microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5093 Gene

Subcategory (RNA class) for MIR5093 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR5093 Gene

  • MicroRNA 5093 2 3 5
  • Hsa-Mir-5093 3
  • MIMAT0021085 53
  • MI0017982 53
  • MIR5093 2

External Ids for MIR5093 Gene

Previous GeneCards Identifiers for MIR5093 Gene

  • GC16U901380
  • GC16M085342

Summaries for MIR5093 Gene

Entrez Gene Summary for MIR5093 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5093 Gene

MIR5093 (MicroRNA 5093) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5093 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5093 Gene

Genomics for MIR5093 Gene

GeneHancer (GH) Regulatory Elements for MIR5093 Gene

Promoters and enhancers for MIR5093 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5093 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5093 Gene

Genomic Locations for MIR5093 Gene
chr16:85,306,226-85,306,325
(GRCh38/hg38)
Size:
100 bases
Orientation:
Minus strand
chr16:85,339,832-85,339,931
(GRCh37/hg19)
Size:
100 bases
Orientation:
Minus strand

Genomic View for MIR5093 Gene

Genes around MIR5093 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5093 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5093 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5093 Gene

Proteins for MIR5093 Gene

Post-translational modifications for MIR5093 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5093 Gene

Domains & Families for MIR5093 Gene

Gene Families for MIR5093 Gene

HGNC:
genes like me logo Genes that share domains with MIR5093: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5093 Gene

Function for MIR5093 Gene

Phenotypes From GWAS Catalog for MIR5093 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5093 Gene

Localization for MIR5093 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5093 Gene

Pathways & Interactions for MIR5093 Gene

PathCards logo

SuperPathways for MIR5093 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR5093 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5093 Gene

Drugs & Compounds for MIR5093 Gene

No Compound Related Data Available

Transcripts for MIR5093 Gene

mRNA/cDNA for MIR5093 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5093 Gene

No ASD Table

Relevant External Links for MIR5093 Gene

GeneLoc Exon Structure for
MIR5093
ECgene alternative splicing isoforms for
MIR5093

Expression for MIR5093 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5093 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5093 Gene:

MIR5093
genes like me logo Genes that share expression patterns with MIR5093: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5093 Gene

Orthologs for MIR5093 Gene

Evolution for MIR5093 Gene

ENSEMBL:
Gene Tree for MIR5093 (if available)
TreeFam:
Gene Tree for MIR5093 (if available)

No data available for Orthologs for MIR5093 Gene

Paralogs for MIR5093 Gene

No data available for Paralogs for MIR5093 Gene

Variants for MIR5093 Gene

Sequence variations from dbSNP and Humsavar for MIR5093 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000016207 -- 85,307,769(-) A/C/G upstream_transcript_variant
rs1000124543 -- 85,308,213(-) C/T upstream_transcript_variant
rs1000162898 -- 85,306,088(-) C/G downstream_transcript_variant
rs1000610415 -- 85,306,867(-) G/A upstream_transcript_variant
rs1000681791 -- 85,305,852(-) A/C/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5093 Gene

Variant ID Type Subtype PubMed ID
nsv483044 CNV gain 15286789
nsv833312 CNV loss 17160897
nsv833313 CNV loss 17160897
nsv952062 CNV deletion 24416366

Additional Variant Information for MIR5093 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5093

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5093 Gene

Disorders for MIR5093 Gene

Additional Disease Information for MIR5093

No disorders were found for MIR5093 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5093 Gene

Publications for MIR5093 Gene

  1. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N … Zhou G (Journal of radiation research 2011) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR5093 Gene

Sources for MIR5093 Gene