microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4784 Gene

Data sources for MIR4784 Gene:

RNA type for MIR4784 Gene

miRNA

Aliases for MIR4784 Gene

External Ids for MIR4784 Gene

Previous GeneCards Identifiers for MIR4784 Gene

  • GC02U902417
  • GC02M132300
  • GC02M132313
  • GC02M132334

Summaries for MIR4784 Gene

Entrez Gene Summary for MIR4784 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4784 Gene

MIR4784 (MicroRNA 4784) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4784 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4784 Gene

Genomics for MIR4784 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4784 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J131490 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 -1.8 -1765 4.8 SP1 ZNF207 NCOR1 MYC ZNF580 ZNF592 ATF2 ZNF223 ZNF10 BRCA1 SMPD4BP MZT2A HSALNG0018894 MIR4784 lnc-RAB6D-1 lnc-TUBA3D-1 ENSG00000272769 TUBA3D
GH02J131488 Enhancer 0.5 dbSUPER 0.7 +2.4 2414 1.1 REST KLF9 EGR1 ZBTB33 EGR2 POLR2A MZT2A HSALNG0018894 MIR4784 lnc-RAB6D-1 TUBA3D
GH02J131478 Enhancer 0.3 dbSUPER 0.4 +12.5 12512 0.9 NCOA3 FOS SMPD4BP MZT2A TUBA3D MIR4784
GH02J131479 Enhancer 0.2 dbSUPER 0.4 +11.8 11793 0.4 MZT2A TUBA3D MIR4784
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4784 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4784 Gene

Latest Assembly
chr2:131,491,160-131,491,236
(GRCh38/hg38)
Size:
77 bases
Orientation:
Minus strand

Previous Assembly
chr2:132,248,733-132,248,809
(GRCh37/hg19 by Entrez Gene)
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR4784 Gene

Genes around MIR4784 on UCSC Golden Path with GeneCards custom track
MIR4784 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4784 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4784 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4784 Gene

Proteins for MIR4784 Gene

Post-translational modifications for MIR4784 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4784 Gene

Domains & Families for MIR4784 Gene

Gene Families for MIR4784 Gene

HGNC:
genes like me logo Genes that share domains with MIR4784: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4784 Gene

Function for MIR4784 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4784 Gene

Localization for MIR4784 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4784 Gene

Pathways & Interactions for MIR4784 Gene

PathCards logo

SuperPathways for MIR4784 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4784 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4784 Gene

Drugs & Compounds for MIR4784 Gene

No Compound Related Data Available

Transcripts for MIR4784 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4784 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075A4F6_9606 precursor_RNA 77 3

RefSeq: NR_039945,

Ensembl: ENST00000579560 (view in UCSC) ,

miRBase: MI0017429,

URS000021E7E5_9606 miRNA 20 3

RefSeq: NR_039945,

miRBase: MIMAT0019948,

ENA: FR773104.1:1..20:ncRNA,

MIR4784 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4784 Gene

No ASD Table

Relevant External Links for MIR4784 Gene

GeneLoc Exon Structure for
MIR4784

No data available for mRNA/cDNA for MIR4784 Gene

Expression for MIR4784 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4784 Gene

genes like me logo Genes that share expression patterns with MIR4784: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4784 Gene

Orthologs for MIR4784 Gene

Evolution for MIR4784 Gene

ENSEMBL:
Gene Tree for MIR4784 (if available)
TreeFam:
Gene Tree for MIR4784 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR4784

No data available for Orthologs for MIR4784 Gene

Paralogs for MIR4784 Gene

No data available for Paralogs for MIR4784 Gene

Variants for MIR4784 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4784 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4784 Gene

Variant ID Type Subtype PubMed ID
dgv4075n100 CNV gain 25217958
dgv4077n100 CNV gain 25217958
dgv4079n100 CNV loss 25217958
dgv4080n100 CNV gain 25217958
dgv476n27 CNV loss 19166990
esv2670824 CNV deletion 23128226
esv2759092 CNV gain+loss 17122850
esv2760576 CNV gain+loss 21179565
esv34412 CNV gain 17911159
esv34704 CNV gain 17911159
esv3575300 CNV gain 25503493
esv3584079 CNV loss 25503493
esv3592483 CNV loss 21293372
esv3592484 CNV gain 21293372
esv3893359 CNV gain+loss 25118596
nsv1002963 CNV gain 25217958
nsv1006738 CNV gain 25217958
nsv1008539 CNV gain 25217958
nsv1014682 CNV loss 25217958
nsv428404 CNV loss 18775914
nsv459396 CNV gain 19166990
nsv470486 CNV loss 18288195
nsv524021 CNV loss 19592680
nsv583140 CNV gain 21841781
nsv583143 CNV gain+loss 21841781
nsv583145 CNV loss 21841781
nsv7327 OTHER inversion 18451855
nsv834376 CNV gain 17160897
nsv979124 CNV duplication 23825009
nsv997248 CNV loss 25217958

Additional Variant Information for MIR4784 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4784
Leiden Open Variation Database (LOVD)
MIR4784

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4784 Gene

Disorders for MIR4784 Gene

Additional Disease Information for MIR4784

No disorders were found for MIR4784 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4784 Gene

Publications for MIR4784 Gene

  1. LINC01133 promotes the progression of cervical cancer by sponging miR-4784 to up-regulate AHDC1. (PMID: 31390932) Feng Y … Liu C (Cancer biology & therapy 2019) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4784 Gene

Sources for MIR4784 Gene