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Aliases for MIR518C Gene

Subcategory (RNA class) for MIR518C Gene


Quality Score for this RNA gene is


Aliases for MIR518C Gene

  • MicroRNA 518c 2 3 5
  • Hsa-Mir-518c 3
  • MIRN518C 3
  • MiR-518 3

External Ids for MIR518C Gene

ORGUL Members for MIR518C Gene

Previous HGNC Symbols for MIR518C Gene

  • MIRN518C

Previous GeneCards Identifiers for MIR518C Gene

  • GC19P058938
  • GC19P059002
  • GC19P054212
  • GC19P054218
  • GC19P054258
  • GC19P054313
  • GC19P054335
  • GC19P054406
  • GC19P054483
  • GC19P053709
  • GC19P053738
  • GC19P053776
  • GC19P053812
  • GC19P053815
  • GC19P053824
  • GC19P053845

Summaries for MIR518C Gene

Entrez Gene Summary for MIR518C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR518C Gene

MIR518C (MicroRNA 518c) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR518C Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR518C Gene

Genomics for MIR518C Gene

Genomic Locations for MIR518C Gene

Genomic Locations for MIR518C Gene
101 bases
Plus strand

Genomic View for MIR518C Gene

Genes around MIR518C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR518C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR518C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR518C Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR518C Gene

Proteins for MIR518C Gene

Post-translational modifications for MIR518C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR518C Gene

Domains & Families for MIR518C Gene

Gene Families for MIR518C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR518C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR518C Gene

Function for MIR518C Gene

Gene Ontology (GO) - Molecular Function for MIR518C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 22203747
genes like me logo Genes that share ontologies with MIR518C: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR518C Gene

Localization for MIR518C Gene

Gene Ontology (GO) - Cellular Components for MIR518C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with MIR518C: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR518C Gene

Pathways & Interactions for MIR518C Gene

SuperPathways for MIR518C Gene

No Data Available

Interacting Proteins for MIR518C Gene

Gene Ontology (GO) - Biological Process for MIR518C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
GO:0035195 gene silencing by miRNA IDA 22203747
genes like me logo Genes that share ontologies with MIR518C: view

No data available for Pathways by source and SIGNOR curated interactions for MIR518C Gene

Drugs & Compounds for MIR518C Gene

No Compound Related Data Available

Transcripts for MIR518C Gene

mRNA/cDNA for MIR518C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR518C Gene

No ASD Table

Relevant External Links for MIR518C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR518C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR518C Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR518C Gene:

genes like me logo Genes that share expression patterns with MIR518C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR518C Gene

Orthologs for MIR518C Gene

Evolution for MIR518C Gene

Gene Tree for MIR518C (if available)
Gene Tree for MIR518C (if available)

No data available for Orthologs for MIR518C Gene

Paralogs for MIR518C Gene

No data available for Paralogs for MIR518C Gene

Variants for MIR518C Gene

Sequence variations from dbSNP and Humsavar for MIR518C Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000321090 -- 53,709,186(+) C/T downstream_transcript_variant
rs1000385722 -- 53,707,154(+) A/G upstream_transcript_variant
rs1002282558 -- 53,708,118(+) G/C upstream_transcript_variant
rs1003283956 -- 53,709,239(+) G/C downstream_transcript_variant
rs1003664802 -- 53,706,803(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR518C Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV deletion 23290073
esv2718833 CNV deletion 23290073
esv2718836 CNV deletion 23290073
esv2762049 CNV gain 21179565
nsv458781 CNV gain 19166990
nsv580107 CNV gain 21841781
nsv580108 CNV gain 21841781
nsv961246 CNV duplication 23825009

Additional Variant Information for MIR518C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR518C Gene

Disorders for MIR518C Gene

Additional Disease Information for MIR518C

No disorders were found for MIR518C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR518C Gene

Publications for MIR518C Gene

  1. MicroRNA Species in Follicular Fluid Associating With Polycystic Ovary Syndrome and Related Intermediary Phenotypes. (PMID: 26771704) Sørensen AE … Dalgaard LT (The Journal of clinical endocrinology and metabolism 2016) 3 58
  2. Common variants in TGFBR2 and miR-518 genes are associated with hypertension in the Chinese population. (PMID: 24687999) Chen J … Yang S (American journal of hypertension 2014) 3 58
  3. Hydroxysteroid (17-β) dehydrogenase 1 is dysregulated by miR-210 and miR-518c that are aberrantly expressed in preeclamptic placentas: a novel marker for predicting preeclampsia. (PMID: 22203747) Ishibashi O … Takizawa T (Hypertension (Dallas, Tex. : 1979) 2012) 3 58
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR518C Gene

Sources for MIR518C Gene

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