microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4772 Gene

Subcategory (RNA class) for MIR4772 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR4772 Gene

  • MicroRNA 4772 2 3 5
  • Hsa-MiR-4772-3p 166 177
  • Hsa-MiR-4772-5p 177
  • Hsa-Mir-4772 3
  • MIMAT0019927 51
  • MIMAT0019926 51
  • MI0017414 51
  • Mir-4772 3
  • MIR4772 2

External Ids for MIR4772 Gene

Previous GeneCards Identifiers for MIR4772 Gene

  • GC02U902426
  • GC02P103052

Summaries for MIR4772 Gene

Entrez Gene Summary for MIR4772 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4772 Gene

MIR4772 (MicroRNA 4772) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4772 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4772 Gene

Genomics for MIR4772 Gene

GeneHancer (GH) Regulatory Elements for MIR4772 Gene

Promoters and enhancers for MIR4772 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J102416 Promoter/Enhancer 1.8 EPDnew FANTOM5 Ensembl ENCODE 0.4 -12.6 -12629 6.2 GTF2E2 ZBTB11 AFF1 HES1 MYC TOE1 RUNX1 CTBP1 NCOR1 RELA IL18RAP ENSG00000234389 IL1R2 MIR4772
GH02J102424 Enhancer 0.9 FANTOM5 ENCODE 0.4 -6.8 -6842 1.8 EP300 JUND BCL11A TCF12 MEF2B SPI1 BATF IRF4 IKZF1 CEBPG ENSG00000234389 IL1R2 IL18RAP SLC9A4 IL18R1 IL1R1 MIR4772
GH02J102425 Promoter 0.6 EPDnew 0.4 -9.1 -9148 0.1 GTF2E2 ZBTB11 LEF1 SPI1 ZNF589 IL18RAP MIR4772
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4772 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4772 Gene

Genomic Locations for MIR4772 Gene
chr2:102,432,289-102,432,366
(GRCh38/hg38)
Size:
78 bases
Orientation:
Plus strand
chr2:103,048,749-103,048,826
(GRCh37/hg19)
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR4772 Gene

Genes around MIR4772 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4772 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4772 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4772 Gene

Proteins for MIR4772 Gene

Post-translational modifications for MIR4772 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4772 Gene

Domains & Families for MIR4772 Gene

Gene Families for MIR4772 Gene

HGNC:
genes like me logo Genes that share domains with MIR4772: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4772 Gene

Function for MIR4772 Gene

Phenotypes From GWAS Catalog for MIR4772 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4772 Gene

Localization for MIR4772 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR4772 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4772 Gene

Pathways & Interactions for MIR4772 Gene

PathCards logo

SuperPathways for MIR4772 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR4772 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4772 Gene

Drugs & Compounds for MIR4772 Gene

No Compound Related Data Available

Transcripts for MIR4772 Gene

mRNA/cDNA for MIR4772 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
6 ENA transcripts :
1 LncBase transcripts :
2 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4772 Gene

No ASD Table

Relevant External Links for MIR4772 Gene

GeneLoc Exon Structure for
MIR4772

Expression for MIR4772 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4772 Gene

genes like me logo Genes that share expression patterns with MIR4772: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4772 Gene

Orthologs for MIR4772 Gene

Evolution for MIR4772 Gene

ENSEMBL:
Gene Tree for MIR4772 (if available)
TreeFam:
Gene Tree for MIR4772 (if available)

No data available for Orthologs for MIR4772 Gene

Paralogs for MIR4772 Gene

No data available for Paralogs for MIR4772 Gene

Variants for MIR4772 Gene

Additional dbSNP identifiers (rs#s) for MIR4772 Gene

Additional Variant Information for MIR4772 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4772

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4772 Gene

Disorders for MIR4772 Gene

Additional Disease Information for MIR4772

No disorders were found for MIR4772 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4772 Gene

Publications for MIR4772 Gene

  1. Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer. (PMID: 27788488) Liu C … Li D (Oncotarget 2016) 3 54
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 54
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 54
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR4772 Gene

Sources for MIR4772 Gene