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Aliases for MIR519A2 Gene

Subcategory (RNA class) for MIR519A2 Gene


Quality Score for this RNA gene is


Aliases for MIR519A2 Gene

  • MicroRNA 519a-2 2 3 5
  • Hsa-Mir-519a-2 3
  • Mir-519a-2 3
  • MIRN519A-2 3
  • MIRN519A2 3

External Ids for MIR519A2 Gene

ORGUL Members for MIR519A2 Gene

Previous HGNC Symbols for MIR519A2 Gene

  • MIRN519A-2
  • MIRN519A2

Previous GeneCards Identifiers for MIR519A2 Gene

  • GC19P058990
  • GC19P059029
  • GC19P054266
  • GC19P054268
  • GC19P054316
  • GC19P054341
  • GC19P054426
  • GC19P054506
  • GC19P053793
  • GC19P053826

Summaries for MIR519A2 Gene

Entrez Gene Summary for MIR519A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR519A2 Gene

MIR519A2 (MicroRNA 519a-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR519A2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR519A2 Gene

Genomics for MIR519A2 Gene

Genomic Locations for MIR519A2 Gene

Genomic Locations for MIR519A2 Gene
87 bases
Plus strand

Genomic View for MIR519A2 Gene

Genes around MIR519A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR519A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR519A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR519A2 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR519A2 Gene

Proteins for MIR519A2 Gene

Post-translational modifications for MIR519A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR519A2 Gene

Domains & Families for MIR519A2 Gene

Gene Families for MIR519A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR519A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR519A2 Gene

Function for MIR519A2 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR519A2 Gene

Localization for MIR519A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR519A2 Gene

Pathways & Interactions for MIR519A2 Gene

SuperPathways for MIR519A2 Gene

No Data Available

Interacting Proteins for MIR519A2 Gene

Gene Ontology (GO) - Biological Process for MIR519A2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR519A2 Gene

Drugs & Compounds for MIR519A2 Gene

No Compound Related Data Available

Transcripts for MIR519A2 Gene

mRNA/cDNA for MIR519A2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR519A2 Gene

No ASD Table

Relevant External Links for MIR519A2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR519A2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR519A2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR519A2 Gene

This gene is overexpressed in Testis (x40.1) and Breast - Mammary Tissue (x4.6).

NURSA nuclear receptor signaling pathways regulating expression of MIR519A2 Gene:

genes like me logo Genes that share expression patterns with MIR519A2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR519A2 Gene

Orthologs for MIR519A2 Gene

Evolution for MIR519A2 Gene

Gene Tree for MIR519A2 (if available)
Gene Tree for MIR519A2 (if available)

No data available for Orthologs for MIR519A2 Gene

Paralogs for MIR519A2 Gene

No data available for Paralogs for MIR519A2 Gene

Variants for MIR519A2 Gene

Sequence variations from dbSNP and Humsavar for MIR519A2 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000962107 -- 53,760,731(+) A/G upstream_transcript_variant
rs1002008394 -- 53,761,858(+) C/T upstream_transcript_variant
rs1002508335 -- 53,760,783(+) A/T upstream_transcript_variant
rs1004814821 -- 53,760,447(+) C/T upstream_transcript_variant
rs1005517202 -- 53,762,692(+) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR519A2 Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV deletion 23290073
nsv1058969 CNV gain 25217958
nsv458781 CNV gain 19166990
nsv580108 CNV gain 21841781
nsv961246 CNV duplication 23825009

Additional Variant Information for MIR519A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR519A2 Gene

Disorders for MIR519A2 Gene

Additional Disease Information for MIR519A2

No disorders were found for MIR519A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR519A2 Gene

Publications for MIR519A2 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours. (PMID: 21083603) Kim TH … An HJ (Histopathology 2010) 3 58
  3. miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels. (PMID: 19088191) Abdelmohsen K … Gorospe M (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 58
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR519A2 Gene

Sources for MIR519A2 Gene

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