microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5047 Gene

Subcategory (RNA class) for MIR5047 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR5047 Gene

  • MicroRNA 5047 2 3 5
  • Hsa-Mir-5047 3
  • MIMAT0020541 53
  • MI0017932 53
  • MIR5047 2

External Ids for MIR5047 Gene

Previous GeneCards Identifiers for MIR5047 Gene

  • GC17U901654
  • GC17M062501

Summaries for MIR5047 Gene

Entrez Gene Summary for MIR5047 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5047 Gene

MIR5047 (MicroRNA 5047) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway.

Additional gene information for MIR5047 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5047 Gene

Genomics for MIR5047 Gene

GeneHancer (GH) Regulatory Elements for MIR5047 Gene

Promoters and enhancers for MIR5047 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J064499 Enhancer 0.5 ENCODE 750.6 +1.3 1305 0.2 POLR2A PRDM10 BACH1 BMI1 CHD1 MIR3064 MIR5047 POLG2 DDX5
GH17J064501 Enhancer 0.3 ENCODE 750.6 +0.7 725 0.2 POLR2A SMAD5 MIR3064 MIR5047 LRRC37A3 POLG2 DDX5
GH17J064500 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.6 -3.7 -3749 8.3 PPP1R10 E2F8 SIN3A ZNF24 ZBTB40 SP1 CTCF ZBTB6 RBPJ SMARCE1 POLG2 CEP95 DDX5 lnc-POLG2-1 FTSJ3 SLC16A6P1 ENSG00000265982 SMARCD2 PLEKHM1P1 DDX42
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5047 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5047 Gene

Genomic Locations for MIR5047 Gene
chr17:64,501,214-64,501,313
(GRCh38/hg38)
Size:
100 bases
Orientation:
Minus strand
chr17:62,497,332-62,497,431
(GRCh37/hg19)
Size:
100 bases
Orientation:
Minus strand

Genomic View for MIR5047 Gene

Genes around MIR5047 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5047 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5047 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5047 Gene

Proteins for MIR5047 Gene

Post-translational modifications for MIR5047 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5047 Gene

Domains & Families for MIR5047 Gene

Gene Families for MIR5047 Gene

HGNC:
genes like me logo Genes that share domains with MIR5047: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5047 Gene

Function for MIR5047 Gene

Phenotypes From GWAS Catalog for MIR5047 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5047 Gene

Localization for MIR5047 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5047 Gene

Pathways & Interactions for MIR5047 Gene

genes like me logo Genes that share pathways with MIR5047: view

Pathways by source for MIR5047 Gene

Gene Ontology (GO) - Biological Process for MIR5047 Gene

None

No data available for SIGNOR curated interactions for MIR5047 Gene

Drugs & Compounds for MIR5047 Gene

No Compound Related Data Available

Transcripts for MIR5047 Gene

mRNA/cDNA for MIR5047 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5047 Gene

No ASD Table

Relevant External Links for MIR5047 Gene

GeneLoc Exon Structure for
MIR5047
ECgene alternative splicing isoforms for
MIR5047

Expression for MIR5047 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5047 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5047 Gene:

MIR5047
genes like me logo Genes that share expression patterns with MIR5047: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5047 Gene

Orthologs for MIR5047 Gene

Evolution for MIR5047 Gene

ENSEMBL:
Gene Tree for MIR5047 (if available)
TreeFam:
Gene Tree for MIR5047 (if available)

No data available for Orthologs for MIR5047 Gene

Paralogs for MIR5047 Gene

No data available for Paralogs for MIR5047 Gene

Variants for MIR5047 Gene

Sequence variations from dbSNP and Humsavar for MIR5047 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1002450072 -- 64,502,274(-) C/T upstream_transcript_variant
rs1017934320 -- 64,500,972(-) T/G downstream_transcript_variant
rs1026440541 -- 64,502,647(-) T/C upstream_transcript_variant
rs1026829610 -- 64,502,336(-) A/G upstream_transcript_variant
rs1031043930 -- 64,501,551(-) A/C upstream_transcript_variant

Additional Variant Information for MIR5047 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5047

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5047 Gene

Disorders for MIR5047 Gene

Additional Disease Information for MIR5047

No disorders were found for MIR5047 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5047 Gene

Publications for MIR5047 Gene

  1. An evolutionarily conserved, alternatively spliced, intron in the p68/DDX5 DEAD-box RNA helicase gene encodes a novel miRNA. (PMID: 21346006) Moore HC … Fuller-Pace FV (RNA (New York, N.Y.) 2011) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR5047 Gene

Sources for MIR5047 Gene