microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5192 Gene

Subcategory (RNA class) for MIR5192 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR5192 Gene

  • MicroRNA 5192 2 3 5
  • Hsa-Mir-5192 3
  • MIMAT0021123 51
  • MI0018171 51
  • MIR5192 2

External Ids for MIR5192 Gene

Previous GeneCards Identifiers for MIR5192 Gene

  • GC02U902488
  • GC02P062434

Summaries for MIR5192 Gene

Entrez Gene Summary for MIR5192 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5192 Gene

MIR5192 (MicroRNA 5192) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5192 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5192 Gene

Genomics for MIR5192 Gene

GeneHancer (GH) Regulatory Elements for MIR5192 Gene

Promoters and enhancers for MIR5192 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J062194 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -8.2 -8217 7.2 FOXK2 HNRNPK ZBTB40 SIN3A POLR2G NCOR1 GTF2E2 PHF8 ZFX ZIC2 B3GNT2 XPO1 MIR5192 lnc-CCT4-2
GH02J062202 Enhancer 0.8 ENCODE 0.7 -3.1 -3093 0.5 ZIC2 RUNX1 CTBP1 MYC TRIM22 TRIM25 KDM4B BCL11A NCOR1 CEBPB MIR5192 B3GNT2 lnc-CCT4-2
GH02J062208 Enhancer 0.7 ENCODE 0.7 +3.2 3224 1.3 ZIC2 NFIC MYNN MEF2B ZFHX2 EBF1 HDAC2 NFIB VEZF1 GLIS1 MIR5192 B3GNT2 piR-50443-213 lnc-CCT4-2
GH02J062214 Promoter/Enhancer 1.1 EPDnew ENCODE 0.4 +10.4 10369 2.6 FOS ZNF341 NR2F2 CEBPB GATA3 POLR2A MBD1 RBBP5 RBM22 JUND B3GNT2 MIR5192 piR-50443-213 lnc-CCT4-2
GH02J062209 Enhancer 0.3 ENCODE 0.7 +4.0 4011 0 POLR2A SCRT2 MIR5192 B3GNT2 piR-50443-213 lnc-CCT4-2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5192 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5192 Gene

Genomic Locations for MIR5192 Gene
chr2:62,205,826-62,205,917
(GRCh38/hg38)
Size:
92 bases
Orientation:
Plus strand
chr2:62,432,961-62,433,052
(GRCh37/hg19)
Size:
92 bases
Orientation:
Plus strand

Genomic View for MIR5192 Gene

Genes around MIR5192 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5192 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5192 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5192 Gene

Proteins for MIR5192 Gene

Post-translational modifications for MIR5192 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5192 Gene

Domains & Families for MIR5192 Gene

Gene Families for MIR5192 Gene

HGNC:
genes like me logo Genes that share domains with MIR5192: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5192 Gene

Function for MIR5192 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5192 Gene

Localization for MIR5192 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5192 Gene

Pathways & Interactions for MIR5192 Gene

PathCards logo

SuperPathways for MIR5192 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR5192 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR5192 Gene

Drugs & Compounds for MIR5192 Gene

No Compound Related Data Available

Transcripts for MIR5192 Gene

mRNA/cDNA for MIR5192 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5192 Gene

No ASD Table

Relevant External Links for MIR5192 Gene

GeneLoc Exon Structure for
MIR5192

Expression for MIR5192 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR5192 Gene

genes like me logo Genes that share expression patterns with MIR5192: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5192 Gene

Orthologs for MIR5192 Gene

Evolution for MIR5192 Gene

ENSEMBL:
Gene Tree for MIR5192 (if available)
TreeFam:
Gene Tree for MIR5192 (if available)

No data available for Orthologs for MIR5192 Gene

Paralogs for MIR5192 Gene

No data available for Paralogs for MIR5192 Gene

Variants for MIR5192 Gene

Additional dbSNP identifiers (rs#s) for MIR5192 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR5192 Gene

Variant ID Type Subtype PubMed ID
nsv1000005 CNV gain 25217958
nsv582123 CNV gain 21841781
nsv7313 OTHER inversion 18451855

Additional Variant Information for MIR5192 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5192

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5192 Gene

Disorders for MIR5192 Gene

Additional Disease Information for MIR5192

No disorders were found for MIR5192 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5192 Gene

Publications for MIR5192 Gene

  1. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR5192 Gene

Sources for MIR5192 Gene