microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR5010 Gene

Data sources for MIR5010 Gene:

RNA type for MIR5010 Gene

miRNA

Aliases for MIR5010 Gene

External Ids for MIR5010 Gene

Previous GeneCards Identifiers for MIR5010 Gene

  • GC17U901670
  • GC17P040671
  • GC17P042459

Summaries for MIR5010 Gene

Entrez Gene Summary for MIR5010 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5010 Gene

MIR5010 (MicroRNA 5010) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Insulin receptor recycling and Signaling by GPCR.

Additional gene information for MIR5010 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR5010 Gene

Genomics for MIR5010 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR5010 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5010 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR5010 Gene

Latest Assembly
chr17:42,514,188-42,514,307
(GRCh38/hg38)
Size:
120 bases
Orientation:
Plus strand

Previous Assembly
chr17:40,666,206-40,666,325
(GRCh37/hg19 by Entrez Gene)
Size:
120 bases
Orientation:
Plus strand

Genomic View for MIR5010 Gene

Genes around MIR5010 on UCSC Golden Path with GeneCards custom track
MIR5010 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR5010 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5010 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5010 Gene

Proteins for MIR5010 Gene

Post-translational modifications for MIR5010 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5010 Gene

Domains & Families for MIR5010 Gene

Gene Families for MIR5010 Gene

HGNC:
genes like me logo Genes that share domains with MIR5010: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR5010 Gene

Function for MIR5010 Gene

Phenotypes From GWAS Catalog for MIR5010 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5010 Gene

Localization for MIR5010 Gene

Gene Ontology (GO) - Cellular Components for MIR5010 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR5010: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR5010 Gene

Pathways & Interactions for MIR5010 Gene

genes like me logo Genes that share pathways with MIR5010: view

Pathways by source for MIR5010 Gene

Gene Ontology (GO) - Biological Process for MIR5010 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR5010 Gene

Drugs & Compounds for MIR5010 Gene

No Compound Related Data Available

Transcripts for MIR5010 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR5010 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000025C0E1_9606 miRNA 22 6

RefSeq: NR_049808,

LncBase: hsa-miR-5010-3p,

miRBase: MIMAT0021044,

MirGeneDB: Hsa-Mir-5010_3p,

TarBase: hsa-miR-5010-3p,

ENA: LM382884.1:1..22:ncRNA, LM611502.1:80..101:ncRNA,

URS000075B605_9606 precursor_RNA 120 4

RefSeq: NR_049808,

Ensembl: ENST00000582846 (view in UCSC) ,

miRBase: MI0017878,

ENA: LM611502.1:1..120:precursor_RNA,

URS00000ECE9C_9606 miRNA 22 4

RefSeq: NR_049808,

miRBase: MIMAT0021043,

MirGeneDB: Hsa-Mir-5010_5p,

ENA: LM382883.1:1..22:ncRNA, LM611502.1:21..42:ncRNA,

URS0000EFCD02_9606 precursor_RNA 82 1

MirGeneDB: Hsa-Mir-5010,

MIR5010 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR5010 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5010 Gene

No ASD Table

Relevant External Links for MIR5010 Gene

GeneLoc Exon Structure for
MIR5010

Expression for MIR5010 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR5010 Gene

genes like me logo Genes that share expression patterns with MIR5010: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5010 Gene

Orthologs for MIR5010 Gene

Evolution for MIR5010 Gene

ENSEMBL:
Gene Tree for MIR5010 (if available)
TreeFam:
Gene Tree for MIR5010 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR5010

No data available for Orthologs for MIR5010 Gene

Paralogs for MIR5010 Gene

No data available for Paralogs for MIR5010 Gene

Variants for MIR5010 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR5010 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR5010 Gene

Variant ID Type Subtype PubMed ID
esv33998 OTHER inversion 15654335
nsv1064012 CNV gain 25217958
nsv1146669 OTHER inversion 26484159

Additional Variant Information for MIR5010 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5010
Leiden Open Variation Database (LOVD)
MIR5010

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR5010 Gene

Disorders for MIR5010 Gene

Additional Disease Information for MIR5010

No disorders were found for MIR5010 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5010 Gene

Publications for MIR5010 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3
  4. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR5010 Gene

Sources for MIR5010 Gene