Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4743 Gene

Subcategory (RNA class) for MIR4743 Gene


Quality Score for this RNA gene is


Aliases for MIR4743 Gene

  • MicroRNA 4743 2 3 5
  • Hsa-Mir-4743 3

External Ids for MIR4743 Gene

Previous GeneCards Identifiers for MIR4743 Gene

  • GC18U900661
  • GC18P046198

Summaries for MIR4743 Gene

Entrez Gene Summary for MIR4743 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4743 Gene

MIR4743 (MicroRNA 4743) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4743 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4743 Gene

Genomics for MIR4743 Gene

GeneHancer (GH) Regulatory Elements for MIR4743 Gene

Promoters and enhancers for MIR4743 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18I048673 Enhancer 1.1 Ensembl ENCODE 0.8 +4.7 4701 4.2 HDGF ARID4B SIN3A ZNF2 ZNF48 YY1 GLIS2 ZNF143 RUNX3 SP3 CTIF DYM MIR4743 LOC105372107
GH18I048679 Enhancer 0.7 Ensembl ENCODE 0.4 +9.9 9945 2.5 CTCF GLIS1 RAD21 NR2F2 CTIF MIR4743 LOC105372107
GH18I048665 Enhancer 0.7 ENCODE 0.4 -6.2 -6165 0.2 CTCF RAD21 GLIS2 SMC3 ZNF143 ZNF391 NR2F6 ZNF600 ZNF654 MAZ ENSG00000279629 MIR4743 CTIF
GH18I048664 Enhancer 0.6 ENCODE 0.4 -6.3 -6304 0 CTCF MAZ RXRA ZFP37 TRIM22 RAD21 GLIS2 ZNF143 HNF4A ZNF391 ENSG00000279629 MIR4743 CTIF
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4743 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4743 Gene

Genomic Locations for MIR4743 Gene
69 bases
Plus strand

Genomic View for MIR4743 Gene

Genes around MIR4743 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4743 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4743 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4743 Gene

Proteins for MIR4743 Gene

Post-translational modifications for MIR4743 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4743 Gene

Domains & Families for MIR4743 Gene

Gene Families for MIR4743 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4743: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4743 Gene

Function for MIR4743 Gene

Phenotypes From GWAS Catalog for MIR4743 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4743 Gene

Localization for MIR4743 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4743 Gene

Pathways & Interactions for MIR4743 Gene

SuperPathways for MIR4743 Gene

No Data Available

Interacting Proteins for MIR4743 Gene

Gene Ontology (GO) - Biological Process for MIR4743 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4743 Gene

Drugs & Compounds for MIR4743 Gene

No Compound Related Data Available

Transcripts for MIR4743 Gene

mRNA/cDNA for MIR4743 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4743 Gene

No ASD Table

Relevant External Links for MIR4743 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4743 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4743 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4743 Gene

Orthologs for MIR4743 Gene

Evolution for MIR4743 Gene

Gene Tree for MIR4743 (if available)
Gene Tree for MIR4743 (if available)

No data available for Orthologs for MIR4743 Gene

Paralogs for MIR4743 Gene

No data available for Paralogs for MIR4743 Gene

Variants for MIR4743 Gene

Sequence variations from dbSNP and Humsavar for MIR4743 Gene

SNP ID Clin Chr 18 pos Variation AA Info Type
rs1000659400 -- 48,669,042(+) C/T upstream_transcript_variant
rs1001010188 -- 48,668,809(+) G/A upstream_transcript_variant
rs1002484826 -- 48,668,707(+) A/G upstream_transcript_variant
rs1004859838 -- 48,671,051(+) T/C/G downstream_transcript_variant
rs1005452365 -- 48,669,903(+) A/G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4743 Gene

Variant ID Type Subtype PubMed ID
nsv833643 CNV gain 17160897
nsv833642 CNV gain 17160897
nsv576857 CNV loss 21841781
nsv509694 CNV insertion 20534489
nsv2291 CNV insertion 18451855

Additional Variant Information for MIR4743 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4743 Gene

Disorders for MIR4743 Gene

Additional Disease Information for MIR4743

No disorders were found for MIR4743 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4743 Gene

Publications for MIR4743 Gene

  1. Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients. (PMID: 25201637) Fan HM … Lu J (Journal of psychiatric research 2014) 3 58
  2. Transcription factors are targeted by differentially expressed miRNAs in primates. (PMID: 22454130) Dannemann M … Kelso J (Genome biology and evolution 2012) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4743 Gene

Sources for MIR4743 Gene

Loading form....