microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4765 Gene

Subcategory (RNA class) for MIR4765 Gene

miRNA

Number of RNA Genes sources:

2 / 14

Aliases for MIR4765 Gene

  • MicroRNA 4765 2 3 5
  • Hsa-Mir-4765 3
  • MIMAT0019916 51
  • MI0017406 51
  • MIR4765 2

External Ids for MIR4765 Gene

Previous GeneCards Identifiers for MIR4765 Gene

  • GC02U902453
  • GC02P032862

Summaries for MIR4765 Gene

Entrez Gene Summary for MIR4765 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4765 Gene

MIR4765 (MicroRNA 4765) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4765 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4765 Gene

Genomics for MIR4765 Gene

GeneHancer (GH) Regulatory Elements for MIR4765 Gene

Promoters and enhancers for MIR4765 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J032627 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 -6.9 -6854 3.2 FOXK2 ZBTB40 ZNF217 EP300 CTCF TCF12 SIN3A NRF1 MYC POLR2G TTC27 HSALNG0014097 BIRC6 SLC30A6 DPY30 MIR4765
GH02J032632 Enhancer 0.8 Ensembl ENCODE 0.7 -2.8 -2755 1 JUND FOS RFX1 ZBTB17 FOSL1 TBP NRF1 ADNP GTF3C2 DPF2 DPY30 MIR4765 TTC27
GH02J032646 Enhancer 0.8 Ensembl ENCODE 0.4 +12.0 11979 1.4 JUND FOS ZNF316 CEBPG FOSL1 EZH2 MAFK ATF4 DPF2 MEIS2 TTC27 MIR558 BIRC6 MIR4765 lnc-BIRC6-3
GH02J032648 Enhancer 0.2 Ensembl 0.4 +13.7 13746 0.4 TTC27 MIR4765 lnc-BIRC6-3
GH02J032653 Enhancer 0.2 Ensembl 0.4 +18.1 18146 0.4 TTC27 MIR4765 lnc-BIRC6-3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4765 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4765 Gene

Genomic Locations for MIR4765 Gene
chr2:32,635,255-32,635,331
(GRCh38/hg38)
Size:
77 bases
Orientation:
Plus strand
chr2:32,860,322-32,860,398
(GRCh37/hg19)
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR4765 Gene

Genes around MIR4765 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4765 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4765 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4765 Gene

Proteins for MIR4765 Gene

Post-translational modifications for MIR4765 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4765 Gene

Domains & Families for MIR4765 Gene

Gene Families for MIR4765 Gene

HGNC:
genes like me logo Genes that share domains with MIR4765: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4765 Gene

Function for MIR4765 Gene

Phenotypes From GWAS Catalog for MIR4765 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4765 Gene

Localization for MIR4765 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4765 Gene

Pathways & Interactions for MIR4765 Gene

PathCards logo

SuperPathways for MIR4765 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR4765 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4765 Gene

Drugs & Compounds for MIR4765 Gene

No Compound Related Data Available

Transcripts for MIR4765 Gene

mRNA/cDNA for MIR4765 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
1 ENA transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4765 Gene

No ASD Table

Relevant External Links for MIR4765 Gene

GeneLoc Exon Structure for
MIR4765

Expression for MIR4765 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4765 Gene

genes like me logo Genes that share expression patterns with MIR4765: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4765 Gene

Orthologs for MIR4765 Gene

Evolution for MIR4765 Gene

ENSEMBL:
Gene Tree for MIR4765 (if available)
TreeFam:
Gene Tree for MIR4765 (if available)

No data available for Orthologs for MIR4765 Gene

Paralogs for MIR4765 Gene

No data available for Paralogs for MIR4765 Gene

Variants for MIR4765 Gene

Additional dbSNP identifiers (rs#s) for MIR4765 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4765 Gene

Variant ID Type Subtype PubMed ID
dgv1109e212 CNV gain 25503493
dgv3749n100 CNV gain 25217958
dgv3750n100 CNV gain 25217958
dgv3751n100 CNV gain 25217958
dgv443n27 CNV gain 19166990
dgv6750n54 CNV gain 21841781
esv2422335 CNV duplication 17116639
esv2422472 CNV duplication 17116639
esv2751888 CNV gain 17911159
esv2763243 CNV gain 21179565
esv3590249 CNV gain 21293372
esv3590254 CNV gain 21293372
esv3590256 CNV gain 21293372
esv3891703 CNV gain 25118596
nsv1005939 CNV gain 25217958
nsv456108 CNV gain 19166990
nsv470448 CNV gain 18288195
nsv516173 CNV gain+loss 19592680
nsv581274 CNV gain 21841781
nsv581281 CNV gain 21841781
nsv581283 CNV loss 21841781
nsv833703 CNV loss 17160897

Additional Variant Information for MIR4765 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4765

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4765 Gene

Disorders for MIR4765 Gene

Additional Disease Information for MIR4765

No disorders were found for MIR4765 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4765 Gene

Publications for MIR4765 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR4765 Gene

Sources for MIR4765 Gene