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Aliases for MIR4999 Gene

Subcategory (RNA class) for MIR4999 Gene


Quality Score for this RNA gene is


Aliases for MIR4999 Gene

  • MicroRNA 4999 2 3 5
  • Hsa-Mir-4999 3
  • Mir-4999 3

External Ids for MIR4999 Gene

Previous GeneCards Identifiers for MIR4999 Gene

  • GC19U901577
  • GC19M008456

Summaries for MIR4999 Gene

Entrez Gene Summary for MIR4999 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4999 Gene

MIR4999 (MicroRNA 4999) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4999 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4999 Gene

Genomics for MIR4999 Gene

GeneHancer (GH) Regulatory Elements for MIR4999 Gene

Promoters and enhancers for MIR4999 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I008387 Enhancer 0.9 ENCODE dbSUPER 550.8 +2.0 1992 0.5 ETV1 BACH1 PYGO2 ZBTB40 RELA IRF9 POLR2A ADNP ZNF639 CAVIN1 MIR4999 ZNF558 ZNF699 HNRNPM ELAVL1 ZNF559 ZNF317 XAB2 ENSG00000269300 ANGPTL4
GH19I008388 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 0.8 -3.5 -3464 10.3 MLX IRF4 YY1 ZNF213 E2F8 ZNF143 ZNF548 SP3 NFYC GLIS1 RAB11B HNRNPM ELAVL1 ZNF699 ZNF558 XAB2 ZNF317 ENSG00000269300 MAP2K7 MARCH2
GH19I008361 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.3 +26.0 25971 3.6 FOXA2 PKNOX1 ARNT ZFP64 ARID4B SIN3A YY1 FOS DEK ZC3H11A ANGPTL4 HNRNPM ZNF317 XAB2 ZNF699 ZNF558 MAP2K7 ELAVL1 ZNF559 ZNF414
GH19I008385 Enhancer 0.7 ENCODE dbSUPER 0.8 +3.6 3559 0.9 ZNF280A SMARCE1 MEIS2 PKNOX1 CEBPG ANGPTL4 MIR4999 RAB11B-AS1
GH19I008370 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 +18.4 18370 1.5 HDGF PKNOX1 ATF1 ARNT TCF12 POLR2B GATA2 NCOA1 ZNF592 GMEB1 MARCH2 ANGPTL4 MIR4999
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4999 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4999 Gene

Genomic Locations for MIR4999 Gene
91 bases
Minus strand

Genomic View for MIR4999 Gene

Genes around MIR4999 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4999 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4999 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4999 Gene

ORGUL Member Location for MIR4999 Gene

ORGUL Member Location for MIR4999 gene

Proteins for MIR4999 Gene

Post-translational modifications for MIR4999 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4999 Gene

Domains & Families for MIR4999 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4999 Gene

Function for MIR4999 Gene

Phenotypes From GWAS Catalog for MIR4999 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4999 Gene

Localization for MIR4999 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4999 Gene

Pathways & Interactions for MIR4999 Gene

SuperPathways for MIR4999 Gene

No Data Available

Interacting Proteins for MIR4999 Gene

Gene Ontology (GO) - Biological Process for MIR4999 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4999 Gene

Drugs & Compounds for MIR4999 Gene

No Compound Related Data Available

Transcripts for MIR4999 Gene

mRNA/cDNA for MIR4999 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4999 Gene

No ASD Table

Relevant External Links for MIR4999 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4999 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4999 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4999 Gene:

genes like me logo Genes that share expression patterns with MIR4999: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4999 Gene

Orthologs for MIR4999 Gene

Evolution for MIR4999 Gene

Gene Tree for MIR4999 (if available)
Gene Tree for MIR4999 (if available)

No data available for Orthologs for MIR4999 Gene

Paralogs for MIR4999 Gene

No data available for Paralogs for MIR4999 Gene

Variants for MIR4999 Gene

Sequence variations from dbSNP and Humsavar for MIR4999 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000080334 -- 8,390,701(-) G/A upstream_transcript_variant
rs1000346951 -- 8,389,922(-) A/T upstream_transcript_variant
rs1001965475 -- 8,389,547(-) G/T upstream_transcript_variant
rs1003063002 -- 8,389,332(-) A/G non_coding_transcript_variant
rs1004450485 -- 8,390,217(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4999 Gene

Variant ID Type Subtype PubMed ID
esv3643614 CNV gain 21293372

Additional Variant Information for MIR4999 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4999 Gene

Disorders for MIR4999 Gene

Additional Disease Information for MIR4999

No disorders were found for MIR4999 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4999 Gene

Publications for MIR4999 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4999 Gene

Sources for MIR4999 Gene

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