microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548V Gene

Data sources for MIR548V Gene:

Subcategory (RNA class) for MIR548V Gene

miRNA

Aliases for MIR548V Gene

External Ids for MIR548V Gene

Previous GeneCards Identifiers for MIR548V Gene

  • GC08U901463
  • GC08M017539

Summaries for MIR548V Gene

Entrez Gene Summary for MIR548V Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548V Gene

MIR548V (MicroRNA 548v) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548V Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548V Gene

Genomics for MIR548V Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR548V Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J017672 Promoter/Enhancer 1.5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +6.6 6636 5.4 FEZF1 ZIC2 ZNF610 ZNF513 ZNF639 KLF7 ZNF341 RXRA SIN3A ZNF843 PDGFRL MTUS1 MIR548V HSALNG0063676 lnc-FGL1-3 RF00017-6858
GH08J017658 Enhancer 1.2 ENCODE CraniofacialAtlas dbSUPER 0.4 +18.9 18916 9 FEZF1 CEBPA ZIC2 FOXA2 SMAD4 SAP130 RXRA CTBP1 RARA ZBTB33 ENSG00000253168 MTUS1 MIR548V HSALNG0063676 lnc-FGL1-3 PDGFRL RF00017-6858
GH08J017668 Enhancer 0.6 Ensembl dbSUPER 0.4 +12.9 12856 0.8 RCOR1 GATA2 POLR2A CHD2 PDGFRL MTUS1 MIR548V HSALNG0063676 lnc-FGL1-3 RF00017-6858
GH08J017650 Enhancer 0.7 Ensembl ENCODE dbSUPER 0.3 +29.1 29054 5.8 POLR2A RBM22 CEBPB MTUS1 PDGFRL HSALNG0063676 MIR548V lnc-FGL1-3 RF00017-6858
GH08J017647 Enhancer 0.7 Ensembl ENCODE dbSUPER 0.3 +33.2 33216 1.9 RBM22 TCF7L2 FOS MTUS1 HSALNG0063676 MIR548V PDGFRL RF00017-6858
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548V on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR548V Gene

Latest Assembly
chr8:17,681,578-17,681,657
(GRCh38/hg38)
Size:
80 bases
Orientation:
Minus strand

Previous Assembly
chr8:17,539,087-17,539,166
(GRCh37/hg19 by Entrez Gene)
Size:
80 bases
Orientation:
Minus strand

chr8:17,539,087-17,539,166
(GRCh37/hg19 by Ensembl)
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR548V Gene

Genes around MIR548V on UCSC Golden Path with GeneCards custom track
MIR548V in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR548V Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548V Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548V Gene

Proteins for MIR548V Gene

Post-translational modifications for MIR548V Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548V Gene

Domains & Families for MIR548V Gene

Gene Families for MIR548V Gene

genes like me logo Genes that share domains with MIR548V: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548V Gene

Function for MIR548V Gene

Phenotypes From GWAS Catalog for MIR548V Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548V Gene

Localization for MIR548V Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548V Gene

Pathways & Interactions for MIR548V Gene

PathCards logo

SuperPathways for MIR548V Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548V Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548V Gene

Drugs & Compounds for MIR548V Gene

No Compound Related Data Available

Transcripts for MIR548V Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR548V Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B80E_9606 precursor_RNA 80 4

RefSeq: NR_036103,

Ensembl: ENST00000584165 (view in UCSC) ,

miRBase: MI0014174,

ENA: LM611000.1:1..80:precursor_RNA,

URS000045E0EC_9606 miRNA 22 4

RefSeq: NR_036103,

miRBase: MIMAT0015020,

TarBase: hsa-miR-548v,

ENA: LM381645.1:1..22:ncRNA, LM611000.1:49..70:ncRNA,

MIR548V in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548V Gene

No ASD Table

Relevant External Links for MIR548V Gene

GeneLoc Exon Structure for
MIR548V

No data available for mRNA/cDNA for MIR548V Gene

Expression for MIR548V Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR548V Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR548V

genes like me logo Genes that share expression patterns with MIR548V: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548V Gene

Orthologs for MIR548V Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548V Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 99 (a)
OneToOne
Species where no ortholog for MIR548V was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR548V Gene

ENSEMBL:
Gene Tree for MIR548V (if available)
TreeFam:
Gene Tree for MIR548V (if available)

Paralogs for MIR548V Gene

No data available for Paralogs for MIR548V Gene

Variants for MIR548V Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR548V Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR548V Gene

Variant ID Type Subtype PubMed ID
esv2759600 CNV loss 17122850
esv34867 CNV loss 17911159
esv3616489 CNV loss 21293372
esv3616492 CNV loss 21293372
nsv831247 CNV gain 17160897
nsv831249 CNV loss 17160897

Additional Variant Information for MIR548V Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548V

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR548V Gene

Disorders for MIR548V Gene

Additional Disease Information for MIR548V

No disorders were found for MIR548V Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548V Gene

Publications for MIR548V Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR548V Gene

Sources for MIR548V Gene