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Aliases for MIR4740 Gene

Subcategory (RNA class) for MIR4740 Gene


Quality Score for this RNA gene is


Aliases for MIR4740 Gene

  • MicroRNA 4740 2 3 5
  • Hsa-Mir-4740 3

External Ids for MIR4740 Gene

Previous GeneCards Identifiers for MIR4740 Gene

  • GC17U901640
  • GC02M109931
  • GC17M079377

Summaries for MIR4740 Gene

Entrez Gene Summary for MIR4740 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4740 Gene

MIR4740 (MicroRNA 4740) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4740 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4740 Gene

Genomics for MIR4740 Gene

GeneHancer (GH) Regulatory Elements for MIR4740 Gene

Promoters and enhancers for MIR4740 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I081384 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.8 +4.7 4674 22.4 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF263 BAHCC1 ENSG00000279692 ENSG00000262877 CEP131 GPS1 HGS ENSG00000260011 FAAP100 ENSG00000260369 ENSG00000265678
GH17I081416 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -19.8 -19757 7.6 SIN3A FEZF1 GLIS2 KLF7 FOS DEK SP3 SMARCB1 GMEB1 GLIS1 HGS MAFG FSCN2 CCDC137 NPLOC4 MIR4740 BAHCC1 GC17M081444
GH17I081412 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 -12.1 -12129 1 HDAC1 ATF1 TAF9B KLF17 ZBTB40 TCF12 ZNF766 EGR1 ETV6 ATF7 MIR4740 BAHCC1 GC17M081444
GH17I081409 Enhancer 1 ENCODE dbSUPER 0.4 -8.5 -8548 0.1 HDAC1 PKNOX1 ARNT SIN3A EGR1 ZNF143 CREM ZBTB2 REST ZNF592 MIR4740 BAHCC1 GC17M081444
GH17I081424 Enhancer 1.1 ENCODE dbSUPER 0.3 -24.0 -23998 0.2 HDGF YBX1 PLRG1 ZBTB7B ZNF155 ZNF114 YY2 ZIK1 ZNF662 ZNF398 OGFOD3 FAAP100 CEP131 ENSG00000262877 TEPSIN ENSG00000265678 HEXDC HGS ENSG00000260563 ENSG00000260369
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4740 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4740 Gene

Genomic Locations for MIR4740 Gene
63 bases
Minus strand

Genomic View for MIR4740 Gene

Genes around MIR4740 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4740 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4740 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4740 Gene

ORGUL Member Location for MIR4740 Gene

ORGUL Member Location for MIR4740 gene

Proteins for MIR4740 Gene

Post-translational modifications for MIR4740 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4740 Gene

Domains & Families for MIR4740 Gene

Gene Families for MIR4740 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4740: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4740 Gene

Function for MIR4740 Gene

Phenotypes From GWAS Catalog for MIR4740 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4740 Gene

Localization for MIR4740 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4740 Gene

Pathways & Interactions for MIR4740 Gene

SuperPathways for MIR4740 Gene

No Data Available

Interacting Proteins for MIR4740 Gene

Gene Ontology (GO) - Biological Process for MIR4740 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4740 Gene

Drugs & Compounds for MIR4740 Gene

No Compound Related Data Available

Transcripts for MIR4740 Gene

mRNA/cDNA for MIR4740 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4740 Gene

No ASD Table

Relevant External Links for MIR4740 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4740 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4740 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4740 Gene:

genes like me logo Genes that share expression patterns with MIR4740: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4740 Gene

Orthologs for MIR4740 Gene

Evolution for MIR4740 Gene

Gene Tree for MIR4740 (if available)
Gene Tree for MIR4740 (if available)

No data available for Orthologs for MIR4740 Gene

Paralogs for MIR4740 Gene

No data available for Paralogs for MIR4740 Gene

Variants for MIR4740 Gene

Sequence variations from dbSNP and Humsavar for MIR4740 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000218577 -- 81,402,468(-) T/C upstream_transcript_variant
rs1000569156 -- 81,402,306(-) C/T upstream_transcript_variant
rs1001725724 -- 81,402,767(-) C/T upstream_transcript_variant
rs1002007296 -- 81,401,577(-) C/T upstream_transcript_variant
rs1002073239 -- 81,402,527(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4740 Gene

Variant ID Type Subtype PubMed ID
nsv952389 CNV deletion 24416366
nsv828134 CNV loss 20364138
nsv828128 CNV loss 20364138
nsv576175 CNV loss 21841781
nsv576174 CNV loss 21841781
nsv576173 CNV loss 21841781
nsv428351 CNV gain 18775914
esv26223 CNV gain+loss 19812545

Additional Variant Information for MIR4740 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4740 Gene

Disorders for MIR4740 Gene

Additional Disease Information for MIR4740

No disorders were found for MIR4740 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4740 Gene

Publications for MIR4740 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4740 Gene

Sources for MIR4740 Gene

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