microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4778 Gene

Subcategory (RNA class) for MIR4778 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR4778 Gene

  • MicroRNA 4778 2 3 5
  • Hsa-Mir-4778 2 3
  • MIR4778 2 5
  • MIMAT0019936 50
  • MIMAT0019937 50
  • MI0017422 50

External Ids for MIR4778 Gene

Previous GeneCards Identifiers for MIR4778 Gene

  • GC02U902415
  • GC02M066588

Summaries for MIR4778 Gene

Entrez Gene Summary for MIR4778 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4778 Gene

MIR4778 (MicroRNA 4778) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4778 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4778 Gene

Genomics for MIR4778 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4778 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J066364 Enhancer 1 Ensembl ENCODE 0.4 -6.4 -6431 1.5 PRDM10 ZNF629 ZNF692 PRDM1 ZSCAN4 ZNF501 HDAC1 ZBTB44 ZNF639 KLF7 HSALNG0015581 MIR4778 MEIS1 SPRED2
GH02J066361 Enhancer 0.4 Ensembl 0.7 -4.5 -4473 1.6 POLR2A EZH2 TRIM28 HSALNG0015581 MIR4778 MEIS1 SPRED2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4778 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4778 Gene

Genomic Locations for MIR4778 Gene
chr2:66,358,249-66,358,328
(GRCh38/hg38)
Size:
80 bases
Orientation:
Minus strand
chr2:66,585,381-66,585,460
(GRCh37/hg19)
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR4778 Gene

Genes around MIR4778 on UCSC Golden Path with GeneCards custom track
MIR4778 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4778 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4778 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4778 Gene

Proteins for MIR4778 Gene

Post-translational modifications for MIR4778 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4778 Gene

Domains & Families for MIR4778 Gene

Gene Families for MIR4778 Gene

HGNC:
genes like me logo Genes that share domains with MIR4778: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4778 Gene

Function for MIR4778 Gene

Phenotypes From GWAS Catalog for MIR4778 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4778 Gene

Localization for MIR4778 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4778 Gene

Pathways & Interactions for MIR4778 Gene

PathCards logo

SuperPathways for MIR4778 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4778 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4778 Gene

Drugs & Compounds for MIR4778 Gene

No Compound Related Data Available

Transcripts for MIR4778 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4778 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D462_9606 precursor_RNA 80 4

HGNC: 41648,

RefSeq: NR_039938,

Ensembl: ENST00000577635 (view in UCSC) ,

miRBase: MI0017422,

URS00000AAE32_9606 miRNA 22 3

RefSeq: NR_039938,

miRBase: MIMAT0019936,

ENA: FR773095.1:1..22:ncRNA,

URS00000DEF85_9606 miRNA 22 3

RefSeq: NR_039938,

miRBase: MIMAT0019937,

ENA: FR773094.1:1..22:ncRNA,

MIR4778 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4778 Gene

No ASD Table

Relevant External Links for MIR4778 Gene

GeneLoc Exon Structure for
MIR4778

No data available for mRNA/cDNA for MIR4778 Gene

Expression for MIR4778 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4778 Gene

genes like me logo Genes that share expression patterns with MIR4778: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4778 Gene

Orthologs for MIR4778 Gene

Evolution for MIR4778 Gene

ENSEMBL:
Gene Tree for MIR4778 (if available)
TreeFam:
Gene Tree for MIR4778 (if available)

No data available for Orthologs for MIR4778 Gene

Paralogs for MIR4778 Gene

No data available for Paralogs for MIR4778 Gene

Variants for MIR4778 Gene

Additional dbSNP identifiers (rs#s) for MIR4778 Gene

Additional Variant Information for MIR4778 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4778

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4778 Gene

Disorders for MIR4778 Gene

No disorders were found for MIR4778 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4778 Gene

Publications for MIR4778 Gene

  1. Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2. (PMID: 24322204) Winham SJ … Biernacka JM (Molecular psychiatry 2014) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4778 Gene

Sources for MIR4778 Gene