microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4763 Gene

Data sources for MIR4763 Gene:

RNA type for MIR4763 Gene

miRNA

Aliases for MIR4763 Gene

External Ids for MIR4763 Gene

Previous GeneCards Identifiers for MIR4763 Gene

  • GC22U900797
  • GC22P046510
  • GC22P046514
  • GC22P046518
  • GC22P046057

Summaries for MIR4763 Gene

Entrez Gene Summary for MIR4763 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4763 Gene

MIR4763 (MicroRNA 4763) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Metastatic brain tumor.

Additional gene information for MIR4763 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4763 Gene

Genomics for MIR4763 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4763 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J046111 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 +0.9 895 5.5 ZNF600 ZNF654 ZNF223 ZIC2 ZBTB10 YY1 CTCF REST ZNF592 TARDBP MIR4763 MIRLET7A3 MIRLET7B HSALNG0136000 HSALNG0136001 PPARA MIRLET7BHG ENSG00000273145 WNT7B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4763 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4763 Gene

Latest Assembly
chr22:46,113,566-46,113,657
(GRCh38/hg38)
Size:
92 bases
Orientation:
Plus strand

Previous Assembly
chr22:46,509,446-46,509,537
(GRCh37/hg19 by Entrez Gene)
Size:
92 bases
Orientation:
Plus strand

Genomic View for MIR4763 Gene

Genes around MIR4763 on UCSC Golden Path with GeneCards custom track
MIR4763 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4763 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4763 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4763 Gene

Proteins for MIR4763 Gene

Post-translational modifications for MIR4763 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4763 Gene

Domains & Families for MIR4763 Gene

Gene Families for MIR4763 Gene

HGNC:
genes like me logo Genes that share domains with MIR4763: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4763 Gene

Function for MIR4763 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4763 Gene

Localization for MIR4763 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4763 Gene

Pathways & Interactions for MIR4763 Gene

PathCards logo

SuperPathways for MIR4763 Gene

SuperPathway Contained pathways
1 Metastatic brain tumor
genes like me logo Genes that share pathways with MIR4763: view

Pathways by source for MIR4763 Gene

1 BioSystems pathway for MIR4763 Gene

Gene Ontology (GO) - Biological Process for MIR4763 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR4763 Gene

Drugs & Compounds for MIR4763 Gene

No Compound Related Data Available

Transcripts for MIR4763 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4763 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075D58D_9606 precursor_RNA 92 3

RefSeq: NR_039920,

Ensembl: ENST00000581461 (view in UCSC) ,

miRBase: MI0017404,

URS00004A40D8_9606 miRNA 24 3

RefSeq: NR_039920,

miRBase: MIMAT0019913,

ENA: FR773068.1:1..24:ncRNA,

URS000075B1DD_9606 miRNA 21 2

RefSeq: NR_039920,

miRBase: MIMAT0019912,

MIR4763 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4763 Gene

No ASD Table

Relevant External Links for MIR4763 Gene

GeneLoc Exon Structure for
MIR4763

No data available for mRNA/cDNA for MIR4763 Gene

Expression for MIR4763 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4763 Gene

mRNA differential expression in normal tissues according to GTEx for MIR4763 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x5.3).
genes like me logo Genes that share expression patterns with MIR4763: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4763 Gene

Orthologs for MIR4763 Gene

Evolution for MIR4763 Gene

ENSEMBL:
Gene Tree for MIR4763 (if available)
TreeFam:
Gene Tree for MIR4763 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR4763

No data available for Orthologs for MIR4763 Gene

Paralogs for MIR4763 Gene

No data available for Paralogs for MIR4763 Gene

Variants for MIR4763 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4763 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4763 Gene

Variant ID Type Subtype PubMed ID
dgv2469n106 OTHER inversion 24896259
nsv1152661 OTHER inversion 26484159
nsv459905 CNV loss 19166990
nsv471212 CNV loss 18288195
nsv471213 CNV gain 18288195
nsv516279 CNV loss 19592680
nsv829281 CNV gain 20364138
nsv829285 CNV gain 20364138
nsv834224 CNV loss 17160897

Additional Variant Information for MIR4763 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4763
Leiden Open Variation Database (LOVD)
MIR4763

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4763 Gene

Disorders for MIR4763 Gene

Additional Disease Information for MIR4763

No disorders were found for MIR4763 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4763 Gene

Publications for MIR4763 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4763 Gene

Sources for MIR4763 Gene