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Aliases for MIR499B Gene

Subcategory (RNA class) for MIR499B Gene


Quality Score for this RNA gene is


Aliases for MIR499B Gene

  • MicroRNA 499b 2 3 5
  • MicroRNA 499a 2 3
  • Hsa-Mir-499a 3
  • Hsa-Mir-499b 3
  • MIR499A 3

External Ids for MIR499B Gene

Previous HGNC Symbols for MIR499B Gene

  • MIR499A

Previous GeneCards Identifiers for MIR499B Gene

  • GC20U900708
  • GC20M033582

Summaries for MIR499B Gene

Entrez Gene Summary for MIR499B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR499B Gene

MIR499B (MicroRNA 499b) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR499B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR499B Gene

Genomics for MIR499B Gene

Genomic Locations for MIR499B Gene

Genomic Locations for MIR499B Gene
73 bases
Minus strand

Genomic View for MIR499B Gene

Genes around MIR499B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR499B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR499B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR499B Gene

ORGUL Member Location for MIR499B Gene

ORGUL Member Location for MIR499B gene

No data available for GeneHancer (GH) Regulatory Elements for MIR499B Gene

Proteins for MIR499B Gene

Post-translational modifications for MIR499B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR499B Gene

Domains & Families for MIR499B Gene

Gene Families for MIR499B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR499B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR499B Gene

Function for MIR499B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR499B Gene

Localization for MIR499B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR499B Gene

Pathways & Interactions for MIR499B Gene

SuperPathways for MIR499B Gene

No Data Available

Interacting Proteins for MIR499B Gene

Gene Ontology (GO) - Biological Process for MIR499B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR499B Gene

Drugs & Compounds for MIR499B Gene

No Compound Related Data Available

Transcripts for MIR499B Gene

mRNA/cDNA for MIR499B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR499B Gene

No ASD Table

Relevant External Links for MIR499B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR499B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR499B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR499B Gene

Orthologs for MIR499B Gene

Evolution for MIR499B Gene

Gene Tree for MIR499B (if available)
Gene Tree for MIR499B (if available)

No data available for Orthologs for MIR499B Gene

Paralogs for MIR499B Gene

No data available for Paralogs for MIR499B Gene

Variants for MIR499B Gene

Sequence variations from dbSNP and Humsavar for MIR499B Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000122977 -- 34,992,123(-) C/T upstream_transcript_variant
rs1000523139 -- 34,991,871(-) G/A upstream_transcript_variant
rs1001022981 -- 34,991,986(-) G/A upstream_transcript_variant
rs1001077088 -- 34,990,556(-) G/C upstream_transcript_variant
rs1002631481 -- 34,990,244(-) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR499B Gene

Variant ID Type Subtype PubMed ID
nsv1055447 CNV loss 25217958
nsv1063673 CNV loss 25217958
nsv3362 CNV insertion 18451855
nsv833962 CNV loss 17160897

Additional Variant Information for MIR499B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR499B Gene

Disorders for MIR499B Gene

Additional Disease Information for MIR499B

No disorders were found for MIR499B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR499B Gene

Publications for MIR499B Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR499B Gene

Sources for MIR499B Gene

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