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Aliases for MIR548AP Gene

Subcategory (RNA class) for MIR548AP Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AP Gene

  • MicroRNA 548ap 2 3 5
  • Hsa-Mir-548ap 3

External Ids for MIR548AP Gene

Previous GeneCards Identifiers for MIR548AP Gene

  • GC15U901416
  • GC15P086369

Summaries for MIR548AP Gene

Entrez Gene Summary for MIR548AP Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AP Gene

MIR548AP (MicroRNA 548ap) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AP Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AP Gene

Genomics for MIR548AP Gene

GeneHancer (GH) Regulatory Elements for MIR548AP Gene

Promoters and enhancers for MIR548AP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I085825 Enhancer 0.7 ENCODE 550.8 +0.2 210 0 PKNOX1 SIN3A CTBP1 GATA3 RCOR1 SMARCE1 MAZ ZNF687 ZNF10 MNT MIR548AP KLHL25 LOC105370952
GH15I085824 Enhancer 0.5 ENCODE 550.8 -0.4 -360 0.8 SREBF1 ZNF217 ZNF10 MNT ZBTB40 MIR548AP KLHL25 ENSG00000259407 RNU6-231P
GH15I085831 Enhancer 0.6 ENCODE 0.4 +6.1 6050 0.2 CTCF ZNF654 RXRA ZNF189 HLF ARID4B BACH1 REST RAD21 ZNF143 KLHL25 MIR1276 LOC105370952 MIR548AP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR548AP on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AP Gene

Genomic Locations for MIR548AP Gene
chr15:85,825,635-85,825,730
(GRCh38/hg38)
Size:
96 bases
Orientation:
Plus strand
chr15:86,368,866-86,368,961
(GRCh37/hg19)

Genomic View for MIR548AP Gene

Genes around MIR548AP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AP Gene

Proteins for MIR548AP Gene

Post-translational modifications for MIR548AP Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AP Gene

Domains & Families for MIR548AP Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AP Gene

Function for MIR548AP Gene

Phenotypes From GWAS Catalog for MIR548AP Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AP Gene

Localization for MIR548AP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AP Gene

Pathways & Interactions for MIR548AP Gene

SuperPathways for MIR548AP Gene

No Data Available

Interacting Proteins for MIR548AP Gene

Gene Ontology (GO) - Biological Process for MIR548AP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AP Gene

Drugs & Compounds for MIR548AP Gene

No Compound Related Data Available

Transcripts for MIR548AP Gene

mRNA/cDNA for MIR548AP Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AP Gene

No ASD Table

Relevant External Links for MIR548AP Gene

GeneLoc Exon Structure for
MIR548AP
ECgene alternative splicing isoforms for
MIR548AP

Expression for MIR548AP Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AP Gene:

MIR548AP
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AP Gene

Orthologs for MIR548AP Gene

Evolution for MIR548AP Gene

ENSEMBL:
Gene Tree for MIR548AP (if available)
TreeFam:
Gene Tree for MIR548AP (if available)

No data available for Orthologs for MIR548AP Gene

Paralogs for MIR548AP Gene

No data available for Paralogs for MIR548AP Gene

Variants for MIR548AP Gene

Sequence variations from dbSNP and Humsavar for MIR548AP Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000197819 -- 85,823,693(+) C/T upstream_transcript_variant
rs1000426424 -- 85,825,779(+) A/T downstream_transcript_variant
rs1000923001 -- 85,826,032(+) G/A downstream_transcript_variant
rs1001102293 -- 85,824,043(+) TTTT/TTT upstream_transcript_variant
rs1001133396 -- 85,824,389(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR548AP Gene

Variant ID Type Subtype PubMed ID
nsv1042976 CNV gain 25217958
esv3637127 CNV gain 21293372
esv3637125 CNV gain 21293372
esv33019 CNV loss 17666407

Additional Variant Information for MIR548AP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AP Gene

Disorders for MIR548AP Gene

Additional Disease Information for MIR548AP

No disorders were found for MIR548AP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AP Gene

Publications for MIR548AP Gene

  1. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3 58
  2. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. (PMID: 17903295) Lunetta KL … Murabito JM (BMC medical genetics 2007) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR548AP Gene

Sources for MIR548AP Gene

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