microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR544A Gene

Subcategory (RNA class) for MIR544A Gene

miRNA

Number of RNA Genes sources:

5 / 17

Aliases for MIR544A Gene

  • MicroRNA 544a 2 3 5
  • Hsa-Mir-544 2 3 178
  • MicroRNA 544 2 3
  • Hsa-MiR-544a 163 173
  • MIR544A 2 5
  • Hsa-Mir-544a 3
  • MIMAT0003164 50
  • MI0003515 50
  • MIRN544 3
  • RF01045 168
  • MIR544 3

External Ids for MIR544A Gene

Previous HGNC Symbols for MIR544A Gene

  • MIRN544
  • MIR544

Previous GeneCards Identifiers for MIR544A Gene

  • GC14P101746
  • GC14P101785
  • GC14P101846
  • GC14P101987
  • GC14P102185
  • GC14P101260
  • GC14P101871
  • GC14P103640
  • GC14P103859
  • GC14P104135
  • GC14P104476
  • GC14P102190
  • GC14P102359
  • GC14P102530
  • GC14P102709
  • GC14P102882
  • GC14P103055
  • GC14P103250
  • GC14P103457

Summaries for MIR544A Gene

Entrez Gene Summary for MIR544A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR544A Gene

MIR544A (MicroRNA 544a) is an RNA Gene, and is affiliated with the miRNA class.

Rfam classification for MIR544A Gene

Additional gene information for MIR544A Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR544A Gene

Genomics for MIR544A Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR544A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR544A on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR544A Gene

Genomic Locations for MIR544A Gene
chr14:101,048,658-101,048,748
(GRCh38/hg38)
Size:
91 bases
Orientation:
Plus strand
chr14:101,514,995-101,515,085
(GRCh37/hg19)
Size:
91 bases
Orientation:
Plus strand

Genomic View for MIR544A Gene

Genes around MIR544A on UCSC Golden Path with GeneCards custom track
MIR544A in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR544A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR544A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR544A Gene

Proteins for MIR544A Gene

Post-translational modifications for MIR544A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR544A Gene

Domains & Families for MIR544A Gene

Gene Families for MIR544A Gene

genes like me logo Genes that share domains with MIR544A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR544A Gene

Function for MIR544A Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR544A Gene

Localization for MIR544A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR544A gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
nucleus 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR544A Gene

Pathways & Interactions for MIR544A Gene

PathCards logo

SuperPathways for MIR544A Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR544A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR544A: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR544A Gene

Drugs & Compounds for MIR544A Gene

No Compound Related Data Available

Transcripts for MIR544A Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR544A Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000674174_9606 precursor_RNA 91 5

HGNC: 32530,

RefSeq: NR_030257,

Ensembl: ENST00000384855 (view in UCSC) ,

miRBase: MI0003515,

Rfam: RF01045,

URS00001934CD_9606 miRNA 22 4

RefSeq: NR_030257,

LncBase: hsa-miR-544a,

miRBase: MIMAT0003164,

TarBase: hsa-miR-544a,

URS0000EFE995_9606 precursor_RNA 58 1

MirGeneDB: Hsa-Mir-544,

URS000075CDE1_9606 miRNA 21 1

MirGeneDB: Hsa-Mir-544_3p,

URS0000EFEE85_9606 miRNA 21 1

MirGeneDB: Hsa-Mir-544_5p,

MIR544A in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR544A Gene

No ASD Table

Relevant External Links for MIR544A Gene

GeneLoc Exon Structure for
MIR544A

No data available for mRNA/cDNA for MIR544A Gene

Expression for MIR544A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR544A Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR544A

genes like me logo Genes that share expression patterns with MIR544A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR544A Gene

Orthologs for MIR544A Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR544A Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-544 31
  • 100 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia bta-mir-544a 31
  • 98 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia cfa-mir-544 31
  • 97 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Mir544 31
  • 95 (a)
OneToOne
Species where no ortholog for MIR544A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR544A Gene

ENSEMBL:
Gene Tree for MIR544A (if available)
TreeFam:
Gene Tree for MIR544A (if available)

Paralogs for MIR544A Gene

No data available for Paralogs for MIR544A Gene

Variants for MIR544A Gene

Additional dbSNP identifiers (rs#s) for MIR544A Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR544A Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR544A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR544A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR544A Gene

Disorders for MIR544A Gene

Additional Disease Information for MIR544A

No disorders were found for MIR544A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR544A Gene

Publications for MIR544A Gene

  1. MicroRNA-544 attenuates diabetic renal injury via suppressing glomerulosclerosis and inflammation by targeting FASN. (PMID: 31323309) Sun T … Ma F (Gene 2020) 3
  2. GKN1 expression in gastric cancer cells is negatively regulated by miR-544a. (PMID: 31509760) Stella di Stadio C … Arcari P (Biochimie 2019) 3
  3. LncRNA GAS5 enhanced the killing effect of NK cell on liver cancer through regulating miR-544/RUNX3. (PMID: 30774011) Fang P … Pan C (Innate immunity 2019) 3
  4. miR-144-5p Enhances the Radiosensitivity of Non-Small-Cell Lung Cancer Cells via Targeting ATF2. (PMID: 29850528) Song L … Li D (BioMed research international 2018) 3
  5. TINCR suppresses proliferation and invasion through regulating miR-544a/FBXW7 axis in lung cancer. (PMID: 29324317) Liu X … Li L (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018) 3

Products for MIR544A Gene

Sources for MIR544A Gene