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Aliases for MIR5188 Gene

Subcategory (RNA class) for MIR5188 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5188 Gene

  • MicroRNA 5188 2 3 5
  • Hsa-Mir-5188 3
  • Mir-5188 3

External Ids for MIR5188 Gene

Previous GeneCards Identifiers for MIR5188 Gene

  • GC12U901639
  • GC12P125402
  • GC12P125404

Summaries for MIR5188 Gene

Entrez Gene Summary for MIR5188 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5188 Gene

MIR5188 (MicroRNA 5188) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5188 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5188 Gene

Genomics for MIR5188 Gene

GeneHancer (GH) Regulatory Elements for MIR5188 Gene

Promoters and enhancers for MIR5188 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I124913 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.8 +3.6 3636 12.7 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF416 UBC NCOR2 DHX37 ENSG00000270130 ENSG00000269938 ENSG00000269997 ENSG00000270061 DNAH10OS SCARB1 BRI3BP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5188 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5188 Gene

Genomic Locations for MIR5188 Gene
chr12:124,915,547-124,915,659
(GRCh38/hg38)
Size:
113 bases
Orientation:
Plus strand
chr12:125,400,093-125,400,205
(GRCh37/hg19)

Genomic View for MIR5188 Gene

Genes around MIR5188 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5188 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5188 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5188 Gene

Proteins for MIR5188 Gene

Post-translational modifications for MIR5188 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5188 Gene

Domains & Families for MIR5188 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5188 Gene

Function for MIR5188 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5188 Gene

Localization for MIR5188 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5188 Gene

Pathways & Interactions for MIR5188 Gene

SuperPathways for MIR5188 Gene

No Data Available

Interacting Proteins for MIR5188 Gene

Gene Ontology (GO) - Biological Process for MIR5188 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5188 Gene

Drugs & Compounds for MIR5188 Gene

No Compound Related Data Available

Transcripts for MIR5188 Gene

mRNA/cDNA for MIR5188 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5188 Gene

No ASD Table

Relevant External Links for MIR5188 Gene

GeneLoc Exon Structure for
MIR5188
ECgene alternative splicing isoforms for
MIR5188

Expression for MIR5188 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5188 Gene

mRNA differential expression in normal tissues according to GTEx for MIR5188 Gene

This gene is overexpressed in Testis (x46.7) and Esophagus - Mucosa (x6.3).

NURSA nuclear receptor signaling pathways regulating expression of MIR5188 Gene:

MIR5188
genes like me logo Genes that share expression patterns with MIR5188: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5188 Gene

Orthologs for MIR5188 Gene

Evolution for MIR5188 Gene

ENSEMBL:
Gene Tree for MIR5188 (if available)
TreeFam:
Gene Tree for MIR5188 (if available)

No data available for Orthologs for MIR5188 Gene

Paralogs for MIR5188 Gene

No data available for Paralogs for MIR5188 Gene

Variants for MIR5188 Gene

Sequence variations from dbSNP and Humsavar for MIR5188 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1000263784 -- 124,916,004(+) C/G/T downstream_transcript_variant
rs1000340405 -- 124,915,676(+) G/A downstream_transcript_variant
rs1001268579 -- 124,915,001(+) G/C upstream_transcript_variant
rs1002329979 -- 124,914,412(+) A/G upstream_transcript_variant
rs1002551196 -- 124,913,855(+) G/A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5188 Gene

Variant ID Type Subtype PubMed ID
nsv560595 CNV gain 21841781

Additional Variant Information for MIR5188 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5188

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5188 Gene

Disorders for MIR5188 Gene

Additional Disease Information for MIR5188

No disorders were found for MIR5188 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5188 Gene

Publications for MIR5188 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5188 Gene

Sources for MIR5188 Gene

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