microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR555 Gene

Data sources for MIR555 Gene:

RNA type for MIR555 Gene

miRNA

Aliases for MIR555 Gene

External Ids for MIR555 Gene

Previous HGNC Symbols for MIR555 Gene

  • MIRN555

Previous GeneCards Identifiers for MIR555 Gene

  • GC01M153584
  • GC01M155316
  • GC01M155347
  • GC01M155336

Summaries for MIR555 Gene

Entrez Gene Summary for MIR555 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR555 Gene

MIR555 (MicroRNA 555) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR555 include Poliomyelitis and Myopathy, Centronuclear, 1. Among its related pathways are Chromatin organization and PKMTs methylate histone lysines.

Additional gene information for MIR555 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR555 Gene

Genomics for MIR555 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR555 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR555 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR555 Gene

Latest Assembly
chr1:155,346,350-155,346,445
(GRCh38/hg38)
Size:
96 bases
Orientation:
Minus strand

Previous Assembly
chr1:155,316,141-155,316,236
(GRCh37/hg19 by Entrez Gene)
Size:
96 bases
Orientation:
Minus strand

Genomic View for MIR555 Gene

Genes around MIR555 on UCSC Golden Path with GeneCards custom track
MIR555 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR555 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR555 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR555 Gene

Proteins for MIR555 Gene

Post-translational modifications for MIR555 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR555 Gene

Domains & Families for MIR555 Gene

Gene Families for MIR555 Gene

HGNC:
genes like me logo Genes that share domains with MIR555: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR555 Gene

Function for MIR555 Gene

Phenotypes From GWAS Catalog for MIR555 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR555 Gene

Localization for MIR555 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR555 Gene

Pathways & Interactions for MIR555 Gene

genes like me logo Genes that share pathways with MIR555: view

Pathways by source for MIR555 Gene

1 BioSystems pathway for MIR555 Gene

Gene Ontology (GO) - Biological Process for MIR555 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR555 Gene

Drugs & Compounds for MIR555 Gene

No Compound Related Data Available

Transcripts for MIR555 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR555 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075E19D_9606 precursor_RNA 96 3

RefSeq: NR_030282,

Ensembl: ENST00000384987 (view in UCSC) ,

miRBase: MI0003561,

URS000075B6A9_9606 miRNA 21 2

RefSeq: NR_030282,

miRBase: MIMAT0003219,

MIR555 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR555 Gene

No ASD Table

Relevant External Links for MIR555 Gene

GeneLoc Exon Structure for
MIR555

No data available for mRNA/cDNA for MIR555 Gene

Expression for MIR555 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR555 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR555

genes like me logo Genes that share expression patterns with MIR555: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR555 Gene

Orthologs for MIR555 Gene

Evolution for MIR555 Gene

ENSEMBL:
Gene Tree for MIR555 (if available)
TreeFam:
Gene Tree for MIR555 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR555

No data available for Orthologs for MIR555 Gene

Paralogs for MIR555 Gene

No data available for Paralogs for MIR555 Gene

Variants for MIR555 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR555 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR555 Gene

Variant ID Type Subtype PubMed ID
esv33869 CNV loss 17666407
nsv831636 CNV loss 17160897

Additional Variant Information for MIR555 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR555
Leiden Open Variation Database (LOVD)
MIR555

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR555 Gene

Disorders for MIR555 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MIR555 Gene - From: COP

Disorder Aliases PubMed IDs
poliomyelitis
  • infantile paralysis
myopathy, centronuclear, 1
  • cnm1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR555

genes like me logo Genes that share disorders with MIR555: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR555 Gene

Publications for MIR555 Gene

  1. MicroRNA-555 has potent antiviral properties against poliovirus. (PMID: 26683768) Shim BS … Tripp RA (The Journal of general virology 2016) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR555 Gene

Sources for MIR555 Gene