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Aliases for MIR4785 Gene

Subcategory (RNA class) for MIR4785 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4785 Gene

  • MicroRNA 4785 2 3 5
  • Hsa-Mir-4785 3
  • Mir-4785 3

External Ids for MIR4785 Gene

Previous GeneCards Identifiers for MIR4785 Gene

  • GC02U902434
  • GC02M161266
  • GC02M160273

Summaries for MIR4785 Gene

Entrez Gene Summary for MIR4785 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4785 Gene

MIR4785 (MicroRNA 4785) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4785 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4785 Gene

Genomics for MIR4785 Gene

GeneHancer (GH) Regulatory Elements for MIR4785 Gene

Promoters and enhancers for MIR4785 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I160401 Promoter/Enhancer 1.6 Ensembl ENCODE dbSUPER 0.8 +2.1 2146 7.9 ARID4B SIN3A DMAP1 ZNF48 FOS ZNF585B MXD3 PRDM4 CTCF KLF1 ITGB6 BAZ2B RBMS1 PLA2R1 MIR4785 GC02M160337
GH02I160410 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.8 -3.7 -3681 2.1 JUND JUN NR2F6 NR2F2 ITGB6 RBMS1 MIR4785 LOC100419108
GH02I160384 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +19.1 19081 8.4 KLF17 SIN3A MZF1 FEZF1 ZBTB40 ZNF366 ZSCAN5C FOS RXRA CEBPB ITGB6 PLA2R1 MIR4785 GC02M160337 RBMS1
GH02I160415 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -10.5 -10509 5.4 RFX1 PKNOX1 JUN ZSCAN4 ZEB2 ATF2 OSR2 SP1 JUND PRDM6 ITGB6 RBMS1 PLA2R1 LY75 MIR4785 LOC100419108
GH02I160363 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +34.7 34721 19.5 FEZF1 RFX5 SCRT2 ZNF680 ZBTB11 CEBPB REST NR2F2 SP1 PRDM6 ITGB6 RBMS1 PLA2R1 GC02M160337 MIR4785
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4785 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4785 Gene

Genomic Locations for MIR4785 Gene
chr2:160,407,810-160,407,882
(GRCh38/hg38)
Size:
73 bases
Orientation:
Minus strand
chr2:161,264,321-161,264,393
(GRCh37/hg19)

Genomic View for MIR4785 Gene

Genes around MIR4785 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4785 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4785 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4785 Gene

ORGUL Member Location for MIR4785 Gene

ORGUL Member Location for MIR4785 gene

Proteins for MIR4785 Gene

Post-translational modifications for MIR4785 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4785 Gene

Domains & Families for MIR4785 Gene

Gene Families for MIR4785 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4785: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4785 Gene

Function for MIR4785 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4785 Gene

Localization for MIR4785 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4785 Gene

Pathways & Interactions for MIR4785 Gene

SuperPathways for MIR4785 Gene

No Data Available

Interacting Proteins for MIR4785 Gene

Gene Ontology (GO) - Biological Process for MIR4785 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4785 Gene

Drugs & Compounds for MIR4785 Gene

No Compound Related Data Available

Transcripts for MIR4785 Gene

mRNA/cDNA for MIR4785 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4785 Gene

No ASD Table

Relevant External Links for MIR4785 Gene

GeneLoc Exon Structure for
MIR4785
ECgene alternative splicing isoforms for
MIR4785

Expression for MIR4785 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4785 Gene:

MIR4785
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4785 Gene

Orthologs for MIR4785 Gene

Evolution for MIR4785 Gene

ENSEMBL:
Gene Tree for MIR4785 (if available)
TreeFam:
Gene Tree for MIR4785 (if available)

No data available for Orthologs for MIR4785 Gene

Paralogs for MIR4785 Gene

No data available for Paralogs for MIR4785 Gene

Variants for MIR4785 Gene

Sequence variations from dbSNP and Humsavar for MIR4785 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000610508 -- 160,408,025(-) C/G upstream_transcript_variant
rs1000674622 -- 160,408,823(-) A/G upstream_transcript_variant
rs1000721612 -- 160,409,387(-) G/A upstream_transcript_variant
rs1001048173 -- 160,407,856(-) G/A non_coding_transcript_variant
rs1003167058 -- 160,409,808(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4785 Gene

Variant ID Type Subtype PubMed ID
nsv1143963 CNV deletion 24896259
nsv2998 CNV insertion 18451855

Additional Variant Information for MIR4785 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4785

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4785 Gene

Disorders for MIR4785 Gene

Additional Disease Information for MIR4785

No disorders were found for MIR4785 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4785 Gene

Publications for MIR4785 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4785 Gene

Sources for MIR4785 Gene

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