microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4752 Gene

Data sources for MIR4752 Gene:

RNA type for MIR4752 Gene

miRNA

Aliases for MIR4752 Gene

External Ids for MIR4752 Gene

Previous GeneCards Identifiers for MIR4752 Gene

  • GC19U901544
  • GC19P054848
  • GC19P054859
  • GC19P054877
  • GC19P054358
  • GC19P054363
  • GC19P054477
  • GC19P054516
  • GC19P054526
  • GC19P054571
  • GC19P054374
  • GC19P054387
  • GC19P054394
  • GC19P054401
  • GC19P054440
  • GC19P054450
  • GC19P054460
  • GC19P054469
  • GC19P055371
  • GC19P055608

Summaries for MIR4752 Gene

Entrez Gene Summary for MIR4752 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4752 Gene

MIR4752 (MicroRNA 4752) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4752 Gene

Genomics for MIR4752 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4752 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J054279 Promoter/Enhancer 1.1 EPDnew Ensembl ENCODE dbSUPER 250.7 -1.4 -1408 1.8 SPI1 LILRB2 MIR4752 lnc-LILRB5-4 LILRB5 ENSG00000275210
GH19J054282 Enhancer 0.7 FANTOM5 ENCODE dbSUPER 250.7 +0.8 840 1.1 KLF1 IKZF1 LILRB2 MIR4752 LILRB3 LAIR1 LILRA6 LILRB5 ENSG00000249189 OSCAR MYADM VSTM1
GH19J054285 Promoter/Enhancer 0.5 Ensembl dbSUPER 0.7 +3.6 3592 0.2 LILRB5 ENSG00000249189 LILRA6 LILRB3 TTYH1 LILRB2 MIR4752 ENSG00000240197 LILRA5 ENSG00000275210
GH19J054289 Promoter/Enhancer 0.5 Ensembl dbSUPER 0.4 +7.6 7592 0.2 LILRB5 ENSG00000249189 LILRA6 LILRB3 ENSG00000240197 LILRB2 MIR4752 LILRA5 ENSG00000275210
GH19J054287 Promoter 0.3 Ensembl 0.4 +5.7 5692 0.4 LILRB5 ENSG00000249189 LILRA6 LILRB3 TTYH1 ENSG00000240197 LILRB2 MIR4752 LILRA5 ENSG00000275210
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4752 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4752 Gene

Latest Assembly
chr19:54,282,109-54,282,180
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand

Previous Assembly
chr19:54,785,964-54,786,035
(GRCh37/hg19 by Entrez Gene)
Size:
72 bases
Orientation:
Plus strand

chr19:54,785,964-54,786,035
(GRCh37/hg19 by Ensembl)
Size:
72 bases
Orientation:
Plus strand

Alternative Locations (GRCh38/hg38)

  • chr19(ALT_REF_LOCI_1):256,848-256,919 (+)
  • chr19(ALT_REF_LOCI_2):256,727-256,798 (+)
  • chr19(ALT_REF_LOCI_8):257,103-257,174 (+)
  • chr19(ALT_REF_LOCI_9):257,078-257,149 (+)

Genomic View for MIR4752 Gene

Genes around MIR4752 on UCSC Golden Path with GeneCards custom track
MIR4752 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR4752 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4752 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4752 Gene

Proteins for MIR4752 Gene

Post-translational modifications for MIR4752 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4752 Gene

Domains & Families for MIR4752 Gene

Gene Families for MIR4752 Gene

HGNC:
genes like me logo Genes that share domains with MIR4752: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4752 Gene

Function for MIR4752 Gene

Phenotypes From GWAS Catalog for MIR4752 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4752 Gene

Localization for MIR4752 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4752 Gene

Pathways & Interactions for MIR4752 Gene

PathCards logo

SuperPathways for MIR4752 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4752 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4752 Gene

Drugs & Compounds for MIR4752 Gene

No Compound Related Data Available

Transcripts for MIR4752 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4752 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075AB7E_9606 precursor_RNA 72 3

RefSeq: NR_039907,

Ensembl: ENST00000579672 (view in UCSC) ,

miRBase: MI0017391,

URS00002217EB_9606 miRNA 22 3

RefSeq: NR_039907,

miRBase: MIMAT0019889,

ENA: FR773049.1:1..22:ncRNA,

MIR4752 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4752 Gene

No ASD Table

Relevant External Links for MIR4752 Gene

GeneLoc Exon Structure for
MIR4752

No data available for mRNA/cDNA for MIR4752 Gene

Expression for MIR4752 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4752 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR4752

genes like me logo Genes that share expression patterns with MIR4752: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4752 Gene

Orthologs for MIR4752 Gene

Evolution for MIR4752 Gene

ENSEMBL:
Gene Tree for MIR4752 (if available)
TreeFam:
Gene Tree for MIR4752 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR4752

No data available for Orthologs for MIR4752 Gene

Paralogs for MIR4752 Gene

No data available for Paralogs for MIR4752 Gene

Variants for MIR4752 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR4752 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR4752 Gene

Variant ID Type Subtype PubMed ID
dgv1074e212 CNV gain 25503493
dgv3654n100 CNV gain 25217958
dgv3657n100 CNV gain 25217958
dgv3660n100 CNV gain 25217958
dgv3661n100 CNV gain+loss 25217958
dgv3662n100 CNV gain 25217958
dgv6549n54 CNV gain 21841781
esv2718812 CNV deletion 23290073
esv2718860 CNV deletion 23290073
esv2718864 CNV deletion 23290073
esv2758771 CNV gain+loss 17122850
esv2763032 CNV gain+loss 21179565
esv3574853 CNV gain 25503493
esv3644792 CNV loss 21293372
esv3644793 CNV gain 21293372
nsv1148744 OTHER inversion 26484159
nsv428371 CNV gain+loss 18775914
nsv442471 CNV gain 18776908
nsv528370 CNV loss 19592680
nsv580193 CNV gain 21841781
nsv833878 CNV loss 17160897
nsv963078 CNV duplication 23825009

Additional Variant Information for MIR4752 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4752
Leiden Open Variation Database (LOVD)
MIR4752

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4752 Gene

Disorders for MIR4752 Gene

Additional Disease Information for MIR4752

No disorders were found for MIR4752 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4752 Gene

Publications for MIR4752 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4752 Gene

Sources for MIR4752 Gene