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Aliases for MIR5581 Gene

Subcategory (RNA class) for MIR5581 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR5581 Gene

  • MicroRNA 5581 2 3 5
  • Hsa-Mir-5581 3

External Ids for MIR5581 Gene

Previous GeneCards Identifiers for MIR5581 Gene

  • GC01U903354
  • GC01M037969

Summaries for MIR5581 Gene

Entrez Gene Summary for MIR5581 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5581 Gene

MIR5581 (MicroRNA 5581) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5581 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5581 Gene

Genomics for MIR5581 Gene

GeneHancer (GH) Regulatory Elements for MIR5581 Gene

Promoters and enhancers for MIR5581 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J037498 Enhancer 1 Ensembl ENCODE dbSUPER 650.7 +1.6 1625 1.3 REST RFX5 SP1 ZNF121 NFIC JUND ATF3 ZBTB48 ZNF600 FOSL2 MIR5581 GNL2 DNALI1 MEAF6 C1orf109 CDCA8 EPHA10 LINC01137 PIR46555
GH01J037513 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.4 -13.6 -13638 2.6 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B MEAF6 SF3A3 GNL2 FTH1P1 DNALI1 INPP5B SNIP1 RPS27P9 YRDC C1orf109
GH01J037497 Enhancer 0.8 ENCODE dbSUPER 0.7 +3.0 2952 0.1 NFIA ZBTB6 NFIB YY2 ZNF10 ZNF600 ZFX YY1 ZC3H12A LINC01137 DNALI1 RPS27P9 SNIP1 MIR5581 MEAF6 PIR46555
GH01J037496 Enhancer 0.4 UCNEbase 0.7 +4.3 4329 0.3 ZC3H12A LINC01137 RPS27P9 SNIP1 DNALI1 MIR5581 PIR46555 MEAF6
GH01J037507 Enhancer 0.7 ENCODE dbSUPER 0.4 -7.1 -7126 0.9 EED IKZF1 JUNB BATF IKZF2 IRF4 DNALI1 LINC01137 ZC3H12A SNIP1 RPS27P9 GNL2 MEAF6 MIR5581
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5581 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5581 Gene

Genomic Locations for MIR5581 Gene
chr1:37,500,935-37,500,994
(GRCh38/hg38)
Size:
60 bases
Orientation:
Minus strand
chr1:37,966,536-37,966,595
(GRCh37/hg19)
Size:
60 bases
Orientation:
Minus strand

Genomic View for MIR5581 Gene

Genes around MIR5581 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5581 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5581 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5581 Gene

ORGUL Member Location for MIR5581 Gene

ORGUL Member Location for MIR5581 gene

Function for MIR5581 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5581 Gene

Localization for MIR5581 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5581 Gene

Pathways & Interactions for MIR5581 Gene

SuperPathways for MIR5581 Gene

No Data Available

Interacting Proteins for MIR5581 Gene

Gene Ontology (GO) - Biological Process for MIR5581 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5581 Gene

Drugs & Compounds for MIR5581 Gene

No Compound Related Data Available

Transcripts for MIR5581 Gene

mRNA/cDNA for MIR5581 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5581 Gene

No ASD Table

Relevant External Links for MIR5581 Gene

GeneLoc Exon Structure for
MIR5581
ECgene alternative splicing isoforms for
MIR5581

Expression for MIR5581 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5581 Gene:

MIR5581
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5581 Gene

Orthologs for MIR5581 Gene

Evolution for MIR5581 Gene

ENSEMBL:
Gene Tree for MIR5581 (if available)
TreeFam:
Gene Tree for MIR5581 (if available)

No data available for Orthologs for MIR5581 Gene

Paralogs for MIR5581 Gene

No data available for Paralogs for MIR5581 Gene

Variants for MIR5581 Gene

Sequence variations from dbSNP and Humsavar for MIR5581 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000980879 -- 37,501,337(-) G/A upstream_transcript_variant
rs1001118570 -- 37,502,490(-) G/C upstream_transcript_variant
rs1002216716 -- 37,501,605(-) T/C upstream_transcript_variant
rs1005760209 -- 37,502,447(-) G/A upstream_transcript_variant
rs1005993234 -- 37,502,901(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5581 Gene

Variant ID Type Subtype PubMed ID
nsv519551 CNV gain 19592680
nsv524834 CNV gain 19592680

Additional Variant Information for MIR5581 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5581

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5581 Gene

Disorders for MIR5581 Gene

Additional Disease Information for MIR5581

No disorders were found for MIR5581 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5581 Gene

Publications for MIR5581 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5581 Gene

Sources for MIR5581 Gene

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