microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR548AH Gene

Subcategory (RNA class) for MIR548AH Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR548AH Gene

  • MicroRNA 548ah 2 3 5
  • Hsa-Mir-548ah 2 3
  • MIR548AH 2 5
  • MIMAT0020957 50
  • MIMAT0018972 50
  • MI0016796 50

External Ids for MIR548AH Gene

Previous GeneCards Identifiers for MIR548AH Gene

  • GC04U901498
  • GC04P077499

Summaries for MIR548AH Gene

Entrez Gene Summary for MIR548AH Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AH Gene

MIR548AH (MicroRNA 548ah) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AH Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR548AH Gene

Genomics for MIR548AH Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR548AH Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J076579 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +5.6 5550 4.2 ZNF692 FOXA1 ZNF501 ZNF341 SCRT2 ZBTB44 TCF7L2 OSR2 ZBTB17 SCRT1 SHROOM3 RNU6-145P ENSG00000233860 CXCL9 MIR548AH lnc-STBD1-5 SOWAHB
GH04J076578 Enhancer 0.3 Ensembl 0.7 +2.8 2750 0.2 HNF4A SP1 RNU6-145P ENSG00000233860 SHROOM3 MIR548AH lnc-STBD1-5 SOWAHB
GH04J076580 Enhancer 0.3 Ensembl 0.7 +3.2 3150 0.2 ZBTB40 RNU6-145P ENSG00000233860 SHROOM3 MIR548AH lnc-STBD1-5 SOWAHB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR548AH on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR548AH Gene

Genomic Locations for MIR548AH Gene
chr4:76,575,551-76,575,626
(GRCh38/hg38)
Size:
76 bases
Orientation:
Plus strand
chr4:77,496,704-77,496,779
(GRCh37/hg19)
Size:
76 bases
Orientation:
Plus strand

Genomic View for MIR548AH Gene

Genes around MIR548AH on UCSC Golden Path with GeneCards custom track
MIR548AH in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR548AH Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AH Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AH Gene

Proteins for MIR548AH Gene

Post-translational modifications for MIR548AH Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AH Gene

Domains & Families for MIR548AH Gene

Gene Families for MIR548AH Gene

genes like me logo Genes that share domains with MIR548AH: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR548AH Gene

Function for MIR548AH Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AH Gene

Localization for MIR548AH Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AH Gene

Pathways & Interactions for MIR548AH Gene

PathCards logo

SuperPathways for MIR548AH Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR548AH Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR548AH Gene

Drugs & Compounds for MIR548AH Gene

No Compound Related Data Available

Transcripts for MIR548AH Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR548AH Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075CCBF_9606 precursor_RNA 76 4

HGNC: 41605,

RefSeq: NR_039655,

Ensembl: ENST00000637109 (view in UCSC) ,

miRBase: MI0016796,

URS0000462CE4_9606 miRNA 22 2

RefSeq: NR_039655,

miRBase: MIMAT0020957,

URS0000759B5E_9606 miRNA 20 2

RefSeq: NR_039655,

miRBase: MIMAT0018972,

MIR548AH in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AH Gene

No ASD Table

Relevant External Links for MIR548AH Gene

GeneLoc Exon Structure for
MIR548AH

No data available for mRNA/cDNA for MIR548AH Gene

Expression for MIR548AH Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AH Gene

Orthologs for MIR548AH Gene

Evolution for MIR548AH Gene

ENSEMBL:
Gene Tree for MIR548AH (if available)
TreeFam:
Gene Tree for MIR548AH (if available)

No data available for Orthologs for MIR548AH Gene

Paralogs for MIR548AH Gene

No data available for Paralogs for MIR548AH Gene

Variants for MIR548AH Gene

Additional dbSNP identifiers (rs#s) for MIR548AH Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548AH Gene

Variant ID Type Subtype PubMed ID
nsv594696 CNV gain 21841781
nsv7363 OTHER inversion 18451855

Additional Variant Information for MIR548AH Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AH

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR548AH Gene

Disorders for MIR548AH Gene

Additional Disease Information for MIR548AH

No disorders were found for MIR548AH Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AH Gene

Publications for MIR548AH Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3
  2. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR548AH Gene

Sources for MIR548AH Gene