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Aliases for MIR501 Gene

Subcategory (RNA class) for MIR501 Gene


Quality Score for this RNA gene is


Aliases for MIR501 Gene

  • MicroRNA 501 2 3 5
  • Hsa-Mir-501 3
  • Mir-501 3
  • MIRN501 3

External Ids for MIR501 Gene

ORGUL Members for MIR501 Gene

Previous HGNC Symbols for MIR501 Gene

  • MIRN501

Previous GeneCards Identifiers for MIR501 Gene

  • GC0XP049667
  • GC0XP049776
  • GC0XP049781
  • GC0XP049783
  • GC0XP049786
  • GC0XP049789
  • GC0XP049792
  • GC0XP049796
  • GC0XP049806
  • GC0XP049836
  • GC0XP050010
  • GC0XP050015
  • GC0XP050018
  • GC0XP050021
  • GC0XP050024
  • GC0XP050027
  • GC0XP050030

Summaries for MIR501 Gene

Entrez Gene Summary for MIR501 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR501 Gene

MIR501 (MicroRNA 501) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR501 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR501 Gene

Genomics for MIR501 Gene

GeneHancer (GH) Regulatory Elements for MIR501 Gene

Promoters and enhancers for MIR501 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI049976 Enhancer 0.8 Ensembl ENCODE 11.8 -31.4 -31365 3 FEZF1 PRDM6 GATA3 POLR2A IKZF1 BCL6B PRDM10 PRDM4 TRIM28 TCF7L2 MIR532 MIR188 MIR362 MIR500A MIR500B MIR501 CLCN5 GC0XP049999 GC0XM049946
GH0XI049957 Enhancer 0.5 Ensembl ENCODE 12.5 -50.0 -50017 3.7 SPI1 MIR188 MIR532 MIR362 MIR500A MIR500B MIR501 CLCN5 GC0XM049946 GC0XP049999
GH0XI050034 Enhancer 0.2 ENCODE 13.8 +26.2 26228 2.3 MIR362 MIR500A MIR500B MIR501 MIR188 MIR532 CLCN5 GC0XP050039 PYY3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR501 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR501 Gene

Genomic Locations for MIR501 Gene
84 bases
Plus strand

Genomic View for MIR501 Gene

Genes around MIR501 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR501 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR501 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR501 Gene

Proteins for MIR501 Gene

Post-translational modifications for MIR501 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR501 Gene

Domains & Families for MIR501 Gene

Gene Families for MIR501 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR501: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR501 Gene

Function for MIR501 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR501 Gene

Localization for MIR501 Gene

Gene Ontology (GO) - Cellular Components for MIR501 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR501: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR501 Gene

Pathways & Interactions for MIR501 Gene

SuperPathways for MIR501 Gene

No Data Available

Interacting Proteins for MIR501 Gene

Gene Ontology (GO) - Biological Process for MIR501 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR501 Gene

Drugs & Compounds for MIR501 Gene

No Compound Related Data Available

Transcripts for MIR501 Gene

mRNA/cDNA for MIR501 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR501 Gene

No ASD Table

Relevant External Links for MIR501 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR501 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR501 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR501 Gene:

genes like me logo Genes that share expression patterns with MIR501: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR501 Gene

Orthologs for MIR501 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for MIR501 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-501 34
  • 100 (a)
(Mus musculus)
Mammalia Mir501 34
  • 67 (a)
Species where no ortholog for MIR501 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR501 Gene

Gene Tree for MIR501 (if available)
Gene Tree for MIR501 (if available)

Paralogs for MIR501 Gene

No data available for Paralogs for MIR501 Gene

Variants for MIR501 Gene

Sequence variations from dbSNP and Humsavar for MIR501 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1000551115 -- 50,009,618(+) T/C upstream_transcript_variant
rs1004397043 -- 50,009,098(+) T/C upstream_transcript_variant
rs1008396643 -- 50,007,929(+) A/G upstream_transcript_variant
rs1008448846 -- 50,008,466(+) G/T upstream_transcript_variant
rs1009204588 -- 50,010,277(+) G/A downstream_transcript_variant

Additional Variant Information for MIR501 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR501 Gene

Disorders for MIR501 Gene

Additional Disease Information for MIR501

No disorders were found for MIR501 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR501 Gene

Publications for MIR501 Gene

  1. The prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma. (PMID: 28122349) Ling Q … Zheng S (Oncotarget 2017) 3 58
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  3. Upregulation of miR-501-5p activates the wnt/β-catenin signaling pathway and enhances stem cell-like phenotype in gastric cancer. (PMID: 27846906) Fan D … Zhang Z (Journal of experimental & clinical cancer research : CR 2016) 3 58
  4. A Function Variant at miR-501 Alters Susceptibility to Hepatocellular Carcinoma in a Chinese Han Population. (PMID: 27310251) Liu Y … Tang J (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016) 3 58
  5. MiR-501-5p regulates CYLD expression and promotes cell proliferation in human hepatocellular carcinoma. (PMID: 25917358) Huang DH … Jiang N (Japanese journal of clinical oncology 2015) 3 58

Products for MIR501 Gene

Sources for MIR501 Gene

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