microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548AK Gene

Subcategory (RNA class) for MIR548AK Gene


Quality Score for this RNA gene is


Aliases for MIR548AK Gene

  • MicroRNA 548ak 2 3 5
  • Hsa-MiR-548ak 168 179
  • Hsa-Mir-548ak 3
  • MIMAT0019013 53
  • MI0016840 53
  • MIR548AK 2

External Ids for MIR548AK Gene

Previous GeneCards Identifiers for MIR548AK Gene

  • GC10U901557
  • GC10P080511
  • GC10M012173

Summaries for MIR548AK Gene

Entrez Gene Summary for MIR548AK Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AK Gene

MIR548AK (MicroRNA 548ak) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AK Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548AK Gene

Genomics for MIR548AK Gene

GeneHancer (GH) Regulatory Elements for MIR548AK Gene

Promoters and enhancers for MIR548AK Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J012128 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 750.6 +1.3 1315 2.6 CTCF MLX POLR2A CTBP1 L3MBTL2 RAD21 ZNF121 MNT ZNF148 NKRF SEC61A2 MIR548AK DHTKD1 UPF2 NUDT5 piR-43951
GH10J012132 Enhancer 0.2 Ensembl 750.6 -1.8 -1785 0.4 MIR548AK SEC61A2 DHTKD1 RF01210-043
GH10J012135 Enhancer 0.2 ENCODE 0.6 -5.0 -4981 0.2 MIR548AK SEC61A2 RF01210-043
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548AK on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AK Gene

Genomic Locations for MIR548AK Gene
57 bases
Minus strand
57 bases
Minus strand

Genomic View for MIR548AK Gene

Genes around MIR548AK on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AK Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AK Gene

Proteins for MIR548AK Gene

Post-translational modifications for MIR548AK Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AK Gene

Domains & Families for MIR548AK Gene

Gene Families for MIR548AK Gene

genes like me logo Genes that share domains with MIR548AK: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548AK Gene

Function for MIR548AK Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AK Gene

Localization for MIR548AK Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AK Gene

Pathways & Interactions for MIR548AK Gene

PathCards logo

SuperPathways for MIR548AK Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548AK Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548AK Gene

Drugs & Compounds for MIR548AK Gene

No Compound Related Data Available

Transcripts for MIR548AK Gene

mRNA/cDNA for MIR548AK Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :
(1) TarBase transcripts :
(3) ENA transcripts :
(1) LncBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AK Gene

No ASD Table

Relevant External Links for MIR548AK Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AK Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AK Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AK Gene

Orthologs for MIR548AK Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AK Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 33
  • 96 (a)
Species where no ortholog for MIR548AK was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AK Gene

Gene Tree for MIR548AK (if available)
Gene Tree for MIR548AK (if available)

Paralogs for MIR548AK Gene

No data available for Paralogs for MIR548AK Gene

Variants for MIR548AK Gene

Sequence variations from dbSNP and Humsavar for MIR548AK Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000525151 -- 12,132,336(-) A/T upstream_transcript_variant
rs1000719988 -- 12,132,364(-) A/G upstream_transcript_variant
rs1002140052 -- 12,130,793(-) C/T non_coding_transcript_variant
rs1004778863 -- 12,131,313(-) G/A/C upstream_transcript_variant
rs1005435972 -- 12,130,384(-) A/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR548AK Gene

Variant ID Type Subtype PubMed ID
dgv673n100 CNV gain 25217958
dgv674n100 CNV gain 25217958
nsv1035709 CNV gain 25217958

Additional Variant Information for MIR548AK Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AK Gene

Disorders for MIR548AK Gene

Additional Disease Information for MIR548AK

No disorders were found for MIR548AK Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AK Gene

Publications for MIR548AK Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR548AK Gene

Sources for MIR548AK Gene