microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548Q Gene

Subcategory (RNA class) for MIR548Q Gene

miRNA

Quality Score for this RNA gene is

16

Aliases for MIR548Q Gene

  • MicroRNA 548q 2 3 5
  • Hsa-MiR-548q 168 179
  • Hsa-Mir-548q 3
  • MIMAT0011163 53
  • MI0010637 53
  • MIR548Q 2

External Ids for MIR548Q Gene

Previous GeneCards Identifiers for MIR548Q Gene

  • GC00U929744

Summaries for MIR548Q Gene

Entrez Gene Summary for MIR548Q Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548Q Gene

MIR548Q (MicroRNA 548q) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548Q Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548Q Gene

Genomics for MIR548Q Gene

GeneHancer (GH) Regulatory Elements for MIR548Q Gene

Promoters and enhancers for MIR548Q Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J012724 Enhancer 0.5 Ensembl 750.6 +0.4 352 1.6 MAFK ZNF316 MAFG ZBTB40 MAFF EMSY MIR548Q piR-50444-037 CAMK1D
GH10J012263 Promoter/Enhancer 1.9 FANTOM5 ENCODE CraniofacialAtlas dbSUPER 10.1 +460.4 460398 3.6 SP1 ZBTB40 CTCF ZBTB6 SMARCE1 ZNF362 MYC CC2D1A ETV6 RELA lnc-CDC123-2 CAMK1D UPF2 MIR548Q SEC61A2 piR-57133-040
GH10J012240 Enhancer 1.1 FANTOM5 ENCODE dbSUPER 10.3 +482.1 482081 5.2 SP1 RELA MAX MLLT1 ZBTB33 IKZF1 IKZF2 PKNOX1 DPF2 RFX1 CAMK1D MIR548Q NUDT5 UPF2 SEC61A2 ENSG00000228302 piR-43107-030 CDC123
GH10J012603 Enhancer 1 ENCODE dbSUPER 10.7 +120.1 120108 4.1 FOXA1 TCF7L2 ZNF217 RAD21 MNT NFIB ELF3 SP1 CEBPG POLR2A MIR548Q RF00017-588 MIR4481 CAMK1D
GH10J012698 Enhancer 0.9 Ensembl ENCODE 11.2 +25.5 25469 2.2 NR2F6 HLF RAD21 SP1 HNF1A ZNF384 RXRA FOXA2 FOXK2 TCF7 MIR548Q CCDC3 OPTN piR-50444-037 CAMK1D
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548Q on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548Q Gene

Genomic Locations for MIR548Q Gene
chr10:12,725,254-12,725,353
(GRCh38/hg38)
Size:
100 bases
Orientation:
Minus strand
chr10:12,767,253-12,767,352
(GRCh37/hg19)
Size:
100 bases
Orientation:
Minus strand

Genomic View for MIR548Q Gene

Genes around MIR548Q on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548Q Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548Q Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548Q Gene

Proteins for MIR548Q Gene

Post-translational modifications for MIR548Q Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548Q Gene

Domains & Families for MIR548Q Gene

Gene Families for MIR548Q Gene

genes like me logo Genes that share domains with MIR548Q: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548Q Gene

Function for MIR548Q Gene

Phenotypes From GWAS Catalog for MIR548Q Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548Q Gene

Localization for MIR548Q Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548Q Gene

Pathways & Interactions for MIR548Q Gene

PathCards logo

SuperPathways for MIR548Q Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548Q Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548Q Gene

Drugs & Compounds for MIR548Q Gene

No Compound Related Data Available

Transcripts for MIR548Q Gene

mRNA/cDNA for MIR548Q Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(3) ENA transcripts :
(1) LncBase transcripts :
(1) TarBase transcripts :
(2) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548Q Gene

No ASD Table

Relevant External Links for MIR548Q Gene

GeneLoc Exon Structure for
MIR548Q
ECgene alternative splicing isoforms for
MIR548Q

Expression for MIR548Q Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548Q Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548Q Gene:

MIR548Q
genes like me logo Genes that share expression patterns with MIR548Q: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548Q Gene

Orthologs for MIR548Q Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548Q Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 33
  • 97 (a)
OneToMany
Species where no ortholog for MIR548Q was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548Q Gene

ENSEMBL:
Gene Tree for MIR548Q (if available)
TreeFam:
Gene Tree for MIR548Q (if available)

Paralogs for MIR548Q Gene

No data available for Paralogs for MIR548Q Gene

Variants for MIR548Q Gene

Sequence variations from dbSNP and Humsavar for MIR548Q Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000185186 -- 12,726,535(-) AAAA/AA upstream_transcript_variant
rs1002622198 -- 12,724,947(-) T/C downstream_transcript_variant
rs1004666819 -- 12,725,873(-) C/T upstream_transcript_variant
rs1004710580 -- 12,726,153(-) C/T upstream_transcript_variant
rs1005928482 -- 12,727,152(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR548Q Gene

Variant ID Type Subtype PubMed ID
esv3622363 CNV gain 21293372

Additional Variant Information for MIR548Q Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548Q

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548Q Gene

Disorders for MIR548Q Gene

Additional Disease Information for MIR548Q

No disorders were found for MIR548Q Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548Q Gene

Publications for MIR548Q Gene

  1. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. (PMID: 19390579) Wyman SK … Tewari M (PloS one 2009) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR548Q Gene

Sources for MIR548Q Gene