microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5191 Gene

Subcategory (RNA class) for MIR5191 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR5191 Gene

  • MicroRNA 5191 2 3 5
  • Hsa-Mir-5191 3
  • MIMAT0021122 53
  • MI0018170 53
  • MIR5191 2

External Ids for MIR5191 Gene

Previous GeneCards Identifiers for MIR5191 Gene

  • GC01U903364

Summaries for MIR5191 Gene

Entrez Gene Summary for MIR5191 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5191 Gene

MIR5191 (MicroRNA 5191) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5191 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5191 Gene

Genomics for MIR5191 Gene

GeneHancer (GH) Regulatory Elements for MIR5191 Gene

Promoters and enhancers for MIR5191 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5191 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5191 Gene

Genomic Locations for MIR5191 Gene
chr1:201,719,508-201,719,627
(GRCh38/hg38)
Size:
120 bases
Orientation:
Plus strand
chr1:201,688,636-201,688,755
(GRCh37/hg19)
Size:
120 bases
Orientation:
Plus strand

Genomic View for MIR5191 Gene

Genes around MIR5191 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5191 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5191 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5191 Gene

Proteins for MIR5191 Gene

Post-translational modifications for MIR5191 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5191 Gene

Domains & Families for MIR5191 Gene

Gene Families for MIR5191 Gene

HGNC:
genes like me logo Genes that share domains with MIR5191: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5191 Gene

Function for MIR5191 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5191 Gene

Localization for MIR5191 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5191 Gene

Pathways & Interactions for MIR5191 Gene

PathCards logo

SuperPathways for MIR5191 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR5191 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5191 Gene

Drugs & Compounds for MIR5191 Gene

No Compound Related Data Available

Transcripts for MIR5191 Gene

mRNA/cDNA for MIR5191 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5191 Gene

No ASD Table

Relevant External Links for MIR5191 Gene

GeneLoc Exon Structure for
MIR5191
ECgene alternative splicing isoforms for
MIR5191

Expression for MIR5191 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5191 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5191 Gene:

MIR5191
genes like me logo Genes that share expression patterns with MIR5191: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5191 Gene

Orthologs for MIR5191 Gene

Evolution for MIR5191 Gene

ENSEMBL:
Gene Tree for MIR5191 (if available)
TreeFam:
Gene Tree for MIR5191 (if available)

No data available for Orthologs for MIR5191 Gene

Paralogs for MIR5191 Gene

No data available for Paralogs for MIR5191 Gene

Variants for MIR5191 Gene

Sequence variations from dbSNP and Humsavar for MIR5191 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000034943 -- 201,719,525(+) A/C non_coding_transcript_variant
rs1000487203 -- 201,717,604(+) C/T upstream_transcript_variant
rs1001253028 -- 201,719,105(+) C/G upstream_transcript_variant
rs1003038303 -- 201,719,363(+) C/T upstream_transcript_variant
rs1004766008 -- 201,718,016(+) A/C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5191 Gene

Variant ID Type Subtype PubMed ID
dgv136e212 CNV loss 25503493

Additional Variant Information for MIR5191 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5191

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5191 Gene

Disorders for MIR5191 Gene

Additional Disease Information for MIR5191

No disorders were found for MIR5191 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5191 Gene

Publications for MIR5191 Gene

  1. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR5191 Gene

Sources for MIR5191 Gene