microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548AJ2 Gene

Subcategory (RNA class) for MIR548AJ2 Gene

miRNA

Number of RNA Genes sources:

3 / 14

Aliases for MIR548AJ2 Gene

  • MicroRNA 548aj-2 2 3 5
  • Hsa-Mir-548aj-2 3
  • MIMAT0022739 51
  • MIMAT0022722 51
  • MIMAT0018990 51
  • MIMAT0022733 51
  • MIR548AJ2 2
  • MI0016815 51
  • RF01061 172

External Ids for MIR548AJ2 Gene

Previous GeneCards Identifiers for MIR548AJ2 Gene

  • GC0XU901747
  • GC0XM037885

Summaries for MIR548AJ2 Gene

Entrez Gene Summary for MIR548AJ2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AJ2 Gene

MIR548AJ2 (MicroRNA 548aj-2) is an RNA Gene, and is affiliated with the miRNA class.

Rfam classification for MIR548AJ2 Gene

Additional gene information for MIR548AJ2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR548AJ2 Gene

Genomics for MIR548AJ2 Gene

GeneHancer (GH) Regulatory Elements for MIR548AJ2 Gene

Promoters and enhancers for MIR548AJ2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ038051 Enhancer 0.8 Ensembl ENCODE 13.4 -28.3 -28315 1.4 FOS TRIM28 EP300 OSR2 ZNF184 FOSL2 CEBPB JUN FOSL1 MAFK MIR548AJ2 SYTL5 RF00951-165 ENSG00000250349
GH0XJ038055 Enhancer 0.5 Ensembl 13.4 -31.3 -31315 1 OSR2 ZNF335 ZBTB48 IKZF3 PRDM6 ZNF687 PRDM10 MZF1 ZNF121 SYTL5 MIR548AJ2 RF00951-165 ENSG00000250349
GH0XJ038061 Enhancer 1.1 Ensembl ENCODE 0.3 -37.7 -37714 1.4 ZSCAN5C JUND FOS ZNF639 ZNF354C ZNF10 ZIC2 TRIM28 KLF7 ZNF662 TSPAN7 SYTL5 RF00951-165 MIR548AJ2 ENSG00000250349
GH0XJ038060 Enhancer 0.8 Ensembl 0.3 -36.6 -36615 0.4 ZSCAN5C ZNF639 ZNF662 ATF2 ZNF148 OSR2 BCL11A WT1 SP2 ZBTB17 SYTL5 RF00951-165 MIR548AJ2 ENSG00000250349
GH0XJ038046 Enhancer 0.6 Ensembl 0.4 -21.9 -21915 0.2 ZNF639 TCF7L2 OVOL3 ZNF843 PRDM6 KLF10 GATA3 ZNF449 ZEB2 ZNF629 MIR548AJ2 RF00951-165 SYTL5 ENSG00000250349
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548AJ2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AJ2 Gene

Genomic Locations for MIR548AJ2 Gene
chrX:38,023,895-38,023,986
(GRCh38/hg38)
Size:
92 bases
Orientation:
Minus strand
chrX:37,883,148-37,883,239
(GRCh37/hg19)
Size:
92 bases
Orientation:
Minus strand

Genomic View for MIR548AJ2 Gene

Genes around MIR548AJ2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AJ2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AJ2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AJ2 Gene

Proteins for MIR548AJ2 Gene

Post-translational modifications for MIR548AJ2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AJ2 Gene

Domains & Families for MIR548AJ2 Gene

Gene Families for MIR548AJ2 Gene

genes like me logo Genes that share domains with MIR548AJ2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548AJ2 Gene

Function for MIR548AJ2 Gene

Phenotypes From GWAS Catalog for MIR548AJ2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AJ2 Gene

Localization for MIR548AJ2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AJ2 Gene

Pathways & Interactions for MIR548AJ2 Gene

PathCards logo

SuperPathways for MIR548AJ2 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR548AJ2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548AJ2 Gene

Drugs & Compounds for MIR548AJ2 Gene

No Compound Related Data Available

Transcripts for MIR548AJ2 Gene

mRNA/cDNA for MIR548AJ2 Gene

4 RNACentral transcripts :
4 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
5 miRBase transcripts :
8 ENA transcripts :
1 Rfam transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AJ2 Gene

No ASD Table

Relevant External Links for MIR548AJ2 Gene

GeneLoc Exon Structure for
MIR548AJ2

Expression for MIR548AJ2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR548AJ2

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AJ2 Gene

Orthologs for MIR548AJ2 Gene

Evolution for MIR548AJ2 Gene

ENSEMBL:
Gene Tree for MIR548AJ2 (if available)
TreeFam:
Gene Tree for MIR548AJ2 (if available)

No data available for Orthologs for MIR548AJ2 Gene

Paralogs for MIR548AJ2 Gene

No data available for Paralogs for MIR548AJ2 Gene

Variants for MIR548AJ2 Gene

Additional dbSNP identifiers (rs#s) for MIR548AJ2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548AJ2 Gene

Variant ID Type Subtype PubMed ID
dgv2277e212 CNV loss 25503493
esv2752323 CNV gain 17911159
nsv518029 CNV gain 19592680
nsv519012 CNV gain 19592680

Additional Variant Information for MIR548AJ2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AJ2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR548AJ2 Gene

Disorders for MIR548AJ2 Gene

Additional Disease Information for MIR548AJ2

No disorders were found for MIR548AJ2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AJ2 Gene

Publications for MIR548AJ2 Gene

  1. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) Schizophrenia Working Group of the Psychiatric Genomics Consortium (Nature 2014) 3 54
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 54
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR548AJ2 Gene

Sources for MIR548AJ2 Gene