Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR5589 Gene

Subcategory (RNA class) for MIR5589 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5589 Gene

  • MicroRNA 5589 2 3 5
  • Hsa-Mir-5589 3

External Ids for MIR5589 Gene

Previous GeneCards Identifiers for MIR5589 Gene

  • GC19U901601
  • GC19P010154
  • GC19P010155

Summaries for MIR5589 Gene

Entrez Gene Summary for MIR5589 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5589 Gene

MIR5589 (MicroRNA 5589) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5589 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5589 Gene

Genomics for MIR5589 Gene

GeneHancer (GH) Regulatory Elements for MIR5589 Gene

Promoters and enhancers for MIR5589 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I010036 Enhancer 0.7 ENCODE 550.8 -1.5 -1544 0.4 SOX13 FOXA2 MAX CEBPG ZNF644 RAD21 YY1 HNF4G ATF7 THAP11 C3P1 MIR5589 RDH8
GH19I010074 Enhancer 0.7 ENCODE 0.3 +36.1 36066 0.2 CTCF USF1 MAX RAD21 ZNF507 ZNF280A CC2D1A ZNF350 ZNF143 CBFA2T2 ZNF266 KRI1 ILF3 ZNF317 ZNF559 RAVER1 ZNF699 DNMT1 LOC100419831 C19orf66
GH19I010071 Enhancer 0.6 ENCODE 0.3 +32.9 32946 0.2 FOXA2 RXRA MAX RAD21 FOXA1 NR2F2 GABPA YY1 JUND ATF3 PPAN PPAN-P2RY11 ANGPTL6 RDH8 COL5A3 EIF3G OLFM2 C19orf66 MIR5589 C3P1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5589 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5589 Gene

Genomic Locations for MIR5589 Gene
chr19:10,038,354-10,038,413
(GRCh38/hg38)
Size:
60 bases
Orientation:
Plus strand
chr19:10,149,030-10,149,089
(GRCh37/hg19)

Genomic View for MIR5589 Gene

Genes around MIR5589 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5589 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5589 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5589 Gene

Proteins for MIR5589 Gene

Post-translational modifications for MIR5589 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5589 Gene

Domains & Families for MIR5589 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5589 Gene

Function for MIR5589 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5589 Gene

Localization for MIR5589 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5589 Gene

Pathways & Interactions for MIR5589 Gene

SuperPathways for MIR5589 Gene

No Data Available

Interacting Proteins for MIR5589 Gene

Gene Ontology (GO) - Biological Process for MIR5589 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5589 Gene

Drugs & Compounds for MIR5589 Gene

No Compound Related Data Available

Transcripts for MIR5589 Gene

mRNA/cDNA for MIR5589 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5589 Gene

No ASD Table

Relevant External Links for MIR5589 Gene

GeneLoc Exon Structure for
MIR5589
ECgene alternative splicing isoforms for
MIR5589

Expression for MIR5589 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5589 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5589 Gene:

MIR5589
genes like me logo Genes that share expression patterns with MIR5589: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5589 Gene

Orthologs for MIR5589 Gene

Evolution for MIR5589 Gene

ENSEMBL:
Gene Tree for MIR5589 (if available)
TreeFam:
Gene Tree for MIR5589 (if available)

No data available for Orthologs for MIR5589 Gene

Paralogs for MIR5589 Gene

No data available for Paralogs for MIR5589 Gene

Variants for MIR5589 Gene

Sequence variations from dbSNP and Humsavar for MIR5589 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1003401813 -- 10,036,491(+) A/G upstream_transcript_variant
rs1005045881 -- 10,038,051(+) A/G upstream_transcript_variant
rs1005076855 -- 10,037,755(+) G/T upstream_transcript_variant
rs1007599382 -- 10,036,376(+) T/C upstream_transcript_variant
rs1007937138 -- 10,037,635(+) C/G upstream_transcript_variant

Additional Variant Information for MIR5589 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5589

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5589 Gene

Disorders for MIR5589 Gene

Additional Disease Information for MIR5589

No disorders were found for MIR5589 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5589 Gene

Publications for MIR5589 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5589 Gene

Sources for MIR5589 Gene

Content
Loading form....