microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5584 Gene

Subcategory (RNA class) for MIR5584 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR5584 Gene

  • MicroRNA 5584 2 3 5
  • Hsa-Mir-5584 2 3
  • MIR5584 2 5
  • MIMAT0022283 50
  • MIMAT0022284 50
  • MI0019141 50

External Ids for MIR5584 Gene

Previous GeneCards Identifiers for MIR5584 Gene

  • GC01U903365
  • GC01P045021

Summaries for MIR5584 Gene

Entrez Gene Summary for MIR5584 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5584 Gene

MIR5584 (MicroRNA 5584) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5584 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5584 Gene

Genomics for MIR5584 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR5584 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J044545 Enhancer 0.6 Ensembl dbSUPER 600.7 +0.5 507 1.2 ZFHX2 FEZF1 FOS JUND EGR2 MZF1 MIR5584 ERI3 RNU6-369P RNF220 lnc-C1orf228-5 TMEM53
GH01J044546 Enhancer 0.5 dbSUPER 600.7 +1.6 1636 1 CTCF REST FEZF1 RAD21 MZF1 CC2D1A MIR5584 ERI3 RNU6-369P RNF220 DMAP1 lnc-C1orf228-5 TMEM53
GH01J044548 Enhancer 0.3 Ensembl dbSUPER 600.7 -0.4 -392 0.2 MIR5584 RNF220 RNU6-369P ERI3 piR-34822-009 TMEM53
GH01J044541 Enhancer 1 ENCODE CraniofacialAtlas dbSUPER 0.7 -2.3 -2297 2.4 ZIC2 POLR2A ZNF766 EZH2 CEBPG ATF4 SIN3A CEBPB ATF3 CTCF RNF220 RNU6-369P ERI3 ATP6V0B MIR5584 piR-34822-009 TMEM53
GH01J044523 Enhancer 1.7 VISTA UCNEbase ENCODE CraniofacialAtlas dbSUPER 0.4 -21.0 -21023 3.1 TEAD4 ZNF512 RFX1 PRDM1 PKNOX1 POLR2A EZH2 DPF2 TCF12 MCM7 RNF220 ERI3 piR-34822-009 MIR5584 TMEM53
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5584 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR5584 Gene

Genomic Locations for MIR5584 Gene
chr1:44,545,493-44,545,552
(GRCh38/hg38)
Size:
60 bases
Orientation:
Plus strand
chr1:45,011,165-45,011,224
(GRCh37/hg19)
Size:
60 bases
Orientation:
Plus strand

Genomic View for MIR5584 Gene

Genes around MIR5584 on UCSC Golden Path with GeneCards custom track
MIR5584 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR5584 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5584 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5584 Gene

Proteins for MIR5584 Gene

Post-translational modifications for MIR5584 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5584 Gene

Domains & Families for MIR5584 Gene

Gene Families for MIR5584 Gene

HGNC:
genes like me logo Genes that share domains with MIR5584: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5584 Gene

Function for MIR5584 Gene

Phenotypes From GWAS Catalog for MIR5584 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5584 Gene

Localization for MIR5584 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5584 Gene

Pathways & Interactions for MIR5584 Gene

PathCards logo

SuperPathways for MIR5584 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR5584 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR5584 Gene

Drugs & Compounds for MIR5584 Gene

No Compound Related Data Available

Transcripts for MIR5584 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR5584 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E3BF_9606 precursor_RNA 60 4

HGNC: 43507,

RefSeq: NR_049849,

Ensembl: ENST00000581357 (view in UCSC) ,

miRBase: MI0019141,

URS000075A021_9606 miRNA 22 2

RefSeq: NR_049849,

miRBase: MIMAT0022284,

URS000075A332_9606 miRNA 22 2

RefSeq: NR_049849,

miRBase: MIMAT0022283,

MIR5584 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5584 Gene

No ASD Table

Relevant External Links for MIR5584 Gene

GeneLoc Exon Structure for
MIR5584

No data available for mRNA/cDNA for MIR5584 Gene

Expression for MIR5584 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5584 Gene

Orthologs for MIR5584 Gene

Evolution for MIR5584 Gene

ENSEMBL:
Gene Tree for MIR5584 (if available)
TreeFam:
Gene Tree for MIR5584 (if available)

No data available for Orthologs for MIR5584 Gene

Paralogs for MIR5584 Gene

No data available for Paralogs for MIR5584 Gene

Variants for MIR5584 Gene

Additional dbSNP identifiers (rs#s) for MIR5584 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR5584 Gene

Variant ID Type Subtype PubMed ID
nsv461395 CNV gain 19166990
nsv546144 CNV gain 21841781
nsv744 CNV insertion 18451855

Additional Variant Information for MIR5584 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5584

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5584 Gene

Disorders for MIR5584 Gene

Additional Disease Information for MIR5584

No disorders were found for MIR5584 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5584 Gene

Publications for MIR5584 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR5584 Gene

Sources for MIR5584 Gene