microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548AU Gene

Subcategory (RNA class) for MIR548AU Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR548AU Gene

  • MicroRNA 548au 2 3 5
  • Hsa-MiR-548au-5p 163 173
  • Hsa-MiR-548au-3p 163 173
  • Hsa-Mir-548au 2 3
  • MIR548AU 2 5
  • MIMAT0022291 50
  • MIMAT0022292 50
  • MI0019145 50

External Ids for MIR548AU Gene

Previous GeneCards Identifiers for MIR548AU Gene

  • GC09U901752

Summaries for MIR548AU Gene

Entrez Gene Summary for MIR548AU Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AU Gene

MIR548AU (MicroRNA 548au) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AU Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548AU Gene

Genomics for MIR548AU Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR548AU Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J093585 Enhancer 1.4 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 -4.7 -4740 9.8 GATAD2A CTCF RFX1 IKZF1 RCOR2 JUND GABPA ZIC2 PKNOX1 IRF2 RNU6-829P FAM120A FAM120AOS MIR548AU PHF2 BARX1
GH09J093574 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -18.0 -18038 4.3 HNRNPL PRDM10 IKZF1 BACH1 ZHX2 FOXA1 LARP7 PRDM1 POLR2A PATZ1 PHF2 lnc-FAM120AOS-5 MIR548AU BARX1
GH09J093595 Enhancer 1 Ensembl ENCODE dbSUPER 0.7 +4.1 4060 6.6 TARDBP FOXA1 ZIC2 ZNF24 SCRT2 ZKSCAN1 ZNF316 ATF2 NONO ZNF207 RNU6-829P WNK2 MIR548AU PHF2 RF00017-7722 BARX1
GH09J093580 Enhancer 0.8 ENCODE dbSUPER 0.4 -13.2 -13197 2.5 RFX1 PKNOX1 FOXA2 SAP130 CEBPG TFAP4 ARID4B ZEB2 KDM1A TEAD3 PHF2 MIR548AU BARX1
GH09J093611 Enhancer 0.7 Ensembl dbSUPER 0.4 +18.3 18260 3 SCRT2 DPF2 TCF12 SCRT1 NR2F2 NR2F1 SPI1 NR2F6 RXRA BHLHE40 ENSG00000232063 MIR548AU RF00017-7722 PHF2 BARX1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548AU on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR548AU Gene

Genomic Locations for MIR548AU Gene
chr9:93,594,841-93,594,894
(GRCh38/hg38)
Size:
54 bases
Orientation:
Plus strand

Genomic View for MIR548AU Gene

Genes around MIR548AU on UCSC Golden Path with GeneCards custom track
MIR548AU in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR548AU Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AU Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AU Gene

Proteins for MIR548AU Gene

Post-translational modifications for MIR548AU Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AU Gene

Domains & Families for MIR548AU Gene

Gene Families for MIR548AU Gene

genes like me logo Genes that share domains with MIR548AU: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548AU Gene

Function for MIR548AU Gene

Phenotypes From GWAS Catalog for MIR548AU Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AU Gene

Localization for MIR548AU Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AU Gene

Pathways & Interactions for MIR548AU Gene

PathCards logo

SuperPathways for MIR548AU Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548AU Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548AU Gene

Drugs & Compounds for MIR548AU Gene

No Compound Related Data Available

Transcripts for MIR548AU Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR548AU Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B121_9606 precursor_RNA 54 5

HGNC: 43483,

RefSeq: NR_049853,

Ensembl: ENST00000637016 (view in UCSC) ,

miRBase: MI0019145,

ENA: LM611572.1:1..54:precursor_RNA,

URS000075AEA5_9606 miRNA 21 5

RefSeq: NR_049853,

LncBase: hsa-miR-548au-3p,

miRBase: MIMAT0022292,

TarBase: hsa-miR-548au-3p,

ENA: LM611572.1:34..54:ncRNA,

URS000075CAF3_9606 miRNA 21 5

RefSeq: NR_049853,

LncBase: hsa-miR-548au-5p,

miRBase: MIMAT0022291,

TarBase: hsa-miR-548au-5p,

ENA: LM382960.1:1..21:ncRNA, LM611572.1:1..21:ncRNA,

MIR548AU in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AU Gene

No ASD Table

Relevant External Links for MIR548AU Gene

GeneLoc Exon Structure for
MIR548AU

No data available for mRNA/cDNA for MIR548AU Gene

Expression for MIR548AU Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AU Gene

Orthologs for MIR548AU Gene

Evolution for MIR548AU Gene

ENSEMBL:
Gene Tree for MIR548AU (if available)
TreeFam:
Gene Tree for MIR548AU (if available)

No data available for Orthologs for MIR548AU Gene

Paralogs for MIR548AU Gene

No data available for Paralogs for MIR548AU Gene

Variants for MIR548AU Gene

Additional dbSNP identifiers (rs#s) for MIR548AU Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548AU Gene

Variant ID Type Subtype PubMed ID
dgv19n6 CNV deletion 16902084
dgv4034n100 CNV gain 25217958
dgv6988n54 CNV loss 21841781
esv1223356 CNV deletion 17803354
esv2164871 CNV deletion 18987734
esv23336 CNV loss 19812545
esv2540661 CNV deletion 19546169
esv2671579 CNV deletion 23128226
esv2674728 CNV deletion 23128226
esv2676455 CNV deletion 23128226
esv2720482 CNV deletion 23290073
esv2720493 CNV deletion 23290073
esv2762271 CNV loss 21179565
esv3305769 CNV mobile element insertion 20981092
esv3372818 CNV insertion 20981092
esv3559910 CNV deletion 23714750
esv3591887 CNV loss 21293372
esv3591888 CNV loss 21293372
esv3591890 CNV loss 21293372
esv9107 CNV loss 19470904
esv990602 CNV deletion 20482838
nsv1071610 CNV deletion 25765185
nsv1114124 CNV deletion 24896259
nsv1152379 CNV deletion 26484159
nsv1160839 CNV deletion 26073780
nsv213203 CNV deletion 16902084
nsv2870 CNV deletion 18451855
nsv471617 CNV gain 15918152
nsv480289 CNV novel sequence insertion 20440878
nsv507026 OTHER sequence alteration 20534489
nsv509311 CNV insertion 20534489
nsv528330 CNV gain 19592680
nsv824984 CNV gain 20364138
nsv955052 CNV deletion 24416366

Additional Variant Information for MIR548AU Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AU

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR548AU Gene

Disorders for MIR548AU Gene

Additional Disease Information for MIR548AU

No disorders were found for MIR548AU Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AU Gene

Publications for MIR548AU Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR548AU Gene

Sources for MIR548AU Gene