microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4764 Gene

Subcategory (RNA class) for MIR4764 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR4764 Gene

  • MicroRNA 4764 2 3 5
  • Hsa-Mir-4764 2 3
  • MIR4764 2 5
  • MIMAT0019914 50
  • MIMAT0019915 50
  • MI0017405 50

External Ids for MIR4764 Gene

Previous GeneCards Identifiers for MIR4764 Gene

  • GC22U900806
  • GC22M033836

Summaries for MIR4764 Gene

Entrez Gene Summary for MIR4764 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4764 Gene

MIR4764 (MicroRNA 4764) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4764 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4764 Gene

Genomics for MIR4764 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4764 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J033437 Enhancer 0.7 Ensembl ENCODE 600.7 -1.2 -1150 2.4 BACH1 SP1 NFE2 FOS MAFG FOSL2 MAFK EBF1 NFE2L2 NR3C1 MIR4764 piR-52079-131 SYN3 LARGE1
GH22J033440 Enhancer 0.2 Ensembl 0.7 -4.2 -4232 0.2 MIR4764 piR-52079-131 SYN3 LARGE1
GH22J033426 Enhancer 0.2 Ensembl 0.4 +9.5 9468 0.8 MIR4764 lnc-SYN3-6 SYN3 LARGE1
GH22J033444 Enhancer 0.2 Ensembl 0.4 -7.2 -7232 0.2 piR-52079-131 MIR4764 SYN3 LARGE1
GH22J033443 Enhancer 0.2 Ensembl 0.4 -6.8 -6832 0.2 piR-52079-131 MIR4764 SYN3 LARGE1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4764 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4764 Gene

Genomic Locations for MIR4764 Gene
chr22:33,436,582-33,436,669
(GRCh38/hg38)
Size:
88 bases
Orientation:
Minus strand
chr22:33,832,568-33,832,655
(GRCh37/hg19)
Size:
88 bases
Orientation:
Minus strand

Genomic View for MIR4764 Gene

Genes around MIR4764 on UCSC Golden Path with GeneCards custom track
MIR4764 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4764 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4764 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4764 Gene

Proteins for MIR4764 Gene

Post-translational modifications for MIR4764 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4764 Gene

Domains & Families for MIR4764 Gene

Gene Families for MIR4764 Gene

HGNC:
genes like me logo Genes that share domains with MIR4764: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4764 Gene

Function for MIR4764 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4764 Gene

Localization for MIR4764 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4764 Gene

Pathways & Interactions for MIR4764 Gene

PathCards logo

SuperPathways for MIR4764 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4764 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4764 Gene

Drugs & Compounds for MIR4764 Gene

No Compound Related Data Available

Transcripts for MIR4764 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4764 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D5BD_9606 precursor_RNA 88 4

HGNC: 41714,

RefSeq: NR_039921,

Ensembl: ENST00000580680 (view in UCSC) ,

miRBase: MI0017405,

URS0000103638_9606 miRNA 21 3

RefSeq: NR_039921,

miRBase: MIMAT0019914,

ENA: FR773069.1:1..21:ncRNA,

URS000075CBE1_9606 miRNA 22 2

RefSeq: NR_039921,

miRBase: MIMAT0019915,

MIR4764 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4764 Gene

No ASD Table

Relevant External Links for MIR4764 Gene

GeneLoc Exon Structure for
MIR4764

No data available for mRNA/cDNA for MIR4764 Gene

Expression for MIR4764 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4764 Gene

genes like me logo Genes that share expression patterns with MIR4764: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4764 Gene

Orthologs for MIR4764 Gene

Evolution for MIR4764 Gene

ENSEMBL:
Gene Tree for MIR4764 (if available)
TreeFam:
Gene Tree for MIR4764 (if available)

No data available for Orthologs for MIR4764 Gene

Paralogs for MIR4764 Gene

No data available for Paralogs for MIR4764 Gene

Variants for MIR4764 Gene

Additional dbSNP identifiers (rs#s) for MIR4764 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4764 Gene

Variant ID Type Subtype PubMed ID
esv2763261 CNV loss 21179565
nsv1055791 CNV loss 25217958
nsv1064026 CNV loss 25217958

Additional Variant Information for MIR4764 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4764

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4764 Gene

Disorders for MIR4764 Gene

Additional Disease Information for MIR4764

No disorders were found for MIR4764 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4764 Gene

Publications for MIR4764 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4764 Gene

Sources for MIR4764 Gene