microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548O2 Gene

Subcategory (RNA class) for MIR548O2 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR548O2 Gene

  • MIR548O2 2 5
  • MIMAT0022738 50
  • MIMAT0022740 50
  • MIMAT0005919 50
  • MIMAT0004806 50
  • MI0016746 50

External Ids for MIR548O2 Gene

Previous GeneCards Identifiers for MIR548O2 Gene

  • GC20U900697
  • GC20P037146

Summaries for MIR548O2 Gene

Entrez Gene Summary for MIR548O2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548O2 Gene

MIR548O2 (MicroRNA 548o-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548O2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548O2 Gene

Genomics for MIR548O2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR548O2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J038523 Enhancer 0.3 Ensembl 0.4 +7.1 7138 1 CEBPB SNHG17 ADIG SNORA71A SNORA71B ENSG00000224635 MIR548O2 RPS3P2 RALGAPB
GH20J038513 Enhancer 0.2 Ensembl 0.7 -2.7 -2662 0.2 SNORA60 SNHG11 ENSG00000201811 SNHG17 SNORA71D SNORA71C MIR548O2 piR-54764-400 RALGAPB ADIG
GH20J038519 Enhancer 0.2 VISTA 0.7 +3.9 3864 1.4 SNHG11 SNORA60 ENSG00000201811 SNHG17 SNORA71D SNORA71C MIR548O2 RPS3P2 RALGAPB ADIG
GH20J038536 Enhancer 0.3 ENCODE 0.4 +20.0 20047 1.2 CTCF RPS3P2 ADIG ARHGAP40 ENSG00000224635 MIR548O2 RALGAPB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548O2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR548O2 Gene

Genomic Locations for MIR548O2 Gene
chr20:38,516,563-38,516,632
(GRCh38/hg38)
Size:
70 bases
Orientation:
Plus strand
chr20:37,145,206-37,145,275
(GRCh37/hg19)
Size:
70 bases
Orientation:
Plus strand

Genomic View for MIR548O2 Gene

Genes around MIR548O2 on UCSC Golden Path with GeneCards custom track
MIR548O2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR548O2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548O2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548O2 Gene

Proteins for MIR548O2 Gene

Post-translational modifications for MIR548O2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548O2 Gene

Domains & Families for MIR548O2 Gene

Gene Families for MIR548O2 Gene

genes like me logo Genes that share domains with MIR548O2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548O2 Gene

Function for MIR548O2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548O2 Gene

Localization for MIR548O2 Gene

Gene Ontology (GO) - Cellular Components for MIR548O2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR548O2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR548O2 Gene

Pathways & Interactions for MIR548O2 Gene

PathCards logo

SuperPathways for MIR548O2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548O2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548O2 Gene

Drugs & Compounds for MIR548O2 Gene

No Compound Related Data Available

Transcripts for MIR548O2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR548O2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075BCBF_9606 precursor_RNA 70 5

HGNC: 41882,

RefSeq: NR_039605,

Ensembl: ENST00000616090 (view in UCSC) ,

miRBase: MI0016746,

ENA: LM611272.1:1..70:precursor_RNA,

URS0000080D0A_9606 miRNA 22 5

RefSeq: NR_031669, NR_039605,

LncBase: hsa-miR-548o-3p,

miRBase: MIMAT0005919,

TarBase: hsa-miR-548o-3p,

ENA: LM380707.1:1..22:ncRNA, LM610155.1:87..108:ncRNA, LM611272.1:45..66:ncRNA,

URS00002C02E4_9606 miRNA 22 5

RefSeq: NR_030347, NR_039605, NR_039762,

LncBase: hsa-miR-548am-5p, hsa-miR-548c-5p, hsa-miR-548o-5p,

miRBase: MIMAT0004806, MIMAT0022738, MIMAT0022740,

TarBase: hsa-miR-548am-5p, hsa-miR-548c-5p, hsa-miR-548o-5p,

ENA: View 6 records in RNAcentral

MIR548O2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548O2 Gene

No ASD Table

Relevant External Links for MIR548O2 Gene

GeneLoc Exon Structure for
MIR548O2

No data available for mRNA/cDNA for MIR548O2 Gene

Expression for MIR548O2 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548O2 Gene

Orthologs for MIR548O2 Gene

Evolution for MIR548O2 Gene

ENSEMBL:
Gene Tree for MIR548O2 (if available)
TreeFam:
Gene Tree for MIR548O2 (if available)

No data available for Orthologs for MIR548O2 Gene

Paralogs for MIR548O2 Gene

No data available for Paralogs for MIR548O2 Gene

Variants for MIR548O2 Gene

Additional dbSNP identifiers (rs#s) for MIR548O2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548O2 Gene

Variant ID Type Subtype PubMed ID
nsv1058457 CNV loss 25217958

Additional Variant Information for MIR548O2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548O2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR548O2 Gene

Disorders for MIR548O2 Gene

No disorders were found for MIR548O2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548O2 Gene

Publications for MIR548O2 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR548O2 Gene

Sources for MIR548O2 Gene