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Aliases for MIR522 Gene

Subcategory (RNA class) for MIR522 Gene


Quality Score for this RNA gene is


Aliases for MIR522 Gene

  • MicroRNA 522 2 3 5
  • Hsa-Mir-522 3
  • Mir-522 3
  • MIRN522 3

External Ids for MIR522 Gene

ORGUL Members for MIR522 Gene

Previous HGNC Symbols for MIR522 Gene

  • MIRN522

Previous GeneCards Identifiers for MIR522 Gene

  • GC19P058978
  • GC19P059021
  • GC19P054254

Summaries for MIR522 Gene

Entrez Gene Summary for MIR522 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR522 Gene

MIR522 (MicroRNA 522) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR522 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR522 Gene

Genomics for MIR522 Gene

Genomic Locations for MIR522 Gene

Genomic Locations for MIR522 Gene
87 bases
Plus strand

Genomic View for MIR522 Gene

Genes around MIR522 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR522 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR522 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR522 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR522 Gene

Proteins for MIR522 Gene

Post-translational modifications for MIR522 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR522 Gene

Domains & Families for MIR522 Gene

Gene Families for MIR522 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR522: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR522 Gene

Function for MIR522 Gene

Gene Ontology (GO) - Molecular Function for MIR522 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with MIR522: view

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR522 Gene

Localization for MIR522 Gene

Gene Ontology (GO) - Cellular Components for MIR522 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with MIR522: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR522 Gene

Pathways & Interactions for MIR522 Gene

SuperPathways for MIR522 Gene

No Data Available

Interacting Proteins for MIR522 Gene

Gene Ontology (GO) - Biological Process for MIR522 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with MIR522: view

No data available for Pathways by source and SIGNOR curated interactions for MIR522 Gene

Drugs & Compounds for MIR522 Gene

No Compound Related Data Available

Transcripts for MIR522 Gene

mRNA/cDNA for MIR522 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR522 Gene

No ASD Table

Relevant External Links for MIR522 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR522 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR522 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR522 Gene:

genes like me logo Genes that share expression patterns with MIR522: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR522 Gene

Orthologs for MIR522 Gene

Evolution for MIR522 Gene

Gene Tree for MIR522 (if available)
Gene Tree for MIR522 (if available)

No data available for Orthologs for MIR522 Gene

Paralogs for MIR522 Gene

No data available for Paralogs for MIR522 Gene

Variants for MIR522 Gene

Sequence variations from dbSNP and Humsavar for MIR522 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000648907 -- 53,751,443(+) A/G downstream_transcript_variant
rs1001419882 -- 53,749,307(+) C/T upstream_transcript_variant
rs1002738325 -- 53,751,633(+) G/A/T downstream_transcript_variant
rs1003577896 -- 53,749,916(+) T/C upstream_transcript_variant
rs1007323179 -- 53,750,223(+) T/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR522 Gene

Variant ID Type Subtype PubMed ID
esv2448351 CNV deletion 19546169
esv2718812 CNV deletion 23290073
esv2718833 CNV deletion 23290073
nsv458781 CNV gain 19166990
nsv580108 CNV gain 21841781
nsv961246 CNV duplication 23825009

Additional Variant Information for MIR522 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR522 Gene

Disorders for MIR522 Gene

Additional Disease Information for MIR522

No disorders were found for MIR522 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR522 Gene

Publications for MIR522 Gene

  1. Novel involvement of miR-522-3p in high-mobility group box 1-induced prostaglandin reductase 1 expression and reduction of phagocytosis. (PMID: 28088550) Kang GJ … Lee CH (Biochimica et biophysica acta 2017) 3 58
  2. miR-522 contributes to cell proliferation of hepatocellular carcinoma by targeting DKK1 and SFRP2. (PMID: 26960688) Zhang H … Sun C (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 3 58
  3. MiR-522 contributes to cell proliferation of human glioblastoma cells by suppressing PHLPP1 expression. (PMID: 25776496) Zhang S … Liu Y (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015) 3 58
  4. MicroRNA-522 reverses drug resistance of doxorubicin-induced HT29 colon cancer cell by targeting ABCB5. (PMID: 26043974) Yang G … Wu D (Molecular medicine reports 2015) 3 58
  5. Sequencing of captive target transcripts identifies the network of regulated genes and functions of primate-specific miR-522. (PMID: 25131211) Tan SM … Lieberman J (Cell reports 2014) 3 58

Products for MIR522 Gene

Sources for MIR522 Gene

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