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Aliases for MIR5195 Gene

Subcategory (RNA class) for MIR5195 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5195 Gene

  • MicroRNA 5195 2 3 5
  • Hsa-Mir-5195 3

External Ids for MIR5195 Gene

Previous GeneCards Identifiers for MIR5195 Gene

  • GC14U901322
  • GC14M106888
  • GC14M107543
  • GC14M107803
  • GC14M107896
  • GC14M107995
  • GC14M108116
  • GC14M108257

Summaries for MIR5195 Gene

Entrez Gene Summary for MIR5195 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5195 Gene

MIR5195 (MicroRNA 5195) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5195 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5195 Gene

Genomics for MIR5195 Gene

GeneHancer (GH) Regulatory Elements for MIR5195 Gene

Promoters and enhancers for MIR5195 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I106850 Enhancer 0.8 ENCODE dbSUPER 550.8 -0.3 -309 1.3 RXRA EBF1 REST POLR2A IKZF1 ZSCAN29 RUNX3 IKZF2 IGHV5-78 MIR5195 IGH
GH14I106848 Enhancer 0.9 Ensembl ENCODE 0.8 +2.3 2266 1.1 CTCF PKNOX1 TFAP4 SAP130 SIN3A FEZF1 ZIC2 RAD21 ZSCAN5C ZNF143 MIR5195 IGHVIII-76-1 IGH
GH14I106843 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +5.5 5471 4.3 HDGF PKNOX1 ATF1 FOXA2 SMAD1 ARID4B FEZF1 DMAP1 ZNF48 GLIS2 IGHV2-70D MIR5195 IGHVIII-76-1 IGH
GH14I106842 Enhancer 0.5 ENCODE 0.4 +8.2 8239 0.2 ELF3 CTCF TEAD1 ZNF444 RAD21 MIXL1 TEAD3 MIR5195 IGHVIII-76-1 IGH
GH14I106840 Enhancer 0.3 ENCODE 0.4 +10.5 10539 0.2 CTCF IGHVIII-76-1 MIR5195 IGH
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5195 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5195 Gene

Genomic Locations for MIR5195 Gene
chr14:106,850,885-106,850,999
(GRCh38/hg38)
Size:
115 bases
Orientation:
Minus strand

Genomic View for MIR5195 Gene

Genes around MIR5195 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5195 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5195 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5195 Gene

Proteins for MIR5195 Gene

Post-translational modifications for MIR5195 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5195 Gene

Domains & Families for MIR5195 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5195 Gene

Function for MIR5195 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5195 Gene

Localization for MIR5195 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5195 Gene

Pathways & Interactions for MIR5195 Gene

SuperPathways for MIR5195 Gene

No Data Available

Interacting Proteins for MIR5195 Gene

Gene Ontology (GO) - Biological Process for MIR5195 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5195 Gene

Drugs & Compounds for MIR5195 Gene

No Compound Related Data Available

Transcripts for MIR5195 Gene

mRNA/cDNA for MIR5195 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5195 Gene

No ASD Table

Relevant External Links for MIR5195 Gene

GeneLoc Exon Structure for
MIR5195
ECgene alternative splicing isoforms for
MIR5195

Expression for MIR5195 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5195 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5195 Gene:

MIR5195
genes like me logo Genes that share expression patterns with MIR5195: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5195 Gene

Orthologs for MIR5195 Gene

Evolution for MIR5195 Gene

ENSEMBL:
Gene Tree for MIR5195 (if available)
TreeFam:
Gene Tree for MIR5195 (if available)

No data available for Orthologs for MIR5195 Gene

Paralogs for MIR5195 Gene

No data available for Paralogs for MIR5195 Gene

Variants for MIR5195 Gene

Sequence variations from dbSNP and Humsavar for MIR5195 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000321161 -- 106,852,545(-) A/T upstream_transcript_variant
rs1001500111 -- 106,852,768(-) A/G upstream_transcript_variant
rs1002182993 -- 106,852,062(-) G/A upstream_transcript_variant
rs1002906370 -- 106,851,592(-) G/A upstream_transcript_variant
rs1003465901 -- 106,850,510(-) A/C/G downstream_transcript_variant

Additional Variant Information for MIR5195 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5195

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5195 Gene

Disorders for MIR5195 Gene

Additional Disease Information for MIR5195

No disorders were found for MIR5195 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5195 Gene

Publications for MIR5195 Gene

  1. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  3. miR-5195-3p Inhibits Proliferation and Invasion of Human Bladder Cancer Cells by Directly Targeting Oncogene KLF5. (PMID: 28109084) Jiang Z … Xiao J (Oncology research 2017) 3

Products for MIR5195 Gene

Sources for MIR5195 Gene

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