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MIR4737 Gene(RNA Gene)

MicroRNA 4737

GCID:
GC17M060046
GIFtS:
13
Genes Participants
UDN Logo

Aliases for MIR4737 Gene

Subcategory (RNA class) for MIR4737 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4737 Gene

  • MicroRNA 4737 2 3 5
  • Hsa-Mir-4737 3

External Ids for MIR4737 Gene

ORGUL Members for MIR4737 Gene

Previous GeneCards Identifiers for MIR4737 Gene

  • GC17U901647
  • GC17M058123
  • GC17M058127
  • GC17M058131

Summaries for MIR4737 Gene

Entrez Gene Summary for MIR4737 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4737 Gene

MIR4737 (MicroRNA 4737) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4737 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4737 Gene

Genomics for MIR4737 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR4737 Gene

Promoters and enhancers for MIR4737 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH17I060037 Enhancer 1.1 Ensembl ENCODE 0.4 +5.7 5723 0.8 ARID4B DMAP1 ZNF2 ZNF48 ZNF143 KLF7 RUNX3 DEK MIER2 REST GC17P060035 RPS6KB1 TUBD1 HEATR6 MIR4737 GC17P059994
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4737 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4737 Gene

Genomic Locations for MIR4737 Gene
chr17:60,043,025-60,043,105
(GRCh38/hg38)
Size:
81 bases
Orientation:
Minus strand
chr17:58,120,386-58,120,466
(GRCh37/hg19)

Genomic View for MIR4737 Gene

Genes around MIR4737 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4737 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4737 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4737 Gene

ORGUL Member Location for MIR4737 Gene

ORGUL Member Location for MIR4737 gene

Proteins for MIR4737 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4737 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4737 Gene

Domains & Families for MIR4737 Gene

Gene Families for MIR4737 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4737: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4737 Gene

Function for MIR4737 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4737 Gene

Localization for MIR4737 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4737 Gene

Pathways & Interactions for MIR4737 Gene

SuperPathways for MIR4737 Gene

PathCards logo More details on SuperPathways for MIR4737
No Data Available

Interacting Proteins for MIR4737 Gene

Gene Ontology (GO) - Biological Process for MIR4737 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4737 Gene

Drugs & Compounds for MIR4737 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4737 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR4737 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4737 Gene

No ASD Table

Relevant External Links for MIR4737 Gene

GeneLoc Exon Structure for
MIR4737
ECgene alternative splicing isoforms for
MIR4737

Expression for MIR4737 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4737 Gene

mRNA expression in normal human tissues for MIR4737 Gene
mRNA expression by GTEx for MIR4737 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4737 Gene:

MIR4737
genes like me logo Genes that share expression patterns with MIR4737: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4737 Gene

Orthologs for MIR4737 Gene

Evolution for MIR4737 Gene

ENSEMBL:
Gene Tree for MIR4737 (if available)
TreeFam:
Gene Tree for MIR4737 (if available)

No data available for Orthologs for MIR4737 Gene

Paralogs for MIR4737 Gene

No data available for Paralogs for MIR4737 Gene

Variants for MIR4737 Gene

Sequence variations from dbSNP and Humsavar for MIR4737 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1001605364 -- 60,043,407(-) T/C upstream_transcript_variant
rs1002190369 -- 60,044,736(-) G/A upstream_transcript_variant
rs1002670351 -- 60,044,484(-) T/A upstream_transcript_variant
rs1002901497 -- 60,045,036(-) A/G upstream_transcript_variant
rs1004740315 -- 60,044,791(-) CAGC/CAGCAGC upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4737 Gene

Variant ID Type Subtype PubMed ID
nsv833502 CNV gain 17160897
nsv7295 OTHER inversion 18451855
nsv499622 OTHER inversion 21111241
nsv471702 CNV gain 15918152
nsv428348 CNV gain 18775914
esv2758700 CNV gain+loss 17122850
esv26907 CNV loss 19812545
esv2653138 CNV deletion 19546169

Additional Variant Information for MIR4737 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4737

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4737 Gene

Disorders for MIR4737 Gene

Additional Disease Information for MIR4737

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR4737 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4737 Gene

Publications for MIR4737 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4737 Gene

Sources for MIR4737 Gene

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