microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548AX Gene

Data sources for MIR548AX Gene:

RNA type for MIR548AX Gene

miRNA

Aliases for MIR548AX Gene

External Ids for MIR548AX Gene

Previous GeneCards Identifiers for MIR548AX Gene

  • GC0XU901765
  • GC0XM011339

Summaries for MIR548AX Gene

Entrez Gene Summary for MIR548AX Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AX Gene

MIR548AX (MicroRNA 548ax) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AX Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548AX Gene

Genomics for MIR548AX Gene

Genomic Locations for MIR548AX Gene

Latest Assembly
chrX:11,318,614-11,318,686
(GRCh38/hg38)
Size:
73 bases
Orientation:
Minus strand

Previous Assembly
chrX:11,336,734-11,336,806
(GRCh37/hg19 by Entrez Gene)
Size:
73 bases
Orientation:
Minus strand

chrX:11,336,734-11,336,806
(GRCh37/hg19 by Ensembl)
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR548AX Gene

Genes around MIR548AX on UCSC Golden Path with GeneCards custom track
MIR548AX in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR548AX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AX Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR548AX Gene

Proteins for MIR548AX Gene

Post-translational modifications for MIR548AX Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AX Gene

Domains & Families for MIR548AX Gene

Gene Families for MIR548AX Gene

genes like me logo Genes that share domains with MIR548AX: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548AX Gene

Function for MIR548AX Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AX Gene

Localization for MIR548AX Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AX Gene

Pathways & Interactions for MIR548AX Gene

PathCards logo

SuperPathways for MIR548AX Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548AX Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548AX Gene

Drugs & Compounds for MIR548AX Gene

No Compound Related Data Available

Transcripts for MIR548AX Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR548AX Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075D311_9606 miRNA 22 4

RefSeq: NR_049865,

LncBase: hsa-miR-548ax,

miRBase: MIMAT0022474,

TarBase: hsa-miR-548ax,

URS000075A3DD_9606 precursor_RNA 73 3

RefSeq: NR_049865,

Ensembl: ENST00000580117 (view in UCSC) ,

miRBase: MI0019286,

MIR548AX in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AX Gene

No ASD Table

Relevant External Links for MIR548AX Gene

GeneLoc Exon Structure for
MIR548AX

No data available for mRNA/cDNA for MIR548AX Gene

Expression for MIR548AX Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AX Gene

Orthologs for MIR548AX Gene

Evolution for MIR548AX Gene

ENSEMBL:
Gene Tree for MIR548AX (if available)
TreeFam:
Gene Tree for MIR548AX (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR548AX

No data available for Orthologs for MIR548AX Gene

Paralogs for MIR548AX Gene

No data available for Paralogs for MIR548AX Gene

Variants for MIR548AX Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR548AX Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR548AX Gene

Variant ID Type Subtype PubMed ID
esv2739963 CNV deletion 23290073

Additional Variant Information for MIR548AX Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AX
Leiden Open Variation Database (LOVD)
MIR548AX

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR548AX Gene

Disorders for MIR548AX Gene

Additional Disease Information for MIR548AX

No disorders were found for MIR548AX Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AX Gene

Publications for MIR548AX Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR548AX Gene

Sources for MIR548AX Gene