microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR4737 Gene

Subcategory (RNA class) for MIR4737 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR4737 Gene

  • MicroRNA 4737 2 3 5
  • Hsa-Mir-4737 2 3
  • MIR4737 2 5
  • MIMAT0019863 50
  • MI0017374 50

External Ids for MIR4737 Gene

Previous GeneCards Identifiers for MIR4737 Gene

  • GC17U901647
  • GC17M058123
  • GC17M058127
  • GC17M058131

Summaries for MIR4737 Gene

Entrez Gene Summary for MIR4737 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4737 Gene

MIR4737 (MicroRNA 4737) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4737 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR4737 Gene

Genomics for MIR4737 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR4737 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J060037 Enhancer 0.9 ENCODE 0.4 +5.8 5840 0.2 GATAD2A CTCF TEAD4 ZNF629 TFE3 KDM1A JUND ZNF143 RXRB RAD21 RPS6KB1 TUBD1 MIR4737 HSALNG0117814 HEATR6 RNFT1
GH17J060025 Promoter 0.6 Ensembl 0.4 +16.2 16205 3 SMARCA5 DDX20 SMARCE1 ENSG00000274378 HSALNG0117814 MIR4737 HEATR6 RNFT1
GH17J060034 Enhancer 0.4 Ensembl 0.4 +8.4 8402 1 RAD21 CTCF ZNF654 RPS6KB1 TUBD1 HSALNG0117814 MIR4737 HEATR6 RNFT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR4737 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR4737 Gene

Genomic Locations for MIR4737 Gene
chr17:60,043,025-60,043,105
(GRCh38/hg38)
Size:
81 bases
Orientation:
Minus strand
chr17:58,120,386-58,120,466
(GRCh37/hg19)
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR4737 Gene

Genes around MIR4737 on UCSC Golden Path with GeneCards custom track
MIR4737 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR4737 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4737 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4737 Gene

Proteins for MIR4737 Gene

Post-translational modifications for MIR4737 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4737 Gene

Domains & Families for MIR4737 Gene

Gene Families for MIR4737 Gene

HGNC:
genes like me logo Genes that share domains with MIR4737: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR4737 Gene

Function for MIR4737 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4737 Gene

Localization for MIR4737 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4737 Gene

Pathways & Interactions for MIR4737 Gene

PathCards logo

SuperPathways for MIR4737 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR4737 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR4737 Gene

Drugs & Compounds for MIR4737 Gene

No Compound Related Data Available

Transcripts for MIR4737 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR4737 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075DACB_9606 precursor_RNA 81 4

HGNC: 41669,

RefSeq: NR_039890,

Ensembl: ENST00000583979 (view in UCSC) ,

miRBase: MI0017374,

URS000057DFC6_9606 miRNA 20 3

RefSeq: NR_039890,

miRBase: MIMAT0019863,

ENA: FR773027.1:1..20:ncRNA,

MIR4737 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4737 Gene

No ASD Table

Relevant External Links for MIR4737 Gene

GeneLoc Exon Structure for
MIR4737

No data available for mRNA/cDNA for MIR4737 Gene

Expression for MIR4737 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4737 Gene

genes like me logo Genes that share expression patterns with MIR4737: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4737 Gene

Orthologs for MIR4737 Gene

Evolution for MIR4737 Gene

ENSEMBL:
Gene Tree for MIR4737 (if available)
TreeFam:
Gene Tree for MIR4737 (if available)

No data available for Orthologs for MIR4737 Gene

Paralogs for MIR4737 Gene

No data available for Paralogs for MIR4737 Gene

Variants for MIR4737 Gene

Additional dbSNP identifiers (rs#s) for MIR4737 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4737 Gene

Variant ID Type Subtype PubMed ID
esv2653138 CNV deletion 19546169
esv26907 CNV loss 19812545
esv2758700 CNV gain+loss 17122850
nsv428348 CNV gain 18775914
nsv471702 CNV gain 15918152
nsv499622 OTHER inversion 21111241
nsv7295 OTHER inversion 18451855
nsv833502 CNV gain 17160897

Additional Variant Information for MIR4737 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4737

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR4737 Gene

Disorders for MIR4737 Gene

No disorders were found for MIR4737 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4737 Gene

Publications for MIR4737 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR4737 Gene

Sources for MIR4737 Gene