microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5684 Gene

Subcategory (RNA class) for MIR5684 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR5684 Gene

  • MicroRNA 5684 2 3 5
  • Hsa-Mir-5684 2 3
  • MIR5684 2 5
  • Hsa-MiR-5684 173
  • MIMAT0022473 50
  • MI0019285 50

External Ids for MIR5684 Gene

Previous GeneCards Identifiers for MIR5684 Gene

  • GC19U901585
  • GC19P012898

Summaries for MIR5684 Gene

Entrez Gene Summary for MIR5684 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5684 Gene

MIR5684 (MicroRNA 5684) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5684 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5684 Gene

Genomics for MIR5684 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR5684 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J012774 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 -1.3 -1333 23 BRCA1 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A CTCF ZBTB33 ATF7 TEAD4 ENSG00000267212 MIR5684 HOOK2 IER2 CCDC130 ZNF136 TRMT1 ZNF44 ZNF564 ZNF791
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5684 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR5684 Gene

Genomic Locations for MIR5684 Gene
chr19:12,787,128-12,787,192
(GRCh38/hg38)
Size:
65 bases
Orientation:
Plus strand
chr19:12,897,942-12,898,006
(GRCh37/hg19)
Size:
65 bases
Orientation:
Plus strand

Genomic View for MIR5684 Gene

Genes around MIR5684 on UCSC Golden Path with GeneCards custom track
MIR5684 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR5684 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5684 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5684 Gene

Proteins for MIR5684 Gene

Post-translational modifications for MIR5684 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5684 Gene

Domains & Families for MIR5684 Gene

Gene Families for MIR5684 Gene

HGNC:
genes like me logo Genes that share domains with MIR5684: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5684 Gene

Function for MIR5684 Gene

Phenotypes From GWAS Catalog for MIR5684 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5684 Gene

Localization for MIR5684 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5684 Gene

Pathways & Interactions for MIR5684 Gene

PathCards logo

SuperPathways for MIR5684 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR5684 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR5684 Gene

Drugs & Compounds for MIR5684 Gene

No Compound Related Data Available

Transcripts for MIR5684 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR5684 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B768_9606 precursor_RNA 65 4

HGNC: 43544,

RefSeq: NR_049864,

Ensembl: ENST00000585074 (view in UCSC) ,

miRBase: MI0019285,

URS000075BF22_9606 miRNA 20 3

RefSeq: NR_049864,

miRBase: MIMAT0022473,

TarBase: hsa-miR-5684,

MIR5684 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5684 Gene

No ASD Table

Relevant External Links for MIR5684 Gene

GeneLoc Exon Structure for
MIR5684

No data available for mRNA/cDNA for MIR5684 Gene

Expression for MIR5684 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5684 Gene

Orthologs for MIR5684 Gene

Evolution for MIR5684 Gene

ENSEMBL:
Gene Tree for MIR5684 (if available)
TreeFam:
Gene Tree for MIR5684 (if available)

No data available for Orthologs for MIR5684 Gene

Paralogs for MIR5684 Gene

No data available for Paralogs for MIR5684 Gene

Variants for MIR5684 Gene

Additional dbSNP identifiers (rs#s) for MIR5684 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR5684 Gene

Variant ID Type Subtype PubMed ID
dgv138n111 CNV deletion 26073780
nsv1160586 CNV duplication 26073780
nsv953977 CNV deletion 24416366

Additional Variant Information for MIR5684 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5684

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5684 Gene

Disorders for MIR5684 Gene

No disorders were found for MIR5684 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5684 Gene

Publications for MIR5684 Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR5684 Gene

Sources for MIR5684 Gene