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Aliases for MIR5001 Gene

Subcategory (RNA class) for MIR5001 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5001 Gene

  • MicroRNA 5001 2 3 5
  • Hsa-Mir-5001 3
  • Mir-5001 3

External Ids for MIR5001 Gene

Previous GeneCards Identifiers for MIR5001 Gene

  • GC02U902458
  • GC02M233420

Summaries for MIR5001 Gene

Entrez Gene Summary for MIR5001 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5001 Gene

MIR5001 (MicroRNA 5001) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5001 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5001 Gene

Genomics for MIR5001 Gene

GeneHancer (GH) Regulatory Elements for MIR5001 Gene

Promoters and enhancers for MIR5001 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I232549 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 -0.2 -178 2.5 HDGF PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 TIGD1 PIR32753 MIR5001 EIF4E2 CHRNG PRSS56 PIR51534
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5001 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5001 Gene

Genomic Locations for MIR5001 Gene
chr2:232,550,474-232,550,573
(GRCh38/hg38)
Size:
100 bases
Orientation:
Minus strand
chr2:233,415,184-233,415,283
(GRCh37/hg19)

Genomic View for MIR5001 Gene

Genes around MIR5001 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5001 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5001 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5001 Gene

ORGUL Member Location for MIR5001 Gene

ORGUL Member Location for MIR5001 gene

Proteins for MIR5001 Gene

Post-translational modifications for MIR5001 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5001 Gene

Domains & Families for MIR5001 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5001 Gene

Function for MIR5001 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5001 Gene

Localization for MIR5001 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5001 Gene

Pathways & Interactions for MIR5001 Gene

SuperPathways for MIR5001 Gene

No Data Available

Interacting Proteins for MIR5001 Gene

Gene Ontology (GO) - Biological Process for MIR5001 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5001 Gene

Drugs & Compounds for MIR5001 Gene

No Compound Related Data Available

Transcripts for MIR5001 Gene

mRNA/cDNA for MIR5001 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5001 Gene

No ASD Table

Relevant External Links for MIR5001 Gene

GeneLoc Exon Structure for
MIR5001
ECgene alternative splicing isoforms for
MIR5001

Expression for MIR5001 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5001 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5001 Gene:

MIR5001
genes like me logo Genes that share expression patterns with MIR5001: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5001 Gene

Orthologs for MIR5001 Gene

Evolution for MIR5001 Gene

ENSEMBL:
Gene Tree for MIR5001 (if available)
TreeFam:
Gene Tree for MIR5001 (if available)

No data available for Orthologs for MIR5001 Gene

Paralogs for MIR5001 Gene

No data available for Paralogs for MIR5001 Gene

Variants for MIR5001 Gene

Sequence variations from dbSNP and Humsavar for MIR5001 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000310952 -- 232,550,728(-) A/G upstream_transcript_variant
rs1000378392 -- 232,550,562(-) C/A non_coding_transcript_variant
rs1000721434 -- 232,551,660(-) G/A upstream_transcript_variant
rs1001768561 -- 232,550,995(-) C/T upstream_transcript_variant
rs1003639313 -- 232,549,991(-) A/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5001 Gene

Variant ID Type Subtype PubMed ID
nsv3212 CNV deletion 18451855
nsv821918 CNV gain 20364138

Additional Variant Information for MIR5001 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5001

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5001 Gene

Disorders for MIR5001 Gene

Additional Disease Information for MIR5001

No disorders were found for MIR5001 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5001 Gene

Publications for MIR5001 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5001 Gene

Sources for MIR5001 Gene

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