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Aliases for MIR5010 Gene

Subcategory (RNA class) for MIR5010 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5010 Gene

  • MicroRNA 5010 2 3 5
  • Hsa-Mir-5010 3
  • Mir-5010 3

External Ids for MIR5010 Gene

Previous GeneCards Identifiers for MIR5010 Gene

  • GC17U901670
  • GC17P040671
  • GC17P042459

Summaries for MIR5010 Gene

Entrez Gene Summary for MIR5010 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5010 Gene

MIR5010 (MicroRNA 5010) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Innate Immune System and Insulin receptor recycling.

Additional gene information for MIR5010 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5010 Gene

Genomics for MIR5010 Gene

GeneHancer (GH) Regulatory Elements for MIR5010 Gene

Promoters and enhancers for MIR5010 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I042511 Enhancer 1 Ensembl ENCODE dbSUPER 550.8 -0.8 -781 3.6 KLF1 CBFB NR2F1 EBF1 REST NR2F2 RELA POLR2A IKZF1 ZNF143 MIR5010 RNU7-97P ATP6V0A1 CAVIN1 STAT5B KCNH4 HCRT MLX ENSG00000267632
GH17I042308 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 5.2 -198.1 -198132 15.9 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 ZNF263 MEF2D GC17M042314 HMGN1P29 STAT5A ENSG00000267758 ACLY NBR2 ENSG00000267340 PLEKHH3 STAT5B ATP6V0A1
GH17I042328 Enhancer 1 Ensembl ENCODE dbSUPER 4.7 -184.9 -184931 2.4 USF1 MAX SIN3A REST SP1 POLR2A ATF3 POU5F1 ZBTB33 PRDM10 CAVIN1 STAT5B RNU7-97P ATP6V0A1 ZNF385C STAT3 LOC105371781 MIR5010 GC17M042314 GC17M042386
GH17I042324 Enhancer 0.9 ENCODE dbSUPER 4.8 -188.5 -188522 2 FOXA2 JUN MAX SIN3A GATA3 POLR2A FOSL2 FOS CEBPB REST CAVIN1 STAT5B ATP6V0A1 RNU7-97P ZNF385C MIR5010 GC17M042314 STAT3 GC17M042386
GH17I042305 Enhancer 0.7 ENCODE dbSUPER 4.5 -208.0 -207999 1.1 SMAD5 POLR2A SUPT5H ZBTB17 STAT5B ENSG00000236194 ATP6V0A1 MIR5010 PIR49037 GC17M042314 STAT5A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5010 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5010 Gene

Genomic Locations for MIR5010 Gene
chr17:42,514,188-42,514,307
(GRCh38/hg38)
Size:
120 bases
Orientation:
Plus strand
chr17:40,666,206-40,666,325
(GRCh37/hg19)

Genomic View for MIR5010 Gene

Genes around MIR5010 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5010 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5010 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5010 Gene

Proteins for MIR5010 Gene

Post-translational modifications for MIR5010 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5010 Gene

Domains & Families for MIR5010 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5010 Gene

Function for MIR5010 Gene

Phenotypes From GWAS Catalog for MIR5010 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5010 Gene

Localization for MIR5010 Gene

Gene Ontology (GO) - Cellular Components for MIR5010 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR5010: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR5010 Gene

Pathways & Interactions for MIR5010 Gene

genes like me logo Genes that share pathways with MIR5010: view

Pathways by source for MIR5010 Gene

Interacting Proteins for MIR5010 Gene

Gene Ontology (GO) - Biological Process for MIR5010 Gene

None

No data available for SIGNOR curated interactions for MIR5010 Gene

Drugs & Compounds for MIR5010 Gene

No Compound Related Data Available

Transcripts for MIR5010 Gene

mRNA/cDNA for MIR5010 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5010 Gene

No ASD Table

Relevant External Links for MIR5010 Gene

GeneLoc Exon Structure for
MIR5010
ECgene alternative splicing isoforms for
MIR5010

Expression for MIR5010 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5010 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5010 Gene:

MIR5010
genes like me logo Genes that share expression patterns with MIR5010: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5010 Gene

Orthologs for MIR5010 Gene

Evolution for MIR5010 Gene

ENSEMBL:
Gene Tree for MIR5010 (if available)
TreeFam:
Gene Tree for MIR5010 (if available)

No data available for Orthologs for MIR5010 Gene

Paralogs for MIR5010 Gene

No data available for Paralogs for MIR5010 Gene

Variants for MIR5010 Gene

Sequence variations from dbSNP and Humsavar for MIR5010 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000463802 -- 42,513,677(+) G/A upstream_transcript_variant
rs1001357081 -- 42,512,975(+) G/T upstream_transcript_variant
rs1001806869 -- 42,512,562(+) C/A upstream_transcript_variant
rs1003931293 -- 42,514,073(+) G/A upstream_transcript_variant
rs1004102905 -- 42,514,548(+) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5010 Gene

Variant ID Type Subtype PubMed ID
nsv1146669 OTHER inversion 26484159
nsv1064012 CNV gain 25217958
esv33998 OTHER inversion 15654335

Additional Variant Information for MIR5010 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5010

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5010 Gene

Disorders for MIR5010 Gene

Additional Disease Information for MIR5010

No disorders were found for MIR5010 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5010 Gene

Publications for MIR5010 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3 58
  4. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5010 Gene

Sources for MIR5010 Gene

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