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Aliases for MIR548AJ1 Gene

Subcategory (RNA class) for MIR548AJ1 Gene


Quality Score for this RNA gene is


Aliases for MIR548AJ1 Gene

  • MicroRNA 548aj-1 2 3 5
  • Hsa-Mir-548aj-1 3

External Ids for MIR548AJ1 Gene

Previous GeneCards Identifiers for MIR548AJ1 Gene

  • GC06U902229
  • GC06M132437

Summaries for MIR548AJ1 Gene

Entrez Gene Summary for MIR548AJ1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AJ1 Gene

MIR548AJ1 (MicroRNA 548aj-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AJ1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AJ1 Gene

Genomics for MIR548AJ1 Gene

GeneHancer (GH) Regulatory Elements for MIR548AJ1 Gene

Promoters and enhancers for MIR548AJ1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I132115 Enhancer 0.5 Ensembl ENCODE 550.8 -0.8 -805 0.7 PKNOX1 MIR548AJ1 ENSG00000280155 GC06M132077
GH06I132121 Enhancer 0.9 ENCODE dbSUPER 0.4 -7.4 -7350 2.6 SOX13 FOXA2 ZBTB21 INSM2 FEZF1 ZIC2 RARA GLI2 ZSCAN5C NR2F6 ENSG00000280155 MIR548AJ1 GC06M132077
GH06I132082 Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +29.9 29906 4.9 PKNOX1 JUN BATF GATA3 JUND KLF16 POLR2A CEBPA FOS ENSG00000236166 LINC01013 AKAP7 MIR548AJ1 GC06M132077
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR548AJ1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AJ1 Gene

Genomic Locations for MIR548AJ1 Gene
72 bases
Minus strand

Genomic View for MIR548AJ1 Gene

Genes around MIR548AJ1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AJ1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AJ1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AJ1 Gene

Proteins for MIR548AJ1 Gene

Post-translational modifications for MIR548AJ1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AJ1 Gene

Domains & Families for MIR548AJ1 Gene

Gene Families for MIR548AJ1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AJ1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AJ1 Gene

Function for MIR548AJ1 Gene

Phenotypes From GWAS Catalog for MIR548AJ1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AJ1 Gene

Localization for MIR548AJ1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AJ1 Gene

Pathways & Interactions for MIR548AJ1 Gene

SuperPathways for MIR548AJ1 Gene

No Data Available

Interacting Proteins for MIR548AJ1 Gene

Gene Ontology (GO) - Biological Process for MIR548AJ1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548AJ1 Gene

Drugs & Compounds for MIR548AJ1 Gene

No Compound Related Data Available

Transcripts for MIR548AJ1 Gene

mRNA/cDNA for MIR548AJ1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AJ1 Gene

No ASD Table

Relevant External Links for MIR548AJ1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AJ1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AJ1 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AJ1 Gene

Orthologs for MIR548AJ1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AJ1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 100 (a)
Species where no ortholog for MIR548AJ1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AJ1 Gene

Gene Tree for MIR548AJ1 (if available)
Gene Tree for MIR548AJ1 (if available)

Paralogs for MIR548AJ1 Gene

No data available for Paralogs for MIR548AJ1 Gene

Variants for MIR548AJ1 Gene

Sequence variations from dbSNP and Humsavar for MIR548AJ1 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000280635 -- 132,117,233(-) C/A upstream_transcript_variant
rs1000734066 -- 132,116,995(-) T/C upstream_transcript_variant
rs1001335835 -- 132,115,567(-) A/G upstream_transcript_variant
rs1001682456 -- 132,115,924(-) A/G upstream_transcript_variant
rs1003281149 -- 132,115,562(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR548AJ1 Gene

Variant ID Type Subtype PubMed ID
esv3610830 CNV gain 21293372
esv2762616 CNV gain 21179565

Additional Variant Information for MIR548AJ1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AJ1 Gene

Disorders for MIR548AJ1 Gene

Additional Disease Information for MIR548AJ1

No disorders were found for MIR548AJ1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AJ1 Gene

Publications for MIR548AJ1 Gene

  1. Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1. (PMID: 25147182) Thompson JW … Luchansky SJ (The Journal of biological chemistry 2014) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR548AJ1 Gene

Sources for MIR548AJ1 Gene

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