685 Gene
Subcategory (RNA class) for MIR5685 Gene
miRNA
Number of RNA Genes sources:
1 / 17
Aliases for MIR5685 Gene
External Ids for MIR5685 Gene
- HGNC: 43543
- Entrez Gene: 100847075
- Ensembl: ENSG00000264056
Previous GeneCards Identifiers for MIR5685 Gene
- GC06U902255
- GC06P053143
Summaries for MIR5685 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR5685 Gene
MIR5685 (MicroRNA 5685) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR5685 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5685 Gene
Genomics for MIR5685 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MIR5685 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06J053278 | Enhancer | 0.3 | dbSUPER | 600.7 | +1.6 | 1585 | 0.7 | SCRT2 SCRT1 | MIR5685 RF00017-5602 GCM1 lnc-GCM1-4 ELOVL5 MN298114-205 | |
| GH06J053275 | Enhancer | 0.2 | dbSUPER | 600.7 | -0.4 | -424 | 1.2 | MIR5685 ELOVL5 GCM1 lnc-GCM1-4 MN298114-205 | ||
| GH06J053279 | Enhancer | 1 | Ensembl ENCODE dbSUPER | 0.4 | +6.1 | 6108 | 6.2 | TCF12 IKZF2 EED DPF2 RELB RUNX3 IKZF1 NR2F1 GATA3 JUNB | ELOVL5 RPL31P28 RF00017-5602 MIR5685 GCM1 lnc-GCM1-4 MN298114-205 | |
| GH06J053271 | Enhancer | 0.4 | dbSUPER | 0.7 | -4.0 | -4003 | 3.1 | SCRT2 CTCF RAD21 HLF | ELOVL5 MIR5685 GCM1 MN298114-205 | |
| GH06J053263 | Enhancer | 0.5 | Ensembl ENCODE dbSUPER | 0.4 | -12.2 | -12192 | 2.8 | GCM1 ELOVL5 MIR5685 MN298114-205 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MIR5685 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for MIR5685 Gene
Genomic Locations for MIR5685 Gene
- chr6:53,276,993-53,277,071
- (GRCh38/hg38)
- Size:
- 79 bases
- Orientation:
- Plus strand
- chr6:53,141,791-53,141,869
- (GRCh37/hg19)
- Size:
- 79 bases
- Orientation:
- Plus strand
Genomic View for MIR5685 Gene
Genes around MIR5685 on UCSC Golden Path with GeneCards custom track
MIR5685 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
- Cytogenetic band:
-
- 6p12.1 by HGNC
- 6p12.1 by Entrez Gene
- 6p12.1 by Ensembl
MIR5685 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR5685 Gene
Proteins for MIR5685 Gene
Post-translational modifications for MIR5685 Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR5685
- Origene Custom Protein Services for MIR5685
No data available for DME Specific Peptides for MIR5685 Gene
Domains & Families for MIR5685 Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5685 Gene
Function for MIR5685 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MIR5685 - Select products 50% OFF >
- * MIR5685 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for MIR5685
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR5685 - Select products 50% OFF >
- * MIR5685 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5685 Gene
Localization for MIR5685 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5685 Gene
Transcripts for MIR5685 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR5685 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS000075D3B4_9606 | precursor_RNA | 79 | 4 |
HGNC: 43543, RefSeq: NR_049866, Ensembl: ENST00000579080 (view in UCSC) , miRBase: MI0019287, |
| URS000075B307_9606 | miRNA | 22 | 2 |
RefSeq: NR_049866, miRBase: MIMAT0022475, |
MIR5685 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MIR5685 - Select products 50% OFF >
- * MIR5685 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for MIR5685
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR5685 - Select products 50% OFF >
- * MIR5685 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
Relevant External Links for MIR5685 Gene
- GeneLoc Exon Structure for
- MIR5685
No data available for mRNA/cDNA for MIR5685 Gene
Expression for MIR5685 Gene
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5685 Gene
Orthologs for MIR5685 Gene
No data available for Orthologs for MIR5685 Gene
Paralogs for MIR5685 Gene
No data available for Paralogs for MIR5685 Gene
Variants for MIR5685 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2763940 | CNV | gain+loss | 21179565 |
| nsv1033994 | CNV | gain | 25217958 |
Additional Variant Information for MIR5685 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR5685
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5685 Gene
Disorders for MIR5685 Gene
Additional Disease Information for MIR5685
No disorders were found for MIR5685 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5685 Gene
Publications for MIR5685 Gene
- MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
ExternalLinks
Products for MIR5685 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR5685
- Origene Custom Protein Services for MIR5685
- Browse OriGene Inhibitory RNA Products For MIR5685
- OriGene qPCR primer pairs for MIR5685
- Browse CRISPR knockouts for MIR5685
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR5685
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for MIR5685
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for MIR5685
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MIR5685
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for MIR5685
Sources for MIR5685 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB