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Aliases for MIR5193 Gene

Subcategory (RNA class) for MIR5193 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5193 Gene

  • MicroRNA 5193 2 3 5
  • Hsa-Mir-5193 3
  • Mir-5193 3

External Ids for MIR5193 Gene

Previous GeneCards Identifiers for MIR5193 Gene

  • GC03U901841
  • GC03M049847
  • GC03M049849

Summaries for MIR5193 Gene

Entrez Gene Summary for MIR5193 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5193 Gene

MIR5193 (MicroRNA 5193) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Cytokine Signaling in Immune system and Transport of the SLBP independent Mature mRNA.

Additional gene information for MIR5193 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5193 Gene

Genomics for MIR5193 Gene

GeneHancer (GH) Regulatory Elements for MIR5193 Gene

Promoters and enhancers for MIR5193 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I049802 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 550.8 +0.5 467 7.2 HDGF CLOCK ARID4B SIN3A YBX1 DMAP1 ZNF2 ZNF766 ZNF207 ZNF143 FAM212A MIR5193 CDHR4 AMT WDR6 UBA7 GC03P049762 GC03P049763 GC03P049421
GH03I049812 Promoter/Enhancer 2 EPDnew Ensembl ENCODE dbSUPER 0.4 -7.7 -7710 2.5 ELF3 FOXA2 ARID4B RAD21 ETS1 ZNF766 IKZF2 THAP11 HCFC1 RXRA UBA7 CDHR4 MIR5193 GC03P049763 GC03P049762 GC03P049421
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5193 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5193 Gene

Genomic Locations for MIR5193 Gene
chr3:49,806,137-49,806,245
(GRCh38/hg38)
Size:
109 bases
Orientation:
Minus strand
chr3:49,843,570-49,843,678
(GRCh37/hg19)

Genomic View for MIR5193 Gene

Genes around MIR5193 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5193 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5193 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5193 Gene

Proteins for MIR5193 Gene

Post-translational modifications for MIR5193 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5193 Gene

Domains & Families for MIR5193 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5193 Gene

Function for MIR5193 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5193 Gene

Localization for MIR5193 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5193 Gene

Pathways & Interactions for MIR5193 Gene

genes like me logo Genes that share pathways with MIR5193: view

Interacting Proteins for MIR5193 Gene

Gene Ontology (GO) - Biological Process for MIR5193 Gene

None

No data available for SIGNOR curated interactions for MIR5193 Gene

Drugs & Compounds for MIR5193 Gene

No Compound Related Data Available

Transcripts for MIR5193 Gene

mRNA/cDNA for MIR5193 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5193 Gene

No ASD Table

Relevant External Links for MIR5193 Gene

GeneLoc Exon Structure for
MIR5193
ECgene alternative splicing isoforms for
MIR5193

Expression for MIR5193 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5193 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5193 Gene:

MIR5193
genes like me logo Genes that share expression patterns with MIR5193: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5193 Gene

Orthologs for MIR5193 Gene

Evolution for MIR5193 Gene

ENSEMBL:
Gene Tree for MIR5193 (if available)
TreeFam:
Gene Tree for MIR5193 (if available)

No data available for Orthologs for MIR5193 Gene

Paralogs for MIR5193 Gene

No data available for Paralogs for MIR5193 Gene

Variants for MIR5193 Gene

Sequence variations from dbSNP and Humsavar for MIR5193 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000827279 -- 49,808,231(-) C/T upstream_transcript_variant
rs1003079643 -- 49,806,381(-) A/G upstream_transcript_variant
rs1005032107 -- 49,808,209(-) G/A upstream_transcript_variant
rs1007637878 -- 49,805,817(-) G/A downstream_transcript_variant
rs1008278625 -- 49,807,829(-) C/A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5193 Gene

Variant ID Type Subtype PubMed ID
nsv834688 CNV loss 17160897

Additional Variant Information for MIR5193 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5193

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5193 Gene

Disorders for MIR5193 Gene

Additional Disease Information for MIR5193

No disorders were found for MIR5193 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5193 Gene

Publications for MIR5193 Gene

  1. Human miR-5193 Triggers Gene Silencing in Multiple Genotypes of Hepatitis B Virus. (PMID: 26456535) Khlaiphuengsin A … Payungporn S (MicroRNA (Shariqah, United Arab Emirates) 2015) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5193 Gene

Sources for MIR5193 Gene

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