microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548AQ Gene

Subcategory (RNA class) for MIR548AQ Gene

miRNA

Number of RNA Genes sources:

2 / 14

Aliases for MIR548AQ Gene

  • MicroRNA 548aq 2 3 5
  • Hsa-Mir-548aq 3
  • MIMAT0022264 51
  • MIMAT0022263 51
  • MI0019130 51
  • MIR548AQ 2

External Ids for MIR548AQ Gene

Previous GeneCards Identifiers for MIR548AQ Gene

  • GC03U901815
  • GC03M185486

Summaries for MIR548AQ Gene

Entrez Gene Summary for MIR548AQ Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AQ Gene

MIR548AQ (MicroRNA 548aq) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AQ Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548AQ Gene

Genomics for MIR548AQ Gene

GeneHancer (GH) Regulatory Elements for MIR548AQ Gene

Promoters and enhancers for MIR548AQ Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J185768 Enhancer 0.9 ENCODE dbSUPER 500.7 -0.8 -784 0.2 CTCF USF1 REST CUX1 USF2 TOE1 MYC RAD21 TRIM22 SMC3 MIR548AQ piR-38580-214 IGF2BP2-AS1 IGF2BP2 lnc-TRA2B-2 lnc-SENP2-1
GH03J185766 Enhancer 0.4 dbSUPER 500.7 +0.9 860 1.3 ZBTB40 CTCF GATA2 ESRRA MIR548AQ piR-38580-214 IGF2BP2 IGF2BP2-AS1 lnc-SENP2-6 lnc-TRA2B-2 lnc-SENP2-1
GH03J185762 Enhancer 0.8 FANTOM5 ENCODE 0.7 +3.7 3684 2.9 ZNF10 SCRT1 MEIS2 EGR2 FOS ARHGAP35 PKNOX1 ZEB2 SP7 ZNF629 IGF2BP2-AS1 MIR548AQ lnc-SENP2-6 lnc-TRA2B-2 IGF2BP2 lnc-SENP2-1
GH03J185744 Enhancer 1.1 VISTA ENCODE dbSUPER 0.4 +21.9 21944 3.2 NCOR1 FOS TCF7 SKI OSR2 BCL11A SAP130 ZFHX2 CREM SMAD4 IGF2BP2-AS1 VPS8 lnc-SENP2-6 MIR548AQ IGF2BP2 lnc-TRA2B-2 lnc-SENP2-1
GH03J185757 Enhancer 0.7 ENCODE dbSUPER 0.4 +9.2 9187 2.3 PBX2 RBM22 FOXA1 ZFP91 SCRT1 ZNF664 MEIS2 PKNOX1 HMBOX1 PRDM1 IGF2BP2-AS1 MIR548AQ lnc-SENP2-6 IGF2BP2 lnc-TRA2B-2 lnc-SENP2-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548AQ on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AQ Gene

Genomic Locations for MIR548AQ Gene
chr3:185,767,847-185,767,904
(GRCh38/hg38)
Size:
58 bases
Orientation:
Minus strand
chr3:185,485,635-185,485,692
(GRCh37/hg19)
Size:
58 bases
Orientation:
Minus strand

Genomic View for MIR548AQ Gene

Genes around MIR548AQ on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AQ Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AQ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AQ Gene

Proteins for MIR548AQ Gene

Post-translational modifications for MIR548AQ Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AQ Gene

Domains & Families for MIR548AQ Gene

Gene Families for MIR548AQ Gene

genes like me logo Genes that share domains with MIR548AQ: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548AQ Gene

Function for MIR548AQ Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AQ Gene

Localization for MIR548AQ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AQ Gene

Pathways & Interactions for MIR548AQ Gene

PathCards logo

SuperPathways for MIR548AQ Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR548AQ Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548AQ Gene

Drugs & Compounds for MIR548AQ Gene

No Compound Related Data Available

Transcripts for MIR548AQ Gene

mRNA/cDNA for MIR548AQ Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
4 ENA transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AQ Gene

No ASD Table

Relevant External Links for MIR548AQ Gene

GeneLoc Exon Structure for
MIR548AQ

Expression for MIR548AQ Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AQ Gene

Orthologs for MIR548AQ Gene

Evolution for MIR548AQ Gene

ENSEMBL:
Gene Tree for MIR548AQ (if available)
TreeFam:
Gene Tree for MIR548AQ (if available)

No data available for Orthologs for MIR548AQ Gene

Paralogs for MIR548AQ Gene

No data available for Paralogs for MIR548AQ Gene

Variants for MIR548AQ Gene

Additional dbSNP identifiers (rs#s) for MIR548AQ Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548AQ Gene

Variant ID Type Subtype PubMed ID
nsv1053272 CNV gain 25217958

Additional Variant Information for MIR548AQ Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AQ

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR548AQ Gene

Disorders for MIR548AQ Gene

Additional Disease Information for MIR548AQ

No disorders were found for MIR548AQ Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AQ Gene

Publications for MIR548AQ Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR548AQ Gene

Sources for MIR548AQ Gene