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Aliases for MIR4783 Gene

Subcategory (RNA class) for MIR4783 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4783 Gene

  • MicroRNA 4783 2 3 5
  • Hsa-Mir-4783 3

External Ids for MIR4783 Gene

Previous GeneCards Identifiers for MIR4783 Gene

  • GC02U902423
  • GC02M128184

Summaries for MIR4783 Gene

Entrez Gene Summary for MIR4783 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4783 Gene

MIR4783 (MicroRNA 4783) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4783 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4783 Gene

Genomics for MIR4783 Gene

GeneHancer (GH) Regulatory Elements for MIR4783 Gene

Promoters and enhancers for MIR4783 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I127422 Enhancer 0.9 Ensembl dbSUPER 550.8 +0.6 599 2 CTCF KLF1 MXI1 ZNF223 MAX SIN3A ZIC2 E2F1 ZNF335 GLIS2 MIR4783 ENSG00000236682 MAP3K2 PROC
GH02I127419 Promoter 0.9 EPDnew 0.8 +3.9 3940 0.1 DRAP1 PKNOX1 NFYC EBF1 REST RAD21 ETS1 SREBF1 POLR2A BCL6 PROC MIR4783 GC02P127379
GH02I127418 Promoter 1.2 EPDnew 0.4 +5.2 5205 0.1 FOXA2 NFRKB ZFP64 ARID4B DMAP1 RAD21 THRB ZNF48 ZSCAN9 RARA PROC MIR4783 GC02P127379
GH02I127437 Enhancer 0.9 ENCODE 0.4 -14.8 -14752 1.3 FOXA2 MLX ARID4B DMAP1 ZNF48 ETS1 YY1 SLC30A9 RXRA SP5 ERCC3 ENSG00000236682 MAP3K2 RNU4-48P BIN1 LIMS2 MIR4783 ENSG00000231731 LOC105373608 IWS1
GH02I127454 Enhancer 1.2 Ensembl ENCODE 0.3 -31.7 -31743 2.6 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF48 ETS1 YY1 SLC30A9 ENSG00000231731 PROC LIMS2 ERCC3 MAP3K2 ENSG00000236682 LOC105373608 MIR4783 IWS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4783 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4783 Gene

Genomic Locations for MIR4783 Gene
chr2:127,423,537-127,423,618
(GRCh38/hg38)
Size:
82 bases
Orientation:
Minus strand
chr2:128,181,113-128,181,194
(GRCh37/hg19)

Genomic View for MIR4783 Gene

Genes around MIR4783 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4783 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4783 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4783 Gene

ORGUL Member Location for MIR4783 Gene

ORGUL Member Location for MIR4783 gene

Proteins for MIR4783 Gene

Post-translational modifications for MIR4783 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4783 Gene

Domains & Families for MIR4783 Gene

Gene Families for MIR4783 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4783: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4783 Gene

Function for MIR4783 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4783 Gene

Localization for MIR4783 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4783 Gene

Pathways & Interactions for MIR4783 Gene

SuperPathways for MIR4783 Gene

No Data Available

Interacting Proteins for MIR4783 Gene

Gene Ontology (GO) - Biological Process for MIR4783 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4783 Gene

Drugs & Compounds for MIR4783 Gene

No Compound Related Data Available

Transcripts for MIR4783 Gene

mRNA/cDNA for MIR4783 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4783 Gene

No ASD Table

Relevant External Links for MIR4783 Gene

GeneLoc Exon Structure for
MIR4783
ECgene alternative splicing isoforms for
MIR4783

Expression for MIR4783 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4783 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4783 Gene:

MIR4783
genes like me logo Genes that share expression patterns with MIR4783: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4783 Gene

Orthologs for MIR4783 Gene

Evolution for MIR4783 Gene

ENSEMBL:
Gene Tree for MIR4783 (if available)
TreeFam:
Gene Tree for MIR4783 (if available)

No data available for Orthologs for MIR4783 Gene

Paralogs for MIR4783 Gene

No data available for Paralogs for MIR4783 Gene

Variants for MIR4783 Gene

Sequence variations from dbSNP and Humsavar for MIR4783 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs116738363 likely-benign, Thrombophilia, hereditary, due to protein C deficiency, autosomal dominant 127,423,184(-) G/A downstream_transcript_variant
rs121918159 pathogenic, Thrombophilia, hereditary, due to protein C deficiency, autosomal dominant 127,423,319(-) A/C downstream_transcript_variant
rs200045749 likely-benign, Thrombophilia, hereditary, due to protein C deficiency, autosomal dominant 127,423,170(-) C/T downstream_transcript_variant
rs200234655 uncertain-significance, Thrombophilia, hereditary, due to protein C deficiency, autosomal dominant 127,423,093(-) C/A/G downstream_transcript_variant
rs374476971 uncertain-significance, Thrombophilia, hereditary, due to protein C deficiency, autosomal dominant 127,423,111(-) G/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4783 Gene

Variant ID Type Subtype PubMed ID
nsv583036 CNV gain 21841781

Additional Variant Information for MIR4783 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4783

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4783 Gene

Disorders for MIR4783 Gene

Additional Disease Information for MIR4783

No disorders were found for MIR4783 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4783 Gene

Publications for MIR4783 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4783 Gene

Sources for MIR4783 Gene

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