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Aliases for MIR4739 Gene

Subcategory (RNA class) for MIR4739 Gene


Quality Score for this RNA gene is


Aliases for MIR4739 Gene

  • MicroRNA 4739 2 3 5
  • Hsa-Mir-4739 3
  • Mir-4739 3

External Ids for MIR4739 Gene

Previous GeneCards Identifiers for MIR4739 Gene

  • GC17U901652
  • GC17M077683

Summaries for MIR4739 Gene

Entrez Gene Summary for MIR4739 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4739 Gene

MIR4739 (MicroRNA 4739) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4739 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4739 Gene

Genomics for MIR4739 Gene

GeneHancer (GH) Regulatory Elements for MIR4739 Gene

Promoters and enhancers for MIR4739 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I079706 Enhancer 0.7 Ensembl 550.8 -0.7 -733 2.2 CTCF KLF1 LEF1 RB1 ZBTB21 KLF17 SIN3A ZIC2 RAD21 ZNF335 LINC02078 MIR4739 PIR42685
GH17I079702 Enhancer 0.5 ENCODE 0.4 +5.0 5049 0.1 CTCF KLF1 GLIS1 ZNF600 ZEB2 MIR4739 LOC101929831
GH17I079665 Enhancer 0.6 ENCODE 0.3 +41.9 41854 0.7 SMARCE1 ZNF687 DPF2 REST SP1 ZNF217 GATA3 CTBP1 PRDM4 CBX2 LOC101929831 MIR4739
GH17I079690 Enhancer 0.3 FANTOM5 0.4 +17.2 17218 0 MIR4739 LOC101929831
GH17I079691 Enhancer 0.2 ENCODE 0.4 +15.2 15243 0.1 MIR4739 LOC101929831
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4739 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4739 Gene

Genomic Locations for MIR4739 Gene
74 bases
Minus strand

Genomic View for MIR4739 Gene

Genes around MIR4739 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4739 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4739 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4739 Gene

ORGUL Member Location for MIR4739 Gene

ORGUL Member Location for MIR4739 gene

Proteins for MIR4739 Gene

Post-translational modifications for MIR4739 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4739 Gene

Domains & Families for MIR4739 Gene

Gene Families for MIR4739 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4739: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4739 Gene

Function for MIR4739 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4739 Gene

Localization for MIR4739 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4739 Gene

Pathways & Interactions for MIR4739 Gene

SuperPathways for MIR4739 Gene

No Data Available

Interacting Proteins for MIR4739 Gene

Gene Ontology (GO) - Biological Process for MIR4739 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4739 Gene

Drugs & Compounds for MIR4739 Gene

No Compound Related Data Available

Transcripts for MIR4739 Gene

mRNA/cDNA for MIR4739 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4739 Gene

No ASD Table

Relevant External Links for MIR4739 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4739 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4739 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4739 Gene

Orthologs for MIR4739 Gene

Evolution for MIR4739 Gene

Gene Tree for MIR4739 (if available)
Gene Tree for MIR4739 (if available)

No data available for Orthologs for MIR4739 Gene

Paralogs for MIR4739 Gene

No data available for Paralogs for MIR4739 Gene

Variants for MIR4739 Gene

Sequence variations from dbSNP and Humsavar for MIR4739 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs111311094 -- 79,708,331(-) G/C upstream_transcript_variant
rs111599301 -- 79,709,204(-) C/A upstream_transcript_variant
rs111756458 -- 79,709,186(-) T/C upstream_transcript_variant
rs111789255 -- 79,709,218(-) G/C upstream_transcript_variant
rs112037869 -- 79,709,193(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4739 Gene

Variant ID Type Subtype PubMed ID
nsv9594 CNV gain 18304495
nsv952381 CNV deletion 24416366
esv28226 CNV gain+loss 19812545
dgv590e214 CNV loss 21293372

Additional Variant Information for MIR4739 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4739 Gene

Disorders for MIR4739 Gene

Additional Disease Information for MIR4739

No disorders were found for MIR4739 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4739 Gene

Publications for MIR4739 Gene

  1. MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP3. (PMID: 28340487) Elsafadi M … Mahmood A (Stem cell research 2017) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4739 Gene

Sources for MIR4739 Gene

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