microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4772 Gene

Data sources for MIR4772 Gene:

Subcategory (RNA class) for MIR4772 Gene

miRNA

Aliases for MIR4772 Gene

External Ids for MIR4772 Gene

Previous GeneCards Identifiers for MIR4772 Gene

  • GC02U902426
  • GC02P103052

Summaries for MIR4772 Gene

Entrez Gene Summary for MIR4772 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4772 Gene

MIR4772 (MicroRNA 4772) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4772 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4772 Gene

Genomics for MIR4772 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4772 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J102416 Promoter/Enhancer 1.8 EPDnew FANTOM5 Ensembl ENCODE 0.4 -12.6 -12629 6.2 MNT IKZF1 IRF2 HES1 BHLHE40 ARNT ZNF395 GTF2E2 VEZF1 NBN IL18RAP HSALNG0017419 ENSG00000234389 IL1R2 MIR4772 SLC9A4
GH02J102424 Enhancer 0.9 FANTOM5 ENCODE 0.4 -6.8 -6842 1.8 BCL11A IRF4 SPI1 BATF POLR2A MAX IKZF1 CEBPG BACH1 JUNB ENSG00000234389 IL1R2 IL18RAP SLC9A4 IL18R1 IL1R1 HSALNG0017419 MIR4772
GH02J102425 Promoter 0.6 EPDnew 0.4 -9.1 -9148 0.1 GTF2E2 SPI1 ZNF589 LEF1 ZBTB11 IL18RAP HSALNG0017419 MIR4772 SLC9A4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4772 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4772 Gene

Latest Assembly
chr2:102,432,289-102,432,366
(GRCh38/hg38)
Size:
78 bases
Orientation:
Plus strand

Previous Assembly
chr2:103,048,749-103,048,826
(GRCh37/hg19 by Entrez Gene)
Size:
78 bases
Orientation:
Plus strand

chr2:103,048,749-103,048,826
(GRCh37/hg19 by Ensembl)
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR4772 Gene

Genes around MIR4772 on UCSC Golden Path with GeneCards custom track
MIR4772 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4772 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4772 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4772 Gene

Proteins for MIR4772 Gene

Post-translational modifications for MIR4772 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4772 Gene

Domains & Families for MIR4772 Gene

Gene Families for MIR4772 Gene

HGNC:
genes like me logo Genes that share domains with MIR4772: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4772 Gene

Function for MIR4772 Gene

Phenotypes From GWAS Catalog for MIR4772 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4772 Gene

Localization for MIR4772 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR4772 gene
Compartment Confidence
extracellular 1
nucleus 1
endosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4772 Gene

Pathways & Interactions for MIR4772 Gene

PathCards logo

SuperPathways for MIR4772 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4772 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4772 Gene

Drugs & Compounds for MIR4772 Gene

No Compound Related Data Available

Transcripts for MIR4772 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4772 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00005901AD_9606 miRNA 22 5

RefSeq: NR_039930,

LncBase: hsa-miR-4772-3p,

miRBase: MIMAT0019927,

TarBase: hsa-miR-4772-3p,

ENA: FR773081.1:1..22:ncRNA, LM382583.1:1..22:ncRNA, LM611414.1:48..69:ncRNA,

URS000075D5D4_9606 precursor_RNA 78 4

RefSeq: NR_039930,

Ensembl: ENST00000581495 (view in UCSC) ,

miRBase: MI0017414,

ENA: LM611414.1:1..78:precursor_RNA,

URS0000411752_9606 miRNA 22 4

RefSeq: NR_039930,

miRBase: MIMAT0019926,

TarBase: hsa-miR-4772-5p,

ENA: FR773082.1:1..22:ncRNA, LM611414.1:12..33:ncRNA,

MIR4772 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR4772 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4772 Gene

No ASD Table

Relevant External Links for MIR4772 Gene

GeneLoc Exon Structure for
MIR4772

Expression for MIR4772 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4772 Gene

genes like me logo Genes that share expression patterns with MIR4772: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4772 Gene

Orthologs for MIR4772 Gene

Evolution for MIR4772 Gene

ENSEMBL:
Gene Tree for MIR4772 (if available)
TreeFam:
Gene Tree for MIR4772 (if available)

No data available for Orthologs for MIR4772 Gene

Paralogs for MIR4772 Gene

No data available for Paralogs for MIR4772 Gene

Variants for MIR4772 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4772 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for MIR4772 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4772

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4772 Gene

Disorders for MIR4772 Gene

Additional Disease Information for MIR4772

No disorders were found for MIR4772 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4772 Gene

Publications for MIR4772 Gene

  1. Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer. (PMID: 27788488) Liu C … Li D (Oncotarget 2016) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4772 Gene

Sources for MIR4772 Gene