microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548T Gene

Data sources for MIR548T Gene:

Subcategory (RNA class) for MIR548T Gene

miRNA

Aliases for MIR548T Gene

External Ids for MIR548T Gene

Previous GeneCards Identifiers for MIR548T Gene

  • GC04U901359
  • GC04P165301
  • GC04P174191

Summaries for MIR548T Gene

Entrez Gene Summary for MIR548T Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548T Gene

MIR548T (MicroRNA 548t) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548T Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548T Gene

Genomics for MIR548T Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR548T Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J173267 Enhancer 0.3 Ensembl dbSUPER 250.7 -0.5 -459 0.2 MIR548T lnc-HMGB2-2 HMGB2 GALNT7
GH04J173241 Enhancer 0.9 Ensembl ENCODE dbSUPER 11.2 -23.1 -23066 6.2 EBF1 PRDM6 INSM2 JUND SP7 SPI1 OSR2 NANOG FOS RUNX3 MIR548T LOC101930370 GALNT7 lnc-HMGB2-8 lnc-HMGB2-2 HMGB2
GH04J173263 Enhancer 1 ENCODE dbSUPER 0.7 -3.4 -3418 1.7 FEZF1 IKZF1 BHLHE40 VEZF1 TAL1 TAF9B MYNN NKRF PRDM6 SMARCA4 lnc-HMGB2-2 SCRG1 MIR548T HMGB2 GALNT7
GH04J173281 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 +13.9 13866 1.6 MNT IKZF1 REST TRIM25 ZEB2 TAL1 NKRF PRDM10 CTCF SPI1 LOC101930370 HSALNG0038582 MIR548T HMGB2 GALNT7
GH04J173273 Enhancer 0.7 Ensembl ENCODE 0.7 +4.7 4709 1.1 SP7 ZNF629 ATF3 OSR2 GFI1B CEBPB HIC1 ZNF184 SCRG1 LOC101930370 MIR548T HSALNG0038582 HMGB2 GALNT7
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548T on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR548T Gene

Latest Assembly
chr4:173,268,160-173,268,233
(GRCh38/hg38)
Size:
74 bases
Orientation:
Plus strand

Previous Assembly
chr4:174,189,311-174,189,384
(GRCh37/hg19 by Entrez Gene)
Size:
74 bases
Orientation:
Plus strand

chr4:174,189,311-174,189,384
(GRCh37/hg19 by Ensembl)
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR548T Gene

Genes around MIR548T on UCSC Golden Path with GeneCards custom track
MIR548T in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR548T Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548T Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548T Gene

Proteins for MIR548T Gene

Post-translational modifications for MIR548T Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548T Gene

Domains & Families for MIR548T Gene

Gene Families for MIR548T Gene

genes like me logo Genes that share domains with MIR548T: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548T Gene

Function for MIR548T Gene

Phenotypes From GWAS Catalog for MIR548T Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548T Gene

Localization for MIR548T Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548T Gene

Pathways & Interactions for MIR548T Gene

PathCards logo

SuperPathways for MIR548T Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548T Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548T Gene

Drugs & Compounds for MIR548T Gene

No Compound Related Data Available

Transcripts for MIR548T Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR548T Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000012930C_9606 miRNA 25 5

RefSeq: NR_036093, NR_037516, NR_037517,

LncBase: hsa-miR-548aa, hsa-miR-548t-3p,

miRBase: MIMAT0022730,

TarBase: hsa-miR-548aa, hsa-miR-548t-3p,

ENA: LM382187.1:1..25:ncRNA, LM383031.1:1..25:ncRNA, LM610991.1:46..70:ncRNA, LM611270.1:55..79:ncRNA, LM611271.1:55..79:ncRNA,

URS000075BD13_9606 precursor_RNA 74 4

RefSeq: NR_036093,

Ensembl: ENST00000408369 (view in UCSC) ,

miRBase: MI0014164,

ENA: LM610991.1:1..74:precursor_RNA,

URS000057CDAB_9606 miRNA 21 3

RefSeq: NR_036093,

miRBase: MIMAT0015009,

ENA: LM381635.1:1..21:ncRNA, LM610991.1:10..30:ncRNA,

MIR548T in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548T Gene

No ASD Table

Relevant External Links for MIR548T Gene

GeneLoc Exon Structure for
MIR548T

No data available for mRNA/cDNA for MIR548T Gene

Expression for MIR548T Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR548T

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548T Gene

Orthologs for MIR548T Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548T Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 99 (a)
OneToOne
Species where no ortholog for MIR548T was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR548T Gene

ENSEMBL:
Gene Tree for MIR548T (if available)
TreeFam:
Gene Tree for MIR548T (if available)

Paralogs for MIR548T Gene

No data available for Paralogs for MIR548T Gene

Variants for MIR548T Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR548T Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for MIR548T Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548T

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548T Gene

Disorders for MIR548T Gene

Additional Disease Information for MIR548T

No disorders were found for MIR548T Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548T Gene

Publications for MIR548T Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  2. Re-inspection of small RNA sequence datasets reveals several novel human miRNA genes. (PMID: 20532037) Hansen TB … Kjems J (PloS one 2010) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR548T Gene

Sources for MIR548T Gene