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Aliases for MIR5008 Gene

Subcategory (RNA class) for MIR5008 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR5008 Gene

  • MicroRNA 5008 2 3 5
  • Hsa-Mir-5008 3

External Ids for MIR5008 Gene

Previous GeneCards Identifiers for MIR5008 Gene

  • GC01U903345
  • GC01M228132

Summaries for MIR5008 Gene

Entrez Gene Summary for MIR5008 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5008 Gene

MIR5008 (MicroRNA 5008) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5008 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5008 Gene

Genomics for MIR5008 Gene

GeneHancer (GH) Regulatory Elements for MIR5008 Gene

Promoters and enhancers for MIR5008 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J227942 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 0.7 -4.0 -4034 6 ARNT SIN3A ZNF2 ZBTB7B ZNF48 YY1 ZNF121 GLIS2 ELK1 ARID2 WNT9A OBSCN-AS1 WNT3A OBSCN IBA57 ENSG00000269934 MRPL55 MIR5008
GH01J227933 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 +6.7 6685 2.6 ZNF473 INSM2 KLF17 STAT5A KLF14 ZEB1 FOS KLF13 ZNF174 SP3 ZNF678 CICP26 OBSCN OBSCN-AS1 C1orf35 JMJD4 CDC42BPA HIST3H3 MIR5008 WNT9A
GH01J227937 Enhancer 0.5 FANTOM5 0.7 +4.5 4505 0.1 GATA3 TARDBP DPF2 ARF1 MIR5008 WNT9A PRSS38
GH01J227915 Enhancer 0.8 ENCODE 0.3 +25.9 25868 0.2 ZNF473 KLF17 ZNF335 GLIS2 ZNF366 SCRT2 EGR2 ZNF680 ZNF398 ZFP69B JMJD4 MIR5008 PRSS38
GH01J227909 Enhancer 0.8 FANTOM5 ENCODE 0.3 +31.0 30977 1.8 KLF1 SP3 ZNF280D KLF17 NFXL1 MITF ZFHX2 ZNF341 WT1 ZBTB17 WNT3A MIR5008 PRSS38
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR5008 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5008 Gene

Genomic Locations for MIR5008 Gene
chr1:227,941,590-227,941,683
(GRCh38/hg38)
Size:
94 bases
Orientation:
Minus strand
chr1:228,129,291-228,129,384
(GRCh37/hg19)
Size:
94 bases
Orientation:
Minus strand

Genomic View for MIR5008 Gene

Genes around MIR5008 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5008 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5008 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5008 Gene

Function for MIR5008 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5008 Gene

Localization for MIR5008 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5008 Gene

Pathways & Interactions for MIR5008 Gene

SuperPathways for MIR5008 Gene

No Data Available

Interacting Proteins for MIR5008 Gene

Gene Ontology (GO) - Biological Process for MIR5008 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5008 Gene

Drugs & Compounds for MIR5008 Gene

No Compound Related Data Available

Transcripts for MIR5008 Gene

mRNA/cDNA for MIR5008 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5008 Gene

No ASD Table

Relevant External Links for MIR5008 Gene

GeneLoc Exon Structure for
MIR5008
ECgene alternative splicing isoforms for
MIR5008

Expression for MIR5008 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5008 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5008 Gene:

MIR5008
genes like me logo Genes that share expression patterns with MIR5008: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5008 Gene

Orthologs for MIR5008 Gene

Evolution for MIR5008 Gene

ENSEMBL:
Gene Tree for MIR5008 (if available)
TreeFam:
Gene Tree for MIR5008 (if available)

No data available for Orthologs for MIR5008 Gene

Paralogs for MIR5008 Gene

No data available for Paralogs for MIR5008 Gene

Variants for MIR5008 Gene

Sequence variations from dbSNP and Humsavar for MIR5008 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1001728115 -- 227,943,179(-) C/G upstream_transcript_variant
rs1002532055 -- 227,942,268(-) A/G upstream_transcript_variant
rs1004036457 -- 227,941,976(-) C/T upstream_transcript_variant
rs1005105121 -- 227,943,302(-) G/T upstream_transcript_variant
rs1008063633 -- 227,942,565(-) CCCCC/CCCCCC upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5008 Gene

Variant ID Type Subtype PubMed ID
esv32853 CNV gain 17666407
nsv516409 CNV loss 19592680
nsv523935 CNV loss 19592680
nsv826908 CNV gain 20364138
nsv952132 CNV deletion 24416366

Additional Variant Information for MIR5008 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5008

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5008 Gene

Disorders for MIR5008 Gene

Additional Disease Information for MIR5008

No disorders were found for MIR5008 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5008 Gene

Publications for MIR5008 Gene

  1. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5008 Gene

Sources for MIR5008 Gene

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