microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548F1 Gene

Subcategory (RNA class) for MIR548F1 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR548F1 Gene

  • MicroRNA 548f-1 2 3 5
  • Hsa-MiR-548f-3p 163 173
  • Hsa-Mir-548f-1 2 3
  • MIR548F1 2 5
  • MIMAT0026739 50
  • MIMAT0005895 50
  • MIR548F-1 3
  • MIRN548F1 3
  • MI0006374 50

External Ids for MIR548F1 Gene

Previous HGNC Symbols for MIR548F1 Gene

  • MIRN548F1

Previous GeneCards Identifiers for MIR548F1 Gene

  • GC00U923015
  • GC10M056038
  • GC10M056367

Summaries for MIR548F1 Gene

Entrez Gene Summary for MIR548F1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548F1 Gene

MIR548F1 (MicroRNA 548f-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548F1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548F1 Gene

Genomics for MIR548F1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR548F1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J054607 Enhancer 0.3 Ensembl 600.7 +0.3 256 0.6 POLR2A MIR548F1 RF01061-027 NEFMP1 LOC105378311 MTRNR2L5
GH10J054606 Enhancer 0.2 Ensembl 600.7 +1.4 1356 0.4 MIR548F1 RF01061-027 NEFMP1 LOC105378311 MTRNR2L5
GH10J054613 Enhancer 0.5 Ensembl 0.4 -5.5 -5544 1.8 NFE2 ZNF316 MAFF MAFK MAFG NFE2L2 JUN MIR548F1 piR-37698-001 LOC105378311 MTRNR2L5
GH10J054621 Enhancer 0.3 Ensembl 0.4 -14.2 -14244 0.4 NR2F2 piR-37698-001 MIR548F1 LOC105378311 MTRNR2L5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548F1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR548F1 Gene

Genomic Locations for MIR548F1 Gene
chr10:54,607,874-54,607,957
(GRCh38/hg38)
Size:
84 bases
Orientation:
Minus strand
chr10:56,367,634-56,367,717
(GRCh37/hg19)
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR548F1 Gene

Genes around MIR548F1 on UCSC Golden Path with GeneCards custom track
MIR548F1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR548F1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548F1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548F1 Gene

Proteins for MIR548F1 Gene

Post-translational modifications for MIR548F1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548F1 Gene

Domains & Families for MIR548F1 Gene

Gene Families for MIR548F1 Gene

genes like me logo Genes that share domains with MIR548F1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548F1 Gene

Function for MIR548F1 Gene

Phenotypes From GWAS Catalog for MIR548F1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548F1 Gene

Localization for MIR548F1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548F1 Gene

Pathways & Interactions for MIR548F1 Gene

PathCards logo

SuperPathways for MIR548F1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548F1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548F1 Gene

Drugs & Compounds for MIR548F1 Gene

No Compound Related Data Available

Transcripts for MIR548F1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR548F1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A845_9606 precursor_RNA 84 5

HGNC: 35305,

RefSeq: NR_031642,

Ensembl: ENST00000408667 (view in UCSC) ,

miRBase: MI0006374,

ENA: LM610135.1:1..84:precursor_RNA,

URS00000B7F84_9606 miRNA 19 5

RefSeq: NR_031642, NR_031643, NR_031644, NR_031645, NR_031646,

LncBase: hsa-miR-548f-3p,

miRBase: MIMAT0005895,

TarBase: hsa-miR-548f-3p,

ENA: View 6 records in RNAcentral

URS000075B630_9606 miRNA 22 3

RefSeq: NR_031642,

miRBase: MIMAT0026739,

ENA: LM610135.1:11..32:ncRNA,

MIR548F1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548F1 Gene

No ASD Table

Relevant External Links for MIR548F1 Gene

GeneLoc Exon Structure for
MIR548F1

No data available for mRNA/cDNA for MIR548F1 Gene

Expression for MIR548F1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR548F1

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548F1 Gene

Orthologs for MIR548F1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548F1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 71 (a)
OneToOne
Species where no ortholog for MIR548F1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR548F1 Gene

ENSEMBL:
Gene Tree for MIR548F1 (if available)
TreeFam:
Gene Tree for MIR548F1 (if available)

Paralogs for MIR548F1 Gene

No data available for Paralogs for MIR548F1 Gene

Variants for MIR548F1 Gene

Additional dbSNP identifiers (rs#s) for MIR548F1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548F1 Gene

Variant ID Type Subtype PubMed ID
dgv1146n54 CNV loss 21841781
esv2750962 CNV loss 17911159
nsv1041917 CNV loss 25217958
nsv1043144 CNV loss 25217958
nsv1045621 CNV gain 25217958
nsv550970 CNV gain 21841781

Additional Variant Information for MIR548F1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548F1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR548F1 Gene

Disorders for MIR548F1 Gene

Additional Disease Information for MIR548F1

No disorders were found for MIR548F1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548F1 Gene

Publications for MIR548F1 Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR548F1 Gene

Sources for MIR548F1 Gene