microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4794 Gene

Data sources for MIR4794 Gene:

Subcategory (RNA class) for MIR4794 Gene

miRNA

Aliases for MIR4794 Gene

External Ids for MIR4794 Gene

Previous GeneCards Identifiers for MIR4794 Gene

  • GC01U903277
  • GC01P065047

Summaries for MIR4794 Gene

Entrez Gene Summary for MIR4794 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4794 Gene

MIR4794 (MicroRNA 4794) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4794 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4794 Gene

Genomics for MIR4794 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4794 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J064580 Enhancer 0.4 Ensembl 250.7 +1.7 1654 1 ZSCAN16 PRDM6 ZNF26 CEBPB MIR4794 ITGB3BP MN308948 CACHD1 RAVER2
GH01J064595 Enhancer 1.4 UCNEbase Ensembl ENCODE CraniofacialAtlas 0.4 +16.7 16654 4.6 FEZF1 CEBPB FOXA2 EP300 KLF7 ZNF843 STAT3 BCL6 BCL11B TCF7L2 CACHD1 MIR4794 MN308948 RAVER2
GH01J064571 Enhancer 1 Ensembl ENCODE CraniofacialAtlas 0.4 -6.7 -6747 7.4 ZIC2 ZNF341 YY1 SPI1 SCRT1 ZBTB40 SP7 ZFP69B TRIM28 KLF1 CACHD1 MIR4794 HSALNG0004160 RAVER2
GH01J064538 Enhancer 1 ENCODE CraniofacialAtlas dbSUPER 0.3 -40.1 -40050 4.2 ZNF341 ZNF843 FOXA2 PRDM6 HNF4A RAD21 SP7 SP1 PRDM4 PKNOX1 CACHD1 HSALNG0004160 MIR4794 RAVER2
GH01J064536 Enhancer 1 ENCODE CraniofacialAtlas dbSUPER 0.3 -42.7 -42695 0.9 FEZF1 RXRA FOXA2 ZBTB33 JUND KLF16 HNF4A FOXA1 RAD21 REST CACHD1 HSALNG0004160 MIR4794 RAVER2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4794 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4794 Gene

Latest Assembly
chr1:64,579,847-64,579,923
(GRCh38/hg38)
Size:
77 bases
Orientation:
Plus strand

Previous Assembly
chr1:65,045,530-65,045,606
(GRCh37/hg19 by Entrez Gene)
Size:
77 bases
Orientation:
Plus strand

chr1:65,045,530-65,045,606
(GRCh37/hg19 by Ensembl)
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR4794 Gene

Genes around MIR4794 on UCSC Golden Path with GeneCards custom track
MIR4794 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4794 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4794 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4794 Gene

Proteins for MIR4794 Gene

Post-translational modifications for MIR4794 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4794 Gene

Domains & Families for MIR4794 Gene

Gene Families for MIR4794 Gene

HGNC:
genes like me logo Genes that share domains with MIR4794: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4794 Gene

Function for MIR4794 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4794 Gene

Localization for MIR4794 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4794 Gene

Pathways & Interactions for MIR4794 Gene

PathCards logo

SuperPathways for MIR4794 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4794 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4794 Gene

Drugs & Compounds for MIR4794 Gene

No Compound Related Data Available

Transcripts for MIR4794 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4794 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E9B5_9606 precursor_RNA 77 3

RefSeq: NR_039957,

Ensembl: ENST00000582305 (view in UCSC) ,

miRBase: MI0017441,

URS00003EAB10_9606 miRNA 22 3

RefSeq: NR_039957,

miRBase: MIMAT0019967,

ENA: FR773119.1:1..22:ncRNA,

MIR4794 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4794 Gene

No ASD Table

Relevant External Links for MIR4794 Gene

GeneLoc Exon Structure for
MIR4794

No data available for mRNA/cDNA for MIR4794 Gene

Expression for MIR4794 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4794 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4794

genes like me logo Genes that share expression patterns with MIR4794: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4794 Gene

Orthologs for MIR4794 Gene

Evolution for MIR4794 Gene

ENSEMBL:
Gene Tree for MIR4794 (if available)
TreeFam:
Gene Tree for MIR4794 (if available)

No data available for Orthologs for MIR4794 Gene

Paralogs for MIR4794 Gene

No data available for Paralogs for MIR4794 Gene

Variants for MIR4794 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4794 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4794 Gene

Variant ID Type Subtype PubMed ID
esv2660804 CNV deletion 23128226
esv3586268 CNV loss 21293372

Additional Variant Information for MIR4794 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4794

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4794 Gene

Disorders for MIR4794 Gene

Additional Disease Information for MIR4794

No disorders were found for MIR4794 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4794 Gene

Publications for MIR4794 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4794 Gene

Sources for MIR4794 Gene